dc.date.accessioned | 2015-03-17T11:57:02Z | |
dc.date.available | 2015-03-17T11:57:02Z | |
dc.date.created | 2015-03-15T20:03:48Z | |
dc.date.issued | 2015 | |
dc.identifier.citation | Mellingsæter, Marte Wyller, Torgeir Bruun Ranhoff, Anette Hylen Bogdanovic, Nenad Wyller, Vegard Bruun . Reduced Sympathetic Response to Head-Up Tilt in Subjects with Mild Cognitive Impairment or Mild Alzheimer's Dementia. Dementia and geriatric cognitive disorders extra. 2015, 5(1), 107-115 | |
dc.identifier.uri | http://hdl.handle.net/10852/43245 | |
dc.description.abstract | Background: Hemodynamic control was compared in patients with mild cognitive impairment (MCI) or mild Alzheimer's dementia (AD) as well as in healthy elderly subjects. Methods: Noninvasive, continuous hemodynamic recordings were obtained from 14 patients and 48 controls during supine rest (tilt of 30 and 70°). Cardiac output, end-diastolic volume, total peripheral resistance, heart rate variability (HRV), systolic blood pressure variability (SBPV), and baroreceptor sensitivity were calculated. Results: At 70° tilt, the HRV indices differed significantly, with higher high-frequency (HF) variability as well as lower low-frequency (LF) variability and LF/HF ratios in the patients. The patients had significantly lower SBPV in the LF range at 30° tilt. Conclusions: The results indicate a poorer sympathetic response to orthostatic stress in MCI and mild AD. | en_US |
dc.language | EN | |
dc.language.iso | en | en_US |
dc.rights | Attribution-NonCommercial 3.0 Unported | |
dc.rights.uri | https://creativecommons.org/licenses/by-nc/3.0/ | |
dc.title | Reduced Sympathetic Response to Head-Up Tilt in Subjects with Mild Cognitive Impairment or Mild Alzheimer's Dementia | en_US |
dc.type | Journal article | en_US |
dc.creator.author | Mellingsæter, Marte | |
dc.creator.author | Wyller, Torgeir Bruun | |
dc.creator.author | Ranhoff, Anette Hylen | |
dc.creator.author | Bogdanovic, Nenad | |
dc.creator.author | Wyller, Vegard Bruun | |
cristin.unitcode | 185,53,0,0 | |
cristin.unitname | Institutt for klinisk medisin | |
cristin.ispublished | true | |
cristin.fulltext | original | |
cristin.qualitycode | 1 | |
dc.identifier.cristin | 1232038 | |
dc.identifier.bibliographiccitation | info:ofi/fmt:kev:mtx:ctx&ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Dementia and geriatric cognitive disorders extra&rft.volume=5&rft.spage=107&rft.date=2015 | |
dc.identifier.jtitle | Dementia and geriatric cognitive disorders extra | |
dc.identifier.volume | 5 | |
dc.identifier.issue | 1 | |
dc.identifier.startpage | 107 | |
dc.identifier.endpage | 115 | |
dc.identifier.doi | http://dx.doi.org/10.1159/000375297 | |
dc.identifier.urn | URN:NBN:no-47632 | |
dc.type.document | Tidsskriftartikkel | en_US |
dc.type.peerreviewed | Peer reviewed | |
dc.source.issn | 1664-5464 | |
dc.identifier.fulltext | Fulltext https://www.duo.uio.no/bitstream/handle/10852/43245/4/375297.pdf | |
dc.type.version | PublishedVersion | |