Browsing Institutt for helse og samfunn by Author "Celius, Elisabeth Gulowsen"

Now showing items 1-12 of 12

  • A systems biology approach uncovers cell-specific gene regulatory effects of genetic associations in multiple sclerosis. 
    Madireddy, L; Patsopoulos, NA; Cotsapas, C; Bos, Steffan Daniel; Beecham, Ashley; McCauley, J; Kim, K; Jia, X; Santaniello, A; Caillier, SJ; Andlauer, TFM; Barcellos, Lisa; Berge, Tone; Bernardinelli, L; Martinelli-Boneschi, F; Booth, D; Briggs, Farren; Celius, Elisabeth Gulowsen; Comabella, M; Comi, G; Cree, BAC; D'Alfonso, S; Dedham, K; Duquette, P.; Dardiotis, E; Esposito, F; Gasperi, Christiane; Goris, A; Dubois, B; Gourraud, PA; Hadjigeorgiou, GM; Haines, J; Hawkins, C; Hemmer, B; Hintzen, R; Horakova, D; Isobe, N; Kalra, S; Kira, Jun-ichi; Khalil, M; Kockum, I; Lill, CM; Lincoln, Michelle; Luessi, F; Martin, R; Oturai, A; Palotie, A; Pericak-Vance, MA; Henry, R; Saarela, J; Ivinson, Adrian; Olsson, Thomas; Taylor, Bruce; Stewart, GJ; Harbo, Hanne Flinstad; Compston, A; Hauser, SL; Hafler, DA; Zipp, F; De Jager, P; Sawcer, S; Oksenberg, JR; Baranzini, SE (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    Genome-wide association studies (GWAS) have identified more than 50,000 unique associations with common human traits. While this represents a substantial step forward, establishing the biology underlying these associations ...
  • DNA methylation as a mediator of HLA-DRB1 15:01 and a protective variant in multiple sclerosis 
    Kular, Lara; Liu, Yun; Ruhrmann, Sabrina; Zheleznyakova, Galina; Marabita, Francesco; Gomez-Cabrero, David; James, Tojo; Ewing, Ewoud; Lindén, Magdalena; Górnikiewicz, Bartosz; Aeinehband, Shahin; Stridh, Pernilla; Link, Jenny; Andlauer, Till F.M.; Gasperi, Christiane; Wiendl, Heinz; Zipp, Frauke; Gold, Ralf; Tackenberg, Björn; Weber, Frank; Hemmer, Bernhard; Strauch, Konstantin; Heilmann-Heimbach, Stefanie; Rawal, Rajesh; Schminke, Ulf; Schmidt, Carsten O.; Kacprowski, Tim; Franke, Andre; Laudes, Matthias; Dilthey, Alexander T.; Celius, Elisabeth Gulowsen; Søndergaard, Helle Bach; Tegnér, Jesper; Harbo, Hanne Flinstad; Oturai, Annette B.; Olafsson, Sigurgeir; Eggertsson, Hannes P.; Halldorsson, Bjarni V.; Hjaltason, Haukur; Olafsson, Elias; Jonsdottir, Ingileif; Stefansson, Kari; Olsson, Tomas; Piehl, Fredrik; Ekström, Tomas J.; Kockum, Ingrid; Feinberg, Andrew P.; Jagodic, Maja (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    The human leukocyte antigen (HLA) haplotype DRB1*15:01 is the major risk factor for multiple sclerosis (MS). Here, we find that DRB1*15:01 is hypomethylated and predominantly expressed in monocytes among carriers of ...
  • Fatigue in multiple sclerosis is associated with socioeconomic factors 
    Broch, Line; Flemmen, Heidi Øyen; Simonsen, Cecilia Smith; Berg-Hansen, Pål; Ormstad, Heidi; Brunborg, Cathrine; Celius, Elisabeth Gulowsen (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    Objectives: Fatigue is one of the leading causes of reduced quality of life and inability to work in people with multiple sclerosis (pwMS). Currently, no treatment effectively ameliorates fatigue. We still know little about ...
  • High prevalence of fatigue in contemporary patients with multiple sclerosis 
    Broch, Line; Simonsen, Cecilia Smith; Flemmen, Heidi Øyen; Berg-Hansen, Pål; Skardhamar, Åshild; Ormstad, Heidi; Celius, Elisabeth Gulowsen (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    Objective: The prevalence of multiple sclerosis (MS)-related fatigue may have changed due to new diagnostic criteria and new disease modifying drugs. We aimed to assess the prevalence of fatigue in a contemporary MS cohort, ...
  • Increased DNA methylation of SLFN12 in CD4+ and CD8+ T cells from multiple sclerosis patients 
    Rhead, Brooke; Brorson, Ina Skaara; Berge, Tone; Adams, Cameron; Quach, Hong; Moen, Stine Marit; Berg-Hansen, Pål; Celius, Elisabeth Gulowsen; Sangurdekar, Dipen; Bronson, Paola G.; Lea, Rodney A.; Burnard, Sean; Maltby, Vicky E.; Scott, Rodney J; Lechner-Scott, Jeannette; Harbo, Hanne Flinstad; Bos, Steffan Daniel; Barcellos, Lisa F (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    DNA methylation is an epigenetic mark that is influenced by environmental factors and is associated with changes to gene expression and phenotypes. It may link environmental exposures to disease etiology or indicate important ...
  • Level of education and multiple sclerosis risk over a 50-year period: Registry-based sibling study 
    Bjørnevik, Kjetil; Riise, Trond; Benjaminsen, Espen; Celius, Elisabeth Gulowsen; Dahl, Ole-Petter; Kampman, Margitta Theodora; Løken-Amsrud, Kristin Ingeleiv; Midgard, Rune; Myhr, Kjell-Morten; Torkildsen, Øivind; Vatne, Anita; Grytten, Nina (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
    Background: The conflicting results from studies on socioeconomic status (SES) and multiple sclerosis (MS) risk might be due to a change in the distribution of environmental exposures over time or to methodological limitations ...
  • Magnetic resonance imaging perfusion is associated with disease severity and activity in multiple sclerosis 
    Sowa, Piotr; Nygaard, Gro Owren; Bjørnerud, Atle; Celius, Elisabeth Gulowsen; Harbo, Hanne Finstad; Beyer, Mona Kristiansen (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
    Purpose The utility of perfusion weighted imaging in multiple sclerosis (MS) is not well investigated. The purpose of this study was to compare baseline normalized perfusion measures in subgroups of newly diagnosed MS ...
  • Maternal education has significant influence on progression in multiple sclerosis 
    Flemmen, Heidi Øyen; Simonsen, Cecilia Smith; Broch, Line; Brunborg, Cathrine; Berg-Hansen, Pål; Moen, Stine Marit; Kersten, Hege; Celius, Elisabeth Gulowsen (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    Objective: The identification of potential risk factors for disease severity is of great importance in the treatment of multiple sclerosis. The influence of socioeconomic status on progression in multiple sclerosis (MS) ...
  • Migraine and frequent tension-type headache are not associated with multiple sclerosis in a Norwegian case-control study 
    Gustavsen, Marte Wendel; Celius, Elisabeth Gulowsen; Winsvold, Bendik K S; Moen, Stine Marit; Nygaard, Gro Owren; Berg-Hansen, Pål; Lie, Benedicte Alexandra; Zwart, John-Anker; Harbo, Hanne Flinstad (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
    Background Inconsistent results have been obtained with regard to headache comorbidity in multiple sclerosis (MS). Objective Investigate the one-year prevalence of migraine and tension-type headache (TTH) in Norwegian MS ...
  • Prevalence of multiple sclerosis in rural and urban districts in Telemark county, Norway 
    Flemmen, Heidi Øyen; Simonsen, Cecilia Smith; Berg-Hansen, Pål; Moen, Stine Marit; Kersten, Hege; Heldal, Kristian; Celius, Elisabeth Gulowsen (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Objective: To explore the trends in prevalence and incidence of multiple sclerosis (MS) in Telemark, Norway (latitude 58.7-60.3˚N), over the past two decades, with focus on differences between rural and urban areas. Methods: ...
  • The course of multiple sclerosis rewritten: a Norwegian population-based study on disease demographics and progression 
    Simonsen, Cecilia Smith; Flemmen, Heidi Øyen; Broch, Line; Brunborg, Cathrine; Berg-Hansen, Pål; Moen, Stine Marit; Celius, Elisabeth Gulowsen (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Objectives: Over the past few decades, there has been an improvement in the rate of disability progression in multiple sclerosis (MS) patients, and most studies relate this evolvement to the introduction of disease-modifying ...
  • The influence of THC:CBD oromucosal spray on driving ability in patients with multiple sclerosis-related spasticity 
    Celius, Elisabeth Gulowsen; Vila, Carlos (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    Background: Driving ability is a key function for the majority of patients with multiple sclerosis (MS) to help maintain daily interactions. Both physical and cognitive disability, as well as treatments, may affect the ...