Browsing Institutt for biovitenskap by Title

Now showing items 64-83 of 171

  • Gastrointestinal microbial community changes in Atlantic cod (Gadus morhua) exposed to crude oil 
    Bagi, Andrea; Riiser, Even S; Molland, Hilde S; Star, Bastiaan; Haverkamp, Thomas H A; Sydnes, Magne O; Pampanin, Daniela M (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    Background The expansion of offshore oil exploration increases the risk of marine species being exposed to oil pollution in currently pristine areas. The adverse effects of oil exposure through toxic ...
  • Gene pleiotropy constrains gene expression changes in fish adapted to different thermal conditions 
    Papakostas, Spiros; Vøllestad, Leif Asbjørn; Bruneaux, Matthieu; Aykanat, Tutku; Vanoverbeke, Joost; Ning, Mei; Primmer, Craig R.; Leder, Erica H. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
    Understanding the factors that shape the evolution of gene expression is a central goal in biology, but the molecular mechanisms behind this remain controversial. A related major goal is ascertaining how such factors may ...
  • Genetic and morphometric divergence in threespine stickleback in the Chignik catchment, Alaska 
    Taugbøl, Annette; Junge, Claudia; Quinn, Thomas P.; Herland, Anders; Vøllestad, Leif Asbjørn (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
    Divergent selection pressures induced by different environmental conditions typically lead to variation in life history, behavior, and morphology. When populations are locally adapted to their current environment, selection ...
  • Genomic architecture of haddock (Melanogrammus aeglefinus) shows expansions of innate immune genes and short tandem repeats 
    Tørresen, Ole K; Brieuc, Marine S O; Solbakken, Monica H; Sørhus, Elin; Nederbragt, Alexander J; Jakobsen, Kjetill S; Meier, Sonnich; Edvardsen, Rolf B; Jentoft, Sissel (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    Background Increased availability of genome assemblies for non-model organisms has resulted in invaluable biological and genomic insight into numerous vertebrates, including teleosts. Sequencing of the ...
  • Genomic Differentiation and Demographic Histories of Atlantic and Indo-Pacific Yellowfin Tuna (Thunnus albacares) Populations 
    Barth, Julia Maria Isis; Damerau, Malte; Matschiner, Michael; Jentoft, Sissel; Hanel, Reinhold (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    Recent developments in the field of genomics have provided new and powerful insights into population structure and dynamics that are essential for the conservation of biological diversity. As a commercially highly valuable ...
  • The Genomics of Hybrid Speciation 
    Trier, Cassandra Nicole (Doctoral thesis / Doktoravhandling, 2018)
    The genomic landscape of a hybrid species is marked by alternating regions of parental inheritance and areas of genomic constraint which form reproductive barriers. A PhD candidate at the University of Oslo has explored ...
  • Good enough practices in scientific computing 
    Wilson, Greg; Brian, Jennifer; Cranston, Karen; Kitzes, Justin; Nederbragt, Alexander Johan; Teal, Tracy K (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    Computers are now essential in all branches of science, but most researchers are never taught the equivalent of basic lab skills for research computing. As a result, data can get lost, analyses can take much longer than ...
  • GSuite HyperBrowser: integrative analysis of dataset collections across the genome and epigenome 
    Simovski, Boris; Vodak, Daniel; Gundersen, Sveinung; Domanska, Diana Ewa; Azab, Abdulrahman; Holden, Lars; Holden, Marit; Grytten, Ivar; Rand, Knut Dagestad; Drabløs, Finn Sverre; Johansen, Morten; Mora, Antonio M.; Lund-Andersen, Christin; Fromm, Bastian; Eskeland, Ragnhild; Gabrielsen, Odd Stokke; Ferkingstad, Egil; Nakken, Sigve; Bengtsen, Mads; Nederbragt, Alexander Johan; Thorarensen, Hildur Sif; Andreas Akse, Johannes; Glad, Ingrid Kristine; Hovig, Johannes Eivind; Sandve, Geir Kjetil (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    Background: Recent large-scale undertakings such as ENCODE and Roadmap Epigenomics have generated experimental data mapped to the human reference genome (as genomic tracks) representing a variety of functional elements ...
  • Hepatic FcRn regulates albumin homeostasis and susceptibility to liver injury 
    Pyzik, Michal; Rath, Timo; Kuo, Timothy T.; Win, Sanda; Baker, Kristi; Hubbard, Jonathan J.; Grenha, Rosa; Gandhi, Amit; Krämer, Thomas D.; Mezo, Adam R.; Taylo, Zachary S.; McDonnell, Kevin; Nienaber, Vicki; Andersen, Jan Terje; Mizoguchi, Atsushi; Blumberg, Laurence; Purohit, Shalaka; Jones, Susan D.; Christianson, Gregory J.; Lencer, Wayne I.; Sandlie, Inger; Kaplowitz, Neil; Roopenian, Derry C.; Blumberg, Richard S. (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
    The neonatal crystallizable fragment receptor (FcRn) is responsible for maintaining the long half-life and high levels of the two most abundant circulating proteins, albumin and IgG. In the latter case, the protective ...
  • How can we quantify impacts of contaminants in marine ecosystems? The ICON project 
    Hylland, Ketil; Burgeot, Thierry; Martínez-Gómez, Concepción; Lang, Thomas; Robinson, Craig D.; Svavarsson, Jörundur; Thain, John E.; Vethaak, A. Dick; Gubbins, Matthew J. (Journal article / Tidsskriftartikkel / SubmittedVersion, 2017)
    An international workshop on marine integrated contaminant monitoring (ICON) was organised to test a framework on integrated environmental assessment and simultaneously assess the status of selected European marine areas. ...
  • How to take autophagy and endocytosis up a notch 
    Barth, Julia Maria Isis; Köhler, Katja (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
    The interconnection of the endocytic and autophagosomal trafficking routes has been recognized more than two decades ago with both pathways using a set of identical effector proteins and sharing the same ultimate lysosomal ...
  • A human endothelial cell-based recycling assay for screening of FcRn targeted molecules 
    Grevys, Algirdas; Nilsen, Jeannette; Sand, Kine Marita Knudsen; Daba, Muluneh Bekele; Øynebråten, Inger; Bern, Malin C.; McAdam, Martin Berner; Foss, Stian; Schlothauer, Tilman; Michaelsen, Terje Einar; Christianson, Gregory J.; Roopenian, Derry C.; Blumberg, Richard S.; Sandlie, Inger; Andersen, Jan Terje (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    Albumin and IgG have remarkably long serum half-lives due to pH-dependent FcRn-mediated cellular recycling that rescues both ligands from intracellular degradation. Furthermore, increase in half-lives of IgG and albumin-based ...
  • Igs as substrates for transglutaminase 2: Implications for autoantibody production in celiac disease 
    Iversen, Rasmus; Fleur du Pre, Marie; Di Niro, Roberto; Sollid, Ludvig Magne (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2015)
    Autoantibodies specific for the enzyme transglutaminase 2 (TG2) are a hallmark of the gluten-sensitive enteropathy celiac disease. Production of the Abs is strictly dependent on exposure to dietary gluten proteins, thus ...
  • The impact of irradiance on optimal and cellular nitrogen to phosphorus ratios in phytoplankton 
    Thrane, Jan-Erik; Hessen, Dag O.; Andersen, Tom (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
    Phytoplankton acclimates to irradiance by regulating the cellular content of light-harvesting complexes, which are nitrogen (N) rich and phosphorus (P) poor. Irradiance is thus hypothesised to influence the cellular N : P ...
  • Implications of poly(alkyl cyanoacrylate) nanoparticleinduced cellular stress responses with focus on autophagy 
    Sønstevold, Tonje (Doctoral thesis / Doktoravhandling, 2021)
    Nanoparticles are small particles in the nanometer size range, undetectable by the human eye. Nowadays nanoparticles are investigated as carriers of therapeutic drugs to increase treatment effect and minimize side effects ...
  • The importance of year-to-year variation in meteorological and runoff forcing for water quality of a temperate, dimictic lake 
    Romarheim, Aleksandra Tmic; Tominaga, Koji; Riise, Gunnhild; Andersen, Tom (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
    Natural stochasticity can pose challenges in managing the quality of the environment, or hinder understanding of the system structure. It is problematic because unfavourable stochastic events cancel management efforts and ...
  • The influence of dissolved organic carbon and ultraviolet radiation on the genomic integrity of Daphnia magna 
    Wolf, Raoul; Andersen, Tom; Hessen, Dag Olav; Hylland, Ketil (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
    1. Many northern freshwaters are currently experiencing a pronounced ‘browning’, that is an increase in terrestrially derived dissolved organic carbon (DOC). Chromophoric DOC offers protection against photodamage by absorbing ...
  • Insights into thermoadaptation and the evolution of mesophily from the bacterial phylum Thermotogae 
    Pollo, Stephen M.J.; Zhaxybayeva, Olga; Nesbø, Camilla Lothe (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2015)
    Thermophiles are extremophiles that grow optimally at temperatures >45 °C. To survive and maintain function of their biological molecules, they have a suite of characteristics not found in organisms that grow at moderate ...
  • Integrated chemical and biological assessment of contaminant impacts in selected European coastal and offshore marine areas 
    Hylland, Ketil; Robinson, Craig D.; Burgeot, Thierry; Martínez-Gómez, Concepción; Lang, Thomas; Svavarsson, Jörundur; Thain, John E.; Vethaak, A. Dick; Gubbins, Matthew J. (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
    This paper reports a full assessment of results from ICON, an international workshop on marine integrated contaminant monitoring, encompassing different matrices (sediment, fish, mussels, gastropods), areas (Iceland, North ...
  • Integration of DNA Methylation and Gene Expression in Lung Adenocarcinoma: Epigenetic Regulation, Patient Classification, and PrognosisRestricted Access 
    Brativnyk, Anastasia (Master thesis / Masteroppgave, 2022)
    Despite the increased molecular understanding of lung cancer, advances in therapy, and reduced smoking rates in developed countries, lung cancer remains the deadliest cancer type in the world today. Lung adenocarcinoma ...