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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)Strict control of tissue-specific gene expression plays a pivotal role during lineage commit- ment. The transcription factor c-Myb has an essential role in adult haematopoiesis and func- tions as an oncogene when rearranged ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)The transcription factor c-Myb is involved in early differentiation and proliferation of haematopoietic cells, where it operates as a regulator of self-renewal and multi-lineage differentiation. Deregulated c-Myb plays ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)Prostate cancer (PCa) is the most common non-cutaneous cancer in men. The androgen receptor (AR), a ligand-activated transcription factor, constitutes the main drug target for advanced cases of the disease. However, a ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)Hippocampal region CA2 has received increased attention due to its importance in social recognition memory. While its specific function remains to be identified, there are indications that CA2 plays a major role in a variety ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)The effect of poly(2-ethyl-butyl cyanoacrylate) nanoparticles containing the cytotoxic drug cabazitaxel was studied in three breast cancer cell lines and one basal-like patient-derived xenograft model grown in the mammary ...
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(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2021)Nanoparticles composed of poly(alkyl cyanoacrylate) (PACA) have shown great promise due to their biodegradability and high drug loading capacity. Development of optimal PACA nanocarriers requires detailed analysis of the ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)Despite numerous studies of selection on position and number of spectral vision bands, explanations to the function of narrow spectral bands are lacking. We investigate dragonflies (Odonata), which have the narrowest ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)The use of genetic markers under putative selection in population studies carries the potential for erroneous identification of populations and misassignment of individuals to population of origin. Selected markers are ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)Extracellular vesicles (EVs), are important for intercellular communication in both physiological and pathological processes. To explore the potential of cancer derived EVs as disease biomarkers for diagnosis, monitoring, ...
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CAR T cells as cancer immunotherapy to treat solid tumors - Construction of an immunocompetent mouse model to investigate a CAR targeting human STEAP1Begrenset tilgang (Master thesis / Masteroppgave, 2021)
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(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2020)With the increasing imperative for societies to act to curb climate change by increasing carbon stores and sinks, it has become critical to understand how organic carbon is produced, released, transformed, transported, and ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)The flourishing logistics in both developed and emerging economies leads to huge greenhouse gas (GHG) emissions; however, the emission fluxes are poorly constrained. Here, we constructed a spatial network of logistic GHG ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)Mass mortality events caused by pulse anthropogenic or environmental perturbations (e.g., extreme weather, toxic spills or epizootics) severely reduce the abundance of a population in a short time. The frequency and impact ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)Collapses and regime changes are pervasive in complex systems (such as marine ecosystems) governed by multiple stressors. The demise of Atlantic cod (Gadus morhua) stocks constitutes a text book example of the consequences ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)Studying the sublethal effects of catch-and-release (C&R) is challenging, as there are several potential sources of bias. For example, if behavioural alterations immediately after the release event are to be studied, ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)During a 2018 retrieval cruise for abandoned snow crab (Chionoecetes opilio) pots in the Barents Sea, approximately 8600 pots abandoned 1.5 years earlier were recovered. Forty-three percent of a subsample of 1000 pots ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)The SpyCatcher-SpyTag system was developed seven years ago as a method for protein ligation. It is based on a modified domain from a Streptococcus pyogenes surface protein (SpyCatcher), which recognizes a cognate 13-amino-acid ...
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(Chapter / Bokkapittel / PublishedVersion; Peer reviewed, 2020)The SpyCatcher-SpyTag system was developed seven years ago as a method for protein ligation. It is based on a modified domain from a Streptococcus pyogenes surface protein (SpyCatcher), which recognizes a cognate 13-amino-acid ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)Background Environmental DNA (eDNA) monitoring is growing increasingly popular in aquatic systems as a valuable complementary method to conventional monitoring. However, such tools have not yet been ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)Boreal lakes are the most abundant lakes on Earth. Changes in acid rain deposition, climate, and catchment land use have increased lateral fluxes of terrestrial dissolved organic matter (DOM), resulting in a widespread ...