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Now showing items 1-100 of 10783
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Background
Cryptogenic stroke is a heterogeneous condition, with a wide spectrum of possible underlying causes for which the optimal secondary prevention may differ substantially. Attempting a correct ...
(Doctoral thesis / Doktoravhandling, 2012)
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
Background
From the public health perspective, epidemiological data of child mental health and psychosocial correlates were necessary and very lacking in Lithuanian society that has been undergoing rapid ...
(Doctoral thesis / Doktoravhandling, 2017)
In order to optimize the treatment and outcome for cancer patients, biomarkers for early detection, prediction of treatment and estimation of prognosis are needed.
The aim of this thesis was to investigate if microRNAs ...
(Doctoral thesis / Doktoravhandling, 2012)
Introduction<br>
This three group randomized controlled trial evaluated the effect of a Decision Aid (DA) with and without an additional Decisional Counseling Program (DCP) for patients being examined for coronary artery ...
(Doctoral thesis / Doktoravhandling, 2021)
Snus is the most commonly used nicotine product among young women in Scandinavia, but the extent of use during pregnancy is less investigated. Normal fetal growth is dependent on a healthy placenta. The possible effects ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Background Unlike pharmacological randomized controlled trials (RCTs), manual-therapy RCTs do not always report adverse events (AEs). The few manual-therapy RCTs that provide information on AEs are frequently without ...
(Doctoral thesis / Doktoravhandling, 2009)
This is the first study in which all physicians were asked to refer all children with suspected arthritis and/or osteomyelitis for follow-up. 20 % of the children with arthritis had Juvenile Idiopathic Arthritis (JIA). Our ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
The aim of this study was to assess the prevalence and risk factors of anal incontinence in an unselected pregnant population at second trimester. A survey of pregnant women attending a routine ultrasound examination was ...
(Doctoral thesis / Doktoravhandling, 2019)
Many patients seeking inpatient treatment for substance use disorders have high levels of severity and often have comorbid mental illness, which can complicate the course of treatment. Up-to-date treatment approaches include ...
(Doctoral thesis / Doktoravhandling, 2009)
The associations between early life lung function and obstructive airway disease and lung function development through childhood are still unsettled. The main aim of the thesis was to determine the overall association ...
(Doctoral thesis / Doktoravhandling, 2022)
In peripheral artery disease (PAD), arterial blood flow to the extremities is impeded. Exposure of the extremity to cyclic pressure changes increases the macro- and micro circulation. This has recently become a treatment ...
(Doctoral thesis / Doktoravhandling, 2012)
Psychological distress is associated with increased risk for incident and recurrent cardiovascular events. Still, the mechanisms are poorly defined, particularly in a community-based setting. Increased systemic inflammation ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
Background Misinterpretation of radiological examinations is an important contributing factor to diagnostic errors. Consultant radiologists in Norwegian hospitals frequently request second reads by colleagues in real time. ...
(Doctoral thesis / Doktoravhandling, 2016)
(Doctoral thesis / Doktoravhandling, 2008)
Despite improvements in detection and treatment of neonatal jaundice, there has been an apparent resurgence of bilirubin-induced brain damage. Unresolved issues concerning bilirubin-induced brain damage include the mechanisms ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
Background: Employment is an important part of recovery for individuals with schizophrenia. The employment rate for this group is as low as 10% in Norway, and major system related barriers to employment are evident.
Aims: ...
(Doctoral thesis / Doktoravhandling, 2023)
Approximately 50% of patients with proximal deep venous thrombosis (DVT) will develop chronic leg problems recognized as post-thrombotic syndrome (PTS). There is no curative treatment, and PTS is associated with increased ...
Changing practices : A practice-based study of cross-disciplinary technology development in hospitals Restricted Access
(Doctoral thesis / Doktoravhandling, 2009)
This study examined why breakthroughs in scientific and technological knowledge may fail to be translated into medical practice. In addition, it supported previous research that has underscored that these failures often ...
(Doctoral thesis / Doktoravhandling, 2017)
(Doctoral thesis / Doktoravhandling, 2008)
Although a number of studies have shown impaired tone and speech sound perception in aphasia, the contribution of these impairments to deficits in auditory language comprehension remains unclear. This study investigates ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
Background. Acute kidney injury (AKI) treated with continuous renal replacement therapy (CRRT) is a severe complication in trauma patients. The aim of the study was to assess primary traumatic injuries and secondary organ ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
Exposure to diesel exhaust particles (DEPs) affects endothelial function and may contribute to the development of atherosclerosis and vasomotor dysfunction. As intracellular calcium concentration [Ca2+]i is considered ...
(Journal article / Tidsskriftartikkel / SubmittedVersion, 2018)
Taurine is regarded as an essential amino acid in utero, and fetal taurine supply is believed to rely solely on placental transfer from maternal plasma. Despite its potential role in intrauterine growth restriction and ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Background
The pathophysiology and outcome of meningococcal septic shock is closely associated with the plasma level of N. meningitidis lipopolysaccharides (LPS, endotoxin) and the circulating level of ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
Ability to anticipate aversive events is important for avoiding dangerous or unpleasant situations. The motivation to avoid an event is influenced by the incentive salience of an event-predicting cue. In an avoidance fMRI ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Background
Treatment services to patients with substance use disorders (SUDs), including those mandated to treatment, needs to be evaluated and evidence based. The Norwegian Municipal Health Care Act (NMHCA) ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Background
Low back pain is common and a significant number of patients experience chronic low back pain. Current treatment options offer small to moderate effects. Patients with vertebral bone marrow ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
Background
Involuntary care and coercive measures are frequently present in mental healthcare for adolescents. The purpose of this study was to examine to what extent adolescents perceive or experience ...
(Journal article / Tidsskriftartikkel / SubmittedVersion, 2017)
Objective: Studies point to white matter (WM) microstructure alterations in both adolescent and adult patients with anorexia nervosa (AN). These include reduced fractional anisotropy in several WM fiber tracts, suggesting ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Background
Well- and dedifferentiated liposarcoma (WD/DDLPS) are rare mesenchymal malignant tumors that account for 20% of all sarcomas in adults. The WD form is a low-grade malignancy with a favourable prognosis which may ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Background & aims: The effect of lycopene-containing foods in prostate cancer development remains undetermined. We tested whether a lycopene-rich tomato intervention could reduce the levels of prostate specific antigen ...
(Doctoral thesis / Doktoravhandling, 2023)
Dementia is a common disease in older people, affecting 50 million individuals worldwide. The most common form, Alzheimer's disease (AD), has no cure due to limited understanding of its causes. In AD, damage to mitochondria ...
(Doctoral thesis / Doktoravhandling, 2018)
Normal fetal growth and development depends on a continuous supply of amino acids. Furthermore, the nutritional environment in which the fetus develops has a major impact on both the immediate and the future health of the ...
(Journal article / Tidsskriftartikkel / SubmittedVersion, 2017)
Background
Patients with inflammatory bowel disease (IBD) are in general prone to weight loss. We explored the risk of inadequate gestational weight gain (GWG), and the impact of GWG on adverse pregnancy outcomes, among ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
Heart rate variability (HRV) refers to various methods of assessing the beat-to-beat variation in the heart over time, in order to draw inference on the outflow of the autonomic nervous system. Easy access to measuring HRV ...
(Doctoral thesis / Doktoravhandling, 2021)
Celiac disease is a chronic inflammatory disorder resulting from mis-appropriate immune response toward ingested glu-ten proteins. Gluten-specific CD4+ T cells, as the key drivers for the pathogenesis can be identified by ...
(Doctoral thesis / Doktoravhandling, 2023)
Primary Hyperparathyroidism (PHPT) is a common endocrine disorder characterized by elevated calcium levels and inappropriately high parathyroid hormone (PTH) levels. Mild PHPT, without apparent symptoms or signs, is now ...
(Doctoral thesis / Doktoravhandling, 2022)
Since its introduction in the 1990s, laparoscopic fundoplication has gradually replaced open fundoplication as the gold standard for surgical treatment of gastroesophageal reflux disease in children. Despite its widespread ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
Background
For injury deaths, the underlying cause of death is defined as the circumstances leading to the injury. When this information is missing, the ICD-10 code X59 (Exposure to unspecified factor) is ...
(Journal article / Tidsskriftartikkel / SubmittedVersion, 2017)
BACKGROUND:
Poor drug adherence is a major cause of apparent treatment-resistant hypertension. As a consequence, several methods have been developed and attempted implemented in clinical practice to reveal non-adherence ...
(Doctoral thesis / Doktoravhandling, 2008)
The prevalence of congestive heart failure (CHF) is increasing dramatically world-wide. Sustained myocardial hypertrophy is an important risk factor for developing CHF, but the underlying mechanisms initiating and maintaining ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
Background
A low physical activity (PA) level in pregnancy is associated with several adverse health outcomes. Early identification of pregnant women at risk of physical inactivity could inform strategies ...
Effects of hypertonic saline on intracranial pressure variables in subarachnoid haemorrhage patients
(Doctoral thesis / Doktoravhandling, 2008)
Elevated intracranial pressure (ICP) and reduced cerebral perfusion pressure (CPP) can be life threatening for patients suffering from acute subarachnoid haemorrhage (SAH). Osmotherapy can be used in these situations. Three ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Background: Adverse media coverage of isolated incidents affects the public perception of the risk of violent behavior among people with mental illness. However, the risk of violence is studied most frequently among ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
Background
It has been suggested that mindfulness is a protective factor that buffers individuals from experiencing severe posttraumatic stress following exposure to a trauma.
We aimed to ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2020)
Background and purpose
β‐Amyloid formation has been suggested to form part of the brain's response to bacterial infection. This hypothesis has been based on experimental animal studies and autopsy studies in humans. We ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Background
Population-based reference data on frequently used questionnaires are important for comparative purposes. Due to changes in health and lifestyles, such data should be updated every other decade. The objectives ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
Background Depression and depressive symptoms are highly prevalent in old persons but are potentially reversible. Full recovery is the main goal in the treatment of depressive episodes. Compared to clinical trials, ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2020)
Background
Mortality rates in COVID‐19 patients in need of mechanical ventilation are high, with wide variations between countries. Most studies were retrospective, and results may not be generalizable due to differences ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Background
Road traffic noise has been associated with adverse health effects including sleep disturbances. Use of sleep medication as an indicator of sleeping problems has rarely been explored in studies ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2012)
Objective To compare the incidence of obstetric anal sphincter injuries (OASIS) in two time periods, before and after implementing a training programme for improved perineal support aimed at reducing the incidence of ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
Background
Changes in Norwegian law and health policy require all health professionals to help safeguard the provision of information and follow-up for the children of parents with mental or physical ...
(Doctoral thesis / Doktoravhandling, 2018)
In forensic genetics, massively parallel sequencing (MPS) has become a realistic alternative to the standard capillary elec-trophoresis. MPS has the potential to both improve DNA-profiling and to provide information beyond ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Objective: Patients with chronic obstructive pulmonary disease (COPD) often have abnormal ECGs. Our aim was to separate the effects on ECG by airway obstruction, emphysema and right ventricular (RV) afterload in patients ...
(Doctoral thesis / Doktoravhandling, 2016)
Employment rates in schizophrenia are consistently low. Considerable research has identified both societal/external barriers and internal, illness related barriers to employment. Neurocognitive impairments are a hallmark ...
(Journal article / Tidsskriftartikkel; Peer reviewed, 2013)
(Journal article / Tidsskriftartikkel / SubmittedVersion, 2017)
Purpose: Circulating chromogranin B (CgB) levels are increased in situations characterized by systemic and myocardial stress, but whether CgB provides prognostic information in patients with acute respiratory failure (ARF) ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
This study assessed the prevalence and risk factors associated with underweight, stunting and wasting among children aged 0–24 months in six districts of Kilimanjaro region, northern Tanzania. A cross-sectional population-based ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
Background
Quality of bystander cardiopulmonary resuscitation (CPR) skills may influence out of hospital cardiac arrest (OHCA) outcomes. We analyzed how the level of CPR training related to indicators of ...
Interplay between the transcription machinery and the responses to DNA damage and replication stress
(Doctoral thesis / Doktoravhandling, 2023)
Human cells are continuously threatened by DNA damage from endogenous sources such as replication stress. To face this threat and prevent cancer, intracellular signaling pathways that promote DNA repair, collectively known ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
Background
Immunochemotherapy, the combined use of immunotherapy and chemotherapy, has demonstrated great promise in several cancers. LTX-315 is an oncolytic peptide with potent immunomodulatory properties ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
The Allergic Rhinitis and its Impact on Asthma (ARIA) initiative commenced during a World Health Organization workshop in 1999. The initial goals were (1) to propose a new allergic rhinitis classification, (2) to promote ...
(Doctoral thesis / Doktoravhandling, 2014)
(Doctoral thesis / Doktoravhandling, 2016)
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2010)
This paper studies the optimum signal choice for the estimation of the aortic blood pressure via aorta radius, using a monostatic radar configuration. The method involves developing the Cramér-Rao lower bound (CRLB) for a ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Cardiac computational models, individually personalized, can provide clinicians with useful diagnosticinformation and aid in treatment planning. A major bottleneck in this process can be determining modelparameters to fit ...
(Doctoral thesis / Doktoravhandling, 2007)
Preeclampsia is complicating 3.7 % of pregnancies, and is defined by hypertension and proteinuria, with signs of endothelial dysfunction, probably caused by placentally derived factors. The fetal consequences of preeclampsia ...
(Doctoral thesis / Doktoravhandling, 2014)
(Doctoral thesis / Doktoravhandling, 2016)
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Background & aims: Bioelectrical impedance analysis (BIA) is an accessible and cheap method to measure fat-free mass (FFM). However, BIA estimates are subject to uncertainty in patient populations with altered body composition ...
(Doctoral thesis / Doktoravhandling, 2012)
Bakgrunn:<br> Behandlingsmuligheter i akuttfasen ved hjerneslag har hatt en positiv utvikling de siste årene. Forebyggende tiltak rettet mot hjerneslag har bidratt til redusert dødelighet, og forekomsten av de med milde ...
(Doctoral thesis / Doktoravhandling, 2022)
The number of young long-term survivors of severe hematological diseases is increasing, due to progress in treatment. However, multiagent chemotherapy regimens and allogeneic hematopoietic stem cell transplantation (allo-HSCT) ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
Background
Early development of an oviparous organism is based on maternally stocked structural, nutritional and regulatory components. These components influence the future developmental potential of an ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
Background
The prevalence of major depression (MD) according to population studies is the same for old (65 years and older) and younger adults. In contrast, an elevated proportion of old MD patients are ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
Ethyl pyruvate (EP) is a simple derivative of pyruvic acid, which is an important endogenous metabolite that can scavenge reactive oxygen species (ROS). Treatment with EP is able to ameliorate systemic inflammation and ...
(Doctoral thesis / Doktoravhandling, 2008)
TITTEL: Effekter av inhalasjonssteroider hos barn og en score for å forutsi senere astma <br><br>
Barnelege og forsker Chandra Sekhar Devulapalli har funnet gunstig effekt av behandling med inhalasjonssteroider (kortison ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
Introduction Roux-en-Y gastric bypass (GBP) is associated with changes in cardiometabolic risk factors and bioavailability of drugs, but whether these changes are induced by calorie restriction, the weight loss or surgery ...
(Doctoral thesis / Doktoravhandling, 2016)
Background: A greater number of individuals are on the move today compared with any other time in human history. The health status of migrants and ethnic minority groups has often been demonstrated to be lower than the ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
Background
Spinal stenosis is a clinical diagnosis in which the main symptom is pain radiating to the lower extremities, or neurogenic claudication. Radiological spinal stenosis is commonly observed in the ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2019)
Genome-wide association studies have transformed psychiatric genetics and provided novel insights into the genetic etiology of psychiatric disorders. Two major discoveries have emerged; the disorders are polygenic, with a ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Computational models of cardiac mechanics, personalized to a patient, offer access to mechanical information above and beyond direct medical imaging. Additionally, such models can be used to optimize and plan therapies ...
Double reading of current chest CT examinations: Clinical importance of changes to radiology reports
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
Objectives Misinterpretation of radiological examinations is an important contributing factor to diagnostic errors. Double reading reduces interpretation errors and increases sensitivity. Consultant radiologists in Norwegian ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
Background
The mucosal changes associated with female genital schistosomiasis (FGS) encompass abnormal blood vessels. These have been described as circular, reticular, branched, convoluted and having uneven calibre. ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Background
Mental health professionals usually decide patients’ access to inpatient care to ensure the rational and fair distribution of care based on need and prognosis. The purpose of the current study ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
Introduction
This study examines factors associated with criminal engagement among patients in opioid maintenance treatment (OMT).
Methods
Questionnaire data recorded annually among 5654 patients in the Norwegian ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
Background
Alterations in autonomic nervous system (ANS) activity might be involved in the pathophysiology of delirium. The aim was to explore autonomic cardiovascular control in older patients with and ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2015)
The atypical antipsychotic drug aripiprazole is a partial dopamine (DA) D2 receptor agonist, which differentiates it from most other antipsychotics. This study compares the brain activation characteristic produced by ...
(Doctoral thesis / Doktoravhandling, 2020)
Cardiovascular disease (CVD) and atherothrombotic events are the major reasons for disability and death in patients with diabetes mellitus (DM). Circulating microvesicles (cMVs), shed from activated cells, have procoagulant ...
(Doctoral thesis / Doktoravhandling, 2013)
Tvangsinnleggelse av pasienter med ruslidelser
Forsker og sykepleier Anne Opsal har i sin studie vist at en stor del av tvangsinnlagte pasienter både etter Psykisk helsevernloven og Helse- og omsorgstjenesteloven har ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Background
Few clinical trials have investigated the prevention of radiographic progression in children with juvenile idiopathic arthritis treated with antirheumatic drugs. This study aimed to investigate ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
Background
A displaced femoral neck fracture (FNF) in patients 55-70 years is a serious injury with a high risk of treatment failure and the optimal surgical treatment remains unclear. We aimed to describe ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
The aim of the present study was to evaluate mortality and functional outcome in old and very old patients with severe traumatic brain injury (TBI) and compare to the predicted outcome according to the internet based CRASH ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
Background and Aims: Whether patients with inflammatory bowel diseases [IBDs] have increased risk of developing cancer has been debated. The aims of the study were to determine the prevalence of intestinal/extraintestinal ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
Objective The subject of research methods is not commonly covered in continuing professional development (CPD) courses in spite of its emphasis in undergraduate education. This initiative aimed to develop postgraduate ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
Background
Crisis Resolution Teams (CRTs) provide short-term intensive home treatment to people experiencing mental health crisis. Trial evidence suggests CRTs can be effective at reducing hospital admissions ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
Objective To determine the effectiveness of the Targeted Interdisciplinary Model for Evaluation and Treatment of Neuropsychiatric Symptoms (TIME) for treatment of moderate to severe agitation in people with dementia. Methods ...
(Doctoral thesis / Doktoravhandling, 2023)
Colorectal cancer patients with inoperable liver metastases have a poor prognosis with an estimated survival of 24-30 months.
Liver transplantation has emerged as a treatment option in recent years, as studies conducted ...