Browsing Institutt for helse og samfunn by Author "Aseffa, Abraham"

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  • Molecular studies of meningococcal and pneumococcal meningitis patients in Ethiopia 
    Mihret, Wude; Brusletto, Berit Sletbakk; Øvstebø, Reidun; Siebke, Anne-Marie; Norheim, Gunnstein; Merid, Yared; Kassu, Afework; Abebe, Workeabeba; Ayele, Samuel; Silamsaw, Mezgebu; Yamuah, Lawrence; Aseffa, Abraham; Petros, Beyene; Caugant, Dominique A; Brandtzaeg, Petter (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    Neisseria meningitidis infections in sub-Saharan Africa usually present with distinct symptoms of meningitis but very rarely as fulminant septicemia when reaching hospitals. In Europe, development of persistent meningococcal ...
  • Salivary and serum antibody response against Neisseria meningitidis after vaccination with conjugate polysaccharide vaccines in Ethiopian volunteers 
    Bårnes, Guro Kristine; Workalemahu, Bereket; Kristiansen, Paul Arne; Beyene, Demissew Balcha; Merdekios, Behailu; Fissiha, P.; Aseffa, Abraham; Caugant, Dominique A; Næss, Lisbeth Meyer (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
    Meningococcal conjugate vaccines induce serum antibodies crucial for protection against invasive disease. Salivary antibodies are believed to be important for hindering meningococcal acquisition and/or clearance of established ...
  • Surveillance of bacterial meningitis, Ethiopia, 2012–2013 
    Mihret, Wude; Lema, Tsehaynesh; Merid, Yared; Kassu, Afework; Abebe, Workeabeba; Moges, Beyene; Tenna, Admasu; Woldegebriel, Fitsum; Yidnekachew, Melaku; Mekonnen, Wondale; Yamuah, Lawrence; Ahmed, Arslan; Silamsaw, Mezgebu; Petros, Beyene; Oksnes, Jan; Rosenqvist, Einar; Ayele, Samuel; Caugant, Dominique A; Aseffa, Abraham; Norheim, Gunnstein (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
    Ethiopia has the second-largest population (≈94 million in 2013) among the meningitis belt countries of sub-Saharan Africa (1). However, during 2001–2010, a median of only 1,056 suspected meningitis cases per year (range ...
  • Whole genome sequencing reveals within-host genetic changes in paired meningococcal carriage isolates from Ethiopia 
    Bårnes, Guro Kristine; Brynildsrud, Ola Brønstad; Børud, Bente; Workalemahu, Bereket; Kristiansen, Paul Arne; Beyene, Demissew; Aseffa, Abraham; Caugant, Dominique A (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    Background: Meningococcal colonization is a prerequisite for transmission and disease, but the bacterium only very infrequently causes disease while asymptomatic carriage is common. Carriage is highly dynamic, showing a ...