Browsing Institutt for helse og samfunn by Author "Engedal, Knut"
Now showing items 1-20 of 26
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Edwin, Trine Holt; Henjum, Kristi; Nilsson, Lars N. G.; Watne, Leiv; Persson, Karin Ester Torun; Eldholm, Rannveig Sakshaug; Saltvedt, Ingvild; Halaas, Nathalie Bodd; Selbæk, Geir; Engedal, Knut; Strand, Bjørn Heine; Knapskog, Anne Brita (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)Introduction: The progression rate of Alzheimer's disease (AD) varies and might be affected by the triggering receptor expressed on myeloid cells (TREM2) activity. We explored if cerebrospinal fluid (CSF) soluble TREM2 ...
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Eldholm, Rannveig S; Persson, Karin; Barca, Maria L; Knapskog, Anne-Brita; Cavallin, Lena; Engedal, Knut; Selbaek, Geir; Skovlund, Eva; Saltvedt, Ingvild (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)Background Vascular risk factors increase the risk of Alzheimer’s disease (AD), but there is limited evidence on whether comorbid vascular conditions and risk factors have an impact on disease progression. ...
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Bjørkløf, Guro Hanevold; Kirkevold, Marit; Engedal, Knut; Selbæk, Geir; Helvik, Anne-Sofie (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)Articles describing older persons’ experiences of coping with severe depression are, to our knowledge, lacking. This article is methodologically grounded in phenomenological hermeneutics, inspired by Paul Ricoeur, and ...
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Røsvik, Janne-Kathrin; Michelet, Mona; Engedal, Knut; Bergh, Sverre; Bieber, Anja; Gonçalves-Pereira, Manuel; Portolani, Daniel Michael; Hopper, Louise; Irving, Kate; Jelley, Hannah; Kerpershoek, Liselot; Meyer, Gabriele; Marques, Maria J.; Sjölund, Britt-Marie; Sköldunger, Anders; Stephan, Astrid; Verhey, Frans; de Vugt, Marjolein; Woods, Bob; Wolfs, Claire; Zanetti, Orazio; Selbæk, Geir (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)Objectives Home-dwelling people with dementia and their informal carers experience barriers impeding access to community care services. This study is a part of the Actifcare project where eight countries participated. ...
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Fog, Amura F; Straand, Jørund; Engedal, Knut; Blix, Hege S (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)Background Drug consumption increases with age, but there are few comparisons of drug use between old people living at home or in a nursing home. To identify areas of concern as well as in need for quality ...
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Smebye, Kari L; Kirkevold, Marit; Engedal, Knut (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)Background Caring for people with dementia living in their own homes is a challenging care issue that raises ethical dilemmas of how to balance autonomy with their safety and well-being. The theoretical ...
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Tevik, Kjerstin; Selbæk, Geir; Engedal, Knut; Seim, Arnfinn; Krokstad, Steinar; Helvik, Anne-S (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)Background Little is known about factors associated with alcohol consumption and use of drugs with addiction potential in older adults. The aim of this study was to explore the association between ...
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Helvik, Anne-Sofie; Corazzini, Kirsten; Selbæk, Geir; Björklöf, Guro Hanevold; Laks, Jerson; Saltyte Benth, Jurate; Østbye, Truls; Engedal, Knut (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)Background Knowledge about long-term change in health related quality of life (HQoL) among older adults after hospitalization for treatment of depression has clinical relevance. The aim was firstly to describe the change ...
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Smebye, Kari L; Kirkevold, Marit; Engedal, Knut (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2012)Background Many countries have passed laws giving patients the right to participate in decisions about health care. People with dementia cannot be assumed to be incapable of making decisions on their diagnosis ...
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Tangen, Gro Gujord; Bergland, Astrid; Engedal, Knut; Mengshoel, Anne Marit (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2016)Parkinsonian signs are common in patients with Alzheimer’s disease (AD) of mild degree and predict functional decline, but their relationship with gait speed and balance is unclear. The aims of this study were to describe ...
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Mjørud, Marit; Engedal, Knut; Røsvik, Janne; Kirkevold, Marit (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)Background Persons with dementia have described life in nursing home as difficult and lonely. Persons with dementia often reside in nursing homes for several years; therefore, knowledge is needed about how ...
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Witoelar, Aree; Rongve, Arvid; Almdahl, Ina Selseth; Ulstein, Ingun; Engvig, Andreas; White, Linda Rosemary; Selbæk, Geir; Stordal, Eystein; Andersen, Fredrik; Brækhus, Anne; Saltvedt, Ingvild; Engedal, Knut; Hughes, Timothy; Bergh, Sverre; Bråthen, Geir; Bogdanovic, Nenad; Bettella, Francesco; Wang, Yunpeng; Athanasiu, Lavinia; Bahrami, Shahram; Le Hellard, Stephanie; Giddaluru, Sudheer; Dale, Anders M; Sando, Sigrid Botne; Steinberg, Stacy; Stefansson, Hreinn; Snaedal, Jon; Desikan, Rahul S; Stefansson, Kari; Aarsland, Dag; Djurovic, Srdjan; Fladby, Tormod; Andreassen, Ole Andreas (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)A large fraction of genetic risk factors for Alzheimer’s Disease (AD) is still not identified, limiting the understanding of AD pathology and study of therapeutic targets. We conducted a genome-wide association study (GWAS) ...
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Tevik, Kjerstin Elisabeth; Selbæk, Geir; Engedal, Knut; Seim, Arnfinn; Krokstad, Steinar; Helvik, Anne-Sofie (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)Background The aim of this study was to investigate whether frequent drinking, use of drugs with addiction potential and the possible combination of frequent drinking and use of prescribed drugs with addiction potential ...
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Persson, Karin; Eldholm, Rannveig Sakshaug; Barca, Maria Lage; Cavallin, Lena; Ferreira, Daniel; Knapskog, Anne Brita; Selbæk, Geir; Brækhus, Anne; Saltvedt, Ingvild; Westman, Eric; Engedal, Knut (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)Background/Aims MRI assessment of the brain has demonstrated four different patterns of atrophy in patients with Alzheimer’s disease dementia (AD): typical AD, limbic-predominant AD, hippocampal-sparing AD, and a subtype ...
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Edwin, Trine Holt; Strand, Bjørn Heine; Persson, Karin Ester Torun; Engedal, Knut; Selbæk, Geir; Knapskog, Anne Brita (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)Objectives Neuropsychiatric symptoms (NPS) are associated with dementia severity and progression rate. NPS clusters have different neurobiological underpinnings; therefore, their effect on dementia progression may differ. ...
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Helvik, Anne-Sofie; Šaltytė Benth, Jūratė; Wu, Bei; Engedal, Knut; Selbæk, Geir (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)Background The prevalence of psychotropic drug (PTD) use in NH residents is high, but few have explored prevalence and persistency in PTD in NH residents and factors associated with persistency. This at the ...
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Røen, Irene Mari; Selbæk, Geir; Kirkevold, Øyvind; Engedal, Knut; Testad, Ingelin; Bergh, Sverre (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)Background Earlier studies of nursing home patients show a high prevalence of dementia, neuropsychiatric symptoms (NPS), pain, and dependency in activities of daily living. The REDIC-NH cohort was set up to study the ...
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Strandenæs, Margit Gausdal; Lund, Anne; Engedal, Knut; Kirkevold, Øyvind; Selbæk, Geir; Saltyte Benth, Jurate; Rokstad, Anne Marie Mork (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)The objectives of the study were (a) to compare self-reported Quality of Life (QoL) in a 24-month follow-up of people with dementia attending day care designed for people with dementia (day-care group, DC) with people with ...
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Helvik, Anne-Sofie; Engedal, Knut; Wu, Bei; Saltyte Benth, Jurate; Corazzini, Kirsten; Røen, Irene Mari; Selbæk, Geir (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)We aimed at assessing time shift in the severity of neuropsychiatric symptoms (NPS) in nursing home residents between 2004/2005 and 2010/2011 and associations between NPS and socio-demographic variables, physical health ...
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Tangen, Gro Gujord; Engedal, Knut; Bergland, Astrid; Moger, Tron Anders; Hansson, Oskar; Mengshoel, Anne Marit (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2015)Background: Impaired spatial navigation is an early sign of Alzheimer's disease (AD), but this can be difficult to assess in clinical practice. We examined how the performance on the Floor Maze Test (FMT), which combines ...