dc.contributor.author | Stølen, Ole Andreas | |
dc.date.accessioned | 2014-09-17T22:00:20Z | |
dc.date.available | 2014-09-17T22:00:20Z | |
dc.date.issued | 2014 | |
dc.identifier.citation | Stølen, Ole Andreas. Tidlig introduksjon av kumelk i spedbarnsalder og risiko for type 1 diabetes. Master thesis, University of Oslo, 2014 | |
dc.identifier.uri | http://hdl.handle.net/10852/41092 | |
dc.description.abstract | Background: Several different factors point to the significance of the role of non-genetic causes in the etiology of type 1 diabetes. Some studies have suggested a positive correlation between early exposure to cow s milk in infancy and increased later risk of developing the disease, while other studies have not found such a correlation. The issue is still unresolved, and in this systematic review I will investigate the most relevant literature on the subject. Methods: I conducted a systematic literature search in Medline and Embase databases, using predetermined inclusion and exclusion criteria. All studies comparing infant cow s milk exposure with type 1 diabetes risk were included in the review. A total of 19 studies were included, most of them being retrospective case-control designed studies. Results: The included studies were categorized in terms of whether they showed a positive, negative or no correlation between infant cow s milk exposure and risk of type 1 diabetes, and with regard to the quality of the studies. Six of the studies results were considered to be positive and convincing for increased risk of type 1 diabetes with early infant exposure, four were positive and plausible or positive and lacking , and 12 showed no effect . Conclusions: Divergent results could be seen between the different studies included in this review with regards to whether early infant cow s milk exposure increases the risk of developing type 1 diabetes or not. On the basis of the findings in this review, one can therefore not conclude with a positive, negative or a non-existing relationship between the respective exposure and the disease. | nor |
dc.description.abstract | Background: Several different factors point to the significance of the role of non-genetic causes in the etiology of type 1 diabetes. Some studies have suggested a positive correlation between early exposure to cow s milk in infancy and increased later risk of developing the disease, while other studies have not found such a correlation. The issue is still unresolved, and in this systematic review I will investigate the most relevant literature on the subject. Methods: I conducted a systematic literature search in Medline and Embase databases, using predetermined inclusion and exclusion criteria. All studies comparing infant cow s milk exposure with type 1 diabetes risk were included in the review. A total of 19 studies were included, most of them being retrospective case-control designed studies. Results: The included studies were categorized in terms of whether they showed a positive, negative or no correlation between infant cow s milk exposure and risk of type 1 diabetes, and with regard to the quality of the studies. Six of the studies results were considered to be positive and convincing for increased risk of type 1 diabetes with early infant exposure, four were positive and plausible or positive and lacking , and 12 showed no effect . Conclusions: Divergent results could be seen between the different studies included in this review with regards to whether early infant cow s milk exposure increases the risk of developing type 1 diabetes or not. On the basis of the findings in this review, one can therefore not conclude with a positive, negative or a non-existing relationship between the respective exposure and the disease. | eng |
dc.language.iso | nor | |
dc.subject | type | |
dc.subject | 1 | |
dc.subject | diabetes | |
dc.subject | autoimmun | |
dc.subject | diabetes | |
dc.subject | kumelk | |
dc.subject | spedbarn | |
dc.subject | etiologi | |
dc.title | Tidlig introduksjon av kumelk i spedbarnsalder og risiko for type 1 diabetes | nor |
dc.title | Early introduction of cow's milk in infancy and risk of type 1 diabetes | eng |
dc.type | Master thesis | |
dc.date.updated | 2014-09-18T22:02:07Z | |
dc.creator.author | Stølen, Ole Andreas | |
dc.identifier.urn | URN:NBN:no-45675 | |
dc.type.document | Prosjektoppgave | |
dc.identifier.fulltext | Fulltext https://www.duo.uio.no/bitstream/handle/10852/41092/1/Prosjektoppgave---Ole-Andreas-Stlen.pdf | |