Browsing Institutt for helse og samfunn by Author "Edwin, Trine Holt"

Now showing items 1-5 of 5

  • A high cerebrospinal fluid soluble TREM2 level is associated with slow clinical progression of Alzheimer's disease 
    Edwin, Trine Holt; Henjum, Kristi; Nilsson, Lars N. G.; Watne, Leiv; Persson, Karin Ester Torun; Eldholm, Rannveig Sakshaug; Saltvedt, Ingvild; Halaas, Nathalie Bodd; Selbæk, Geir; Engedal, Knut; Strand, Bjørn Heine; Knapskog, Anne Brita (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Introduction: The progression rate of Alzheimer's disease (AD) varies and might be affected by the triggering receptor expressed on myeloid cells (TREM2) activity. We explored if cerebrospinal fluid (CSF) soluble TREM2 ...
  • Comparison of cerebrospinal fluid amyloidogenic nanoplaques with core biomarkers of Alzheimer's disease 
    Aksnes, Mari; Tiiman, Ann; Edwin, Trine Holt; Terenius, Lars; Bogdanovic, Nenad; Vukojevic, Vladana; Knapskog, Anne Brita (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    Accurate biomarkers of Alzheimer’s disease (AD) are essential for early diagnosis and intervention. Available biomarkers are not sufficient to permit the monitoring of AD progression over time, and additional biomarkers ...
  • Evaluation of semi-quantitative measures of 18F-Flutemetamol PET for the clinical diagnosis of Alzheimer’s disease 
    Müller, Ebba Gløersen; Stokke, Caroline; Stokmo, Henning Langen; Edwin, Trine Holt; Knapskog, Anne Brita; Rootwelt-Revheim, Mona Elisabeth (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    Background: 18F-flutemetamol positron emission tomography (PET) is used to assess cortical amyloid-β burden in patients with cognitive impairment to support a clinical diagnosis. Visual classification is the most widely ...
  • Neuropsychiatric symptoms and comorbidity: Associations with dementia progression rate in a memory clinic cohort 
    Edwin, Trine Holt; Strand, Bjørn Heine; Persson, Karin Ester Torun; Engedal, Knut; Selbæk, Geir; Knapskog, Anne Brita (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    Objectives Neuropsychiatric symptoms (NPS) are associated with dementia severity and progression rate. NPS clusters have different neurobiological underpinnings; therefore, their effect on dementia progression may differ. ...
  • Time from dementia diagnosis to nursing-home admission and death among persons with dementia: A multistate survival analysis 
    Mjørud, Marit; Selbæk, Geir; Bjertness, Espen; Edwin, Trine Holt; Engedal, Knut; Knapskog, Anne Brita; Strand, Bjørn Heine (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Objectives: To estimate transition times from dementia diagnosis to nursing-home (NH) admission or death and to examine whether sex, education, marital status, level of cognitive impairment and dementia aetiology are ...