Browsing Institutt for helse og samfunn by Author "Jugessur, Astanand"

Now showing items 1-5 of 5

  • An EPIC predictor of gestational age and its application to newborns conceived by assisted reproductive technologies 
    Haftorn, Kristine L; Lee, Yunsung; Denault, William R P; Page, Christian M; Nustad, Haakon E; Lyle, Robert; Gjessing, Håkon K; Malmberg, Anni; Magnus, Maria C; Næss, Øyvind; Czamara, Darina; Räikkönen, Katri; Lahti, Jari; Magnus, Per; Håberg, Siri E; Jugessur, Astanand; Bohlin, Jon (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    Background Gestational age is a useful proxy for assessing developmental maturity, but correct estimation of gestational age is difficult using clinical measures. DNA methylation at birth has proven to be ...
  • An examination of mediation by DNA methylation on birthweight differences induced by assisted reproductive technologies 
    Carlsen, Ellen Ø.; Lee, Yunsung; Magnus, Per; Jugessur, Astanand; Page, Christian M.; Nustad, Haakon E.; Håberg, Siri E.; Lie, Rolv T.; Magnus, Maria C. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    Background Children born after assisted reproductive technologies (ART) differ in birthweight from those naturally conceived. It has been hypothesized that this might be explained by epigenetic mechanisms. ...
  • Blood-based epigenetic estimators of chronological age in human adults using DNA methylation data from the Illumina MethylationEPIC array 
    Lee, Yunsung; Haftorn, Kristine L; Denault, William R P; Nustad, Haakon E; Page, Christian M; Lyle, Robert; Lee-Ødegård, Sindre; Moen, Gunn-Helen; Prasad, Rashmi B; Groop, Leif C; Sletner, Line; Sommer, Christine; Magnus, Maria C; Gjessing, Håkon K; Harris, Jennifer R; Magnus, Per; Håberg, Siri E; Jugessur, Astanand; Bohlin, Jon (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Background Epigenetic clocks have been recognized for their precise prediction of chronological age, age-related diseases, and all-cause mortality. Existing epigenetic clocks are based on CpGs from the ...
  • Nucleated red blood cells explain most of the association between DNA methylation and gestational age 
    Haftorn, Kristine Løkås; Denault, William Robert Paul; Lee, Yunsung; Page, Christian Magnus; Romanowska, Julia; Lyle, Robert; Næss, Øyvind Erik; Kristjansson, Dana; Magnus, Per Minor; Håberg, Siri Eldevik; Bohlin, Jon; Jugessur, Astanand (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    Determining if specific cell type(s) are responsible for an association between DNA methylation (DNAm) and a given phenotype is important for understanding the biological mechanisms underlying the association. Our EWAS of ...
  • Stability selection enhances feature selection and enables accurate prediction of gestational age using only five DNA methylation sites 
    Haftorn, Kristine L.; Romanowska, Julia; Lee, Yunsung; Page, Christian M.; Magnus, Per M.; Håberg, Siri E.; Bohlin, Jon; Jugessur, Astanand; Denault, William R. P. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    Background DNA methylation (DNAm) is robustly associated with chronological age in children and adults, and gestational age (GA) in newborns. This property has enabled the development of several epigenetic ...