Finn forfatter "Pandya, Abhilash D."

Viser treff 1-6 av 6

  • Biodistribution of Poly(alkyl cyanoacrylate) Nanoparticles in Mice and Effect on Tumor Infiltration of Macrophages into a Patient-Derived Breast Cancer Xenograft 
    Pandya, Abhilash D.; Iversen, Tore Geir; Moestue, Siver Andreas; Grinde, Maria Tunset; Mørch, Ýrr Asbjørg; Snipstad, Sofie; Åslund, Andreas; Øy, Geir Frode; Kildal, Wanja; Engebråten, Olav; Sandvig, Kirsten; Skotland, Tore; Mælandsmo, Gunhild Mari (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    We have investigated the biodistribution and tumor macrophage infiltration after intravenous injection of the poly(alkyl cyanoacrylate) nanoparticles (NPs): PEBCA (poly(2-ethyl-butyl cyanoacrylate), PBCA (poly(n-butyl ...
  • Cabazitaxel-loaded Poly(2-ethylbutyl cyanoacrylate) nanoparticles improve treatment efficacy in a patient derived breast cancer xenograft. 
    Fusser, Markus; Øverbye, Anders; Pandya, Abhilash D.; Mørch, Ýrr Asbjørg; Borgos, Sven Even F.; Kildal, Wanja; Snipstad, Sofie; Sulheim, Einar; Fleten, Karianne Giller; Askautrud, Hanne Arenberg; Engebraaten, Olav; Flatmark, Kjersti; Iversen, Tore Geir; Sandvig, Kirsten; Skotland, Tore; Mælandsmo, Gunhild Mari (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    The effect of poly(2-ethyl-butyl cyanoacrylate) nanoparticles containing the cytotoxic drug cabazitaxel was studied in three breast cancer cell lines and one basal-like patient-derived xenograft model grown in the mammary ...
  • Drug-Loaded Photosensitizer-Chitosan Nanoparticles for Combinatorial Chemo- and Photodynamic-Therapy of Cancer 
    Pandya, Abhilash D.; Øverbye, Anders; Saharia, Priyanka; Gaware, Vivek S.; Høgset, Håkon; Masson, Már; Høgset, Anders; Mælandsmo, Gunhild Mari; Skotland, Tore; Sandvig, Kirsten; Iversen, Tore Geir (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    In this study we have developed biodegradable polymeric nanoparticles (NPs) containing the cytostatic drugs mertansine (MRT) or cabazitaxel (CBZ). The NPs are based on chitosan (CS) conjugate polymers synthesized with ...
  • Mechanism of cellular uptake and cytotoxicity of paclitaxel loaded lipid nanocapsules in breast cancer cells. 
    Valsalakumari, Remya; Yadava, Sunil Kumar; Szwed, Marzena; Pandya, Abhilash D.; Mælandsmo, Gunhild M.; Torgersen, Maria Lyngaas; Iversen, Tore Geir; Skotland, Tore; Sandvig, Kirsten; Giri, Jyotsnendu (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2021)
    Lipid nanocapsules (LNCs) have proven their efficacy in delivering different drugs to various cancers, but no studies have yet described their uptake mechanisms, paclitaxel (PTX) delivery or resulting cytotoxicity towards ...
  • Paclitaxel-loaded biodegradable ROS-sensitive nanoparticles for cancer therapy. 
    Pandya, Abhilash D.; Jager, Eliezer; Fam, Shahla Bagheri; Höcherl, Anita; Jäger, Alessandro; Sincari, Vladimir; Nyström, Bo; Stepanek, Petr; Skotland, Tore; Sandvig, Kirsten; Hrubý, Martin; Mælandsmo, Gunhild Mari (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    Background: Reactive oxygen species (ROS), such as hydrogen peroxide and superoxide, trigger biodegradation of polymer-based nanoparticles (NPs) bearing pinacol-type boronic ester groups. These NPs may selectively release ...
  • Physicochemical characterization, toxicity and in vivo biodistribution studies of a discoidal, lipid-based drug delivery vehicle: Lipodisq nanoparticles containing doxorubicin 
    Torgersen, Maria Lyngaas; Judge, Peter J.; Bada Juarez, Juan F.; Pandya, Abhilash D.; Fusser, Markus; Davies, Charlie W.; Maciejewska, Matylda K.; Yin, Daniel J.; Mælandsmo, Gunhild Mari; Skotland, Tore; Watts, Anthony; Sandvig, Kirsten (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Many promising pharmaceutically active compounds have low solubility in aqueous environments and their encapsulation into efficient drug delivery vehicles is crucial to increase their bioavailability. Lipodisq nanoparticles ...