Browsing Institutt for biovitenskap by Title
Now showing items 64-83 of 171
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)Background The expansion of offshore oil exploration increases the risk of marine species being exposed to oil pollution in currently pristine areas. The adverse effects of oil exposure through toxic ...
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Gene pleiotropy constrains gene expression changes in fish adapted to different thermal conditions (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)Understanding the factors that shape the evolution of gene expression is a central goal in biology, but the molecular mechanisms behind this remain controversial. A related major goal is ascertaining how such factors may ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)Divergent selection pressures induced by different environmental conditions typically lead to variation in life history, behavior, and morphology. When populations are locally adapted to their current environment, selection ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)Background Increased availability of genome assemblies for non-model organisms has resulted in invaluable biological and genomic insight into numerous vertebrates, including teleosts. Sequencing of the ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)Recent developments in the field of genomics have provided new and powerful insights into population structure and dynamics that are essential for the conservation of biological diversity. As a commercially highly valuable ...
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(Doctoral thesis / Doktoravhandling, 2018)The genomic landscape of a hybrid species is marked by alternating regions of parental inheritance and areas of genomic constraint which form reproductive barriers. A PhD candidate at the University of Oslo has explored ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)Computers are now essential in all branches of science, but most researchers are never taught the equivalent of basic lab skills for research computing. As a result, data can get lost, analyses can take much longer than ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)Background: Recent large-scale undertakings such as ENCODE and Roadmap Epigenomics have generated experimental data mapped to the human reference genome (as genomic tracks) representing a variety of functional elements ...
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(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)The neonatal crystallizable fragment receptor (FcRn) is responsible for maintaining the long half-life and high levels of the two most abundant circulating proteins, albumin and IgG. In the latter case, the protective ...
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(Journal article / Tidsskriftartikkel / SubmittedVersion, 2017)An international workshop on marine integrated contaminant monitoring (ICON) was organised to test a framework on integrated environmental assessment and simultaneously assess the status of selected European marine areas. ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)The interconnection of the endocytic and autophagosomal trafficking routes has been recognized more than two decades ago with both pathways using a set of identical effector proteins and sharing the same ultimate lysosomal ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)Albumin and IgG have remarkably long serum half-lives due to pH-dependent FcRn-mediated cellular recycling that rescues both ligands from intracellular degradation. Furthermore, increase in half-lives of IgG and albumin-based ...
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Igs as substrates for transglutaminase 2: Implications for autoantibody production in celiac disease (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2015)Autoantibodies specific for the enzyme transglutaminase 2 (TG2) are a hallmark of the gluten-sensitive enteropathy celiac disease. Production of the Abs is strictly dependent on exposure to dietary gluten proteins, thus ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)Phytoplankton acclimates to irradiance by regulating the cellular content of light-harvesting complexes, which are nitrogen (N) rich and phosphorus (P) poor. Irradiance is thus hypothesised to influence the cellular N : P ...
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(Doctoral thesis / Doktoravhandling, 2021)Nanoparticles are small particles in the nanometer size range, undetectable by the human eye. Nowadays nanoparticles are investigated as carriers of therapeutic drugs to increase treatment effect and minimize side effects ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)Natural stochasticity can pose challenges in managing the quality of the environment, or hinder understanding of the system structure. It is problematic because unfavourable stochastic events cancel management efforts and ...
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(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)1. Many northern freshwaters are currently experiencing a pronounced ‘browning’, that is an increase in terrestrially derived dissolved organic carbon (DOC). Chromophoric DOC offers protection against photodamage by absorbing ...
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Insights into thermoadaptation and the evolution of mesophily from the bacterial phylum Thermotogae (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2015)Thermophiles are extremophiles that grow optimally at temperatures >45 °C. To survive and maintain function of their biological molecules, they have a suite of characteristics not found in organisms that grow at moderate ...
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(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)This paper reports a full assessment of results from ICON, an international workshop on marine integrated contaminant monitoring, encompassing different matrices (sediment, fish, mussels, gastropods), areas (Iceland, North ...
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Integration of DNA Methylation and Gene Expression in Lung Adenocarcinoma: Epigenetic Regulation, Patient Classification, and PrognosisRestricted Access (Master thesis / Masteroppgave, 2022)Despite the increased molecular understanding of lung cancer, advances in therapy, and reduced smoking rates in developed countries, lung cancer remains the deadliest cancer type in the world today. Lung adenocarcinoma ...