Browsing Institutt for helse og samfunn by Author "Abebe, Fekadu"
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Abebe, Fekadu; Belay, Mulugeta; Legesse, Mengistu; Mihret, Adane; Franken, Kees L (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)Mycobacterium tuberculosis (Mtb) early secreted protein antigen 6 (ESAT‐6) and culture filtrate protein 10 (CFP‐10) are among candidate vaccines against tuberculosis (TB). Results of experimental animal models show that ...
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Gele, Abdikadir Ali; Sagbakken, Mette; Abebe, Fekadu; Bjune, Gunnar Aksel (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2010)Background At the dawn of the third millennium, while the control of the second biggest infectious killer in the world (tuberculosis [TB]) is an international priority, millions of pastoralist communities in the Horn of ...
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Legesse, Mengistu; Ameni, Gobena; Mamo, Gezahegne; Medhin, Girmay; Bjune, Gunnar; Abebe, Fekadu (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2011)Background There is little information concerning community-based prevalence of latent tuberculosis infection (LTBI) using T-cell based interferon-γ (IFN-γ) release assays (IGRAs), particularly in TB endemic ...
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Belay, Mulugeta; Bjune, Gunnar; Ameni, Gobena; Abebe, Fekadu (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2012)Background TB is a major public health problem globally and Ethiopia is 8th among the 22 high burden countries. Early detection and effective treatment are pre-requisites for a successful TB control programme. ...
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Sima, Bezawit T; Belachew, Tefera; Abebe, Fekadu (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)Background Tuberculosis (TB) remains the prime killer disease among infectious diseases. TB control depends on early case detection and treatment in a directly observed treatment short course (DOTS) programme. ...
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Abebe, Fekadu; Belay, Mulugeta; Legesse, Mengistu; Franken, Kees LMC; Ottenhoff, Tom HM (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)As part of a major project to investigate protective and diagnostic immune markers against tuberculosis (TB), we measured antibody isotype responses to Mycobacterium tuberculosis (Mtb) antigens (LAM, Rv2031, and HBHA) in ...
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Legesse, Mengistu; Ameni, Gobena; Mamo, Gezahegne; Medhin, Girmay; Shawel, Dawit; Bjune, Gunnar; Abebe, Fekadu (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2010)Background Afar pastoralists live in the northeast of Ethiopia, confined to the most arid part of the country, where there is least access to educational, health and other social services. Tuberculosis (TB) ...
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Legesse, Mengistu; Ameni, Gobena; Mamo, Gezahegne; Medhin, Girmay; Bjune, Gunnar; Abebe, Fekadu (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2011)Background Infection with Mycobacterium bovis (Mb) predominantly causes cervical TB lymphadenitis (TBL). Raw milk is considered the main source of Mb infection and raw milk is a major food source for Afar ...
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Sima, Bezawit Temesgen; Belachew, Tefera; Abebe, Fekadu (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)BACKGROUND: Ethiopia is ninth among the world high tuberculosis (TB) burden countries, pastoralists being the most affected population. However, there is no published report whether the behavior related to TB are different ...
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Biffa, Demelash; Skjerve, Eystein; Oloya, James; Bogale, Asseged; Abebe, Fekadu; Dahle, Ulf; Bohlin, Jon; Djønne, Berit (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2010)Background Bovine Tuberculosis (BTB) is a widespread and endemic disease of cattle in Ethiopia. Information relating to genotypic characteristics of Mycobacterium bovis strains affecting the cattle population ...
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Legesse, Mengistu; Ameni, Gobena; Mamo, Gezahegne; Medhin, Girmay; Bjune, Gunnar; Abebe, Fekadu (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2010)Background Currently, T-cell based gamma interferon (IFNγ) release assays (IGRAs) are acknowledged as the best methods available for the screening of latent tuberculosis infection (LTBI) and also as aid for ...
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Belay, Mulugeta; Legesse, Mengistu; Mihret, Adane; Ottenhoff, Tom HM; Franken, Kees Lumc; Bjune, Gunnar Aksel; Abebe, Fekadu (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)Tuberculosis (TB) is among the leading causes of morbidity and mortality. The causative agent, Mycobacterium tuberculosis (Mtb), has evolved virulent factors for entry, survival, multiplication and immune evasion. Rv2031 ...
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Belay, Mulugeta; Legesse, Mengistu; Dagne, Daniel; Mihret, Adane; Bekele, Yonas; Medhin, Girmay; Bjune, Gunnar; Abebe, Fekadu (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)Background QuantiFERON-TB Gold In-Tube® (QFT-GIT) test is used for the diagnosis of latent tuberculosis (TB) infection. Besides, QFT-GIT test could allow tracking changes in immune response among TB patients ...
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Sima, Bezawit T; Belachew, Tefera; Bjune, Gunnar; Abebe, Fekadu (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)Background Pastoralists rely on traditional healers (THs) for general health problems. However, some studies indicate that such practices result in delays in the diagnosis and treatment of tuberculosis (TB) ...
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Belay, Mulugeta; Bjune, Gunnar Aksel; Abebe, Fekadu (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)Background: TB-HIV co-infection is one of the biggest public health challenges in sub-Saharan Africa. Although there is a wealth of information on TB-HIV co-infection among settled populations in Africa and elsewhere, to ...