Browsing Institutt for biovitenskap by Issue Date

Now showing items 21-40 of 2164

  • Differential Expression and Function of Stamp Family Proteins in Adipocyte Differentiation 
    Sikkeland, Jørgen; Saatcioglu, Fahri (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
    Six transmembrane protein of prostate (Stamp) proteins play an important role in prostate cancer cell growth. Recently, we found that Stamp2 has a critical role in the integration of inflammatory and metabolic signals in ...
  • Patterns of Saccharina latissima Recruitment 
    Andersen, Guri Sogn (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
    The lack of recovery in Norwegian populations of the kelp Saccharina latissima (Linnaeus) C. E. Lane, C. Mayes, Druehl & G. W. Saunders after a large-scale disturbance that occurred sometime between the late 1990s and early ...
  • Climate and demography dictate the strength of predator-prey overlap in a subarctic marine ecosystem 
    Hunsicker, Mary E.; Ciannelli, L; Bailey, Kevin M.; Zador, Stephani; Stige, Leif Christian (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
    There is growing evidence that climate and anthropogenic influences on marine ecosystems are largely manifested by changes in species spatial dynamics. However, less is known about how shifts in species distributions might ...
  • Comparisons of infant Escherichia coli isolates link genomic profiles with adaptation to the ecological niche 
    de Muinck, Eric J; Lagesen, Karin; Afset, Jan E; Didelot, Xavier; Rønningen, Kjersti S; Rudi, Knut; Stenseth, Nils C; Trosvik, Pål (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
    Background Despite being one of the most intensely studied model organisms, many questions still remain about the evolutionary biology and ecology of Escherichia coli. An important step toward achieving a ...
  • Omega-3 and omega-6 PUFAs induce the same GPR120-mediated signalling events, but with different kinetics and intensity in Caco-2 cells 
    Mobraten, Kaia; Haug, Trude M; Kleiveland, Charlotte R; Lea, Tor (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
    Background Omega-3 PUFAs are known to have anti-inflammatory properties, and different mechanisms are involved. GPR120 is a G-protein coupled receptor that has recently received attention because of its ...
  • IR/IGF1R signaling as potential target for treatment of high-grade osteosarcoma 
    Kuijjer, Marieke L; Peterse, Elisabeth F; van den Akker, Brendy E; Briaire-de Bruijn, Inge H; Serra, Massimo; Meza-Zepeda, Leonardo A; Myklebost, Ola; Hassan, A B; Hogendoorn, Pancras C; Cleton-Jansen, Anne-Marie (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
    Background High-grade osteosarcoma is an aggressive tumor most often developing in the long bones of adolescents, with a second peak in the 5th decade of life. Better knowledge on cellular signaling in this ...
  • The McNemar test for binary matched-pairs data: mid-p and asymptotic are better than exact conditional 
    Fagerland, Morten W; Lydersen, Stian; Laake, Petter (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
    Background Statistical methods that use the mid-p approach are useful tools to analyze categorical data, particularly for small and moderate sample sizes. Mid-p tests strike a balance between overly ...
  • Inferring the demographic history of European Ficedula flycatcher populations 
    Backström, Niclas; Sætre, Glenn-Peter; Ellegren, Hans (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
    Background Inference of population and species histories and population stratification using genetic data is important for discriminating between different speciation scenarios and for correct interpretation ...
  • Beak and skull shapes of human commensal and non-commensal house sparrows Passer domesticus 
    Riyahi, Sepand; Hammer, Øyvind; Arbabi, Tayebeh; Sánchez, Antonio; Roselaar, Cees S; Aliabadian, Mansour; Sætre, Glenn-Peter (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
    Background The granivorous house sparrow Passer domesticus is thought to have developed its commensal relationship with humans with the rise of agriculture in the Middle East some 10,000 years ago, and to ...
  • Home range plus: a space-time characterization of movement over real landscapes 
    Lyons, Andrew J; Turner, Wendy C; Getz, Wayne M (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
    Background Advances in GPS technology have created both opportunities in ecology as well as a need for analytical tools that can deal with the growing volume of data and ancillary variables associated with ...
  • Next generation sequencing shows high variation of the intestinal microbial species composition in Atlantic cod caught at a single location 
    Star, Bastiaan; Haverkamp, Thomas H; Jentoft, Sissel; Jakobsen, Kjetill S (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
    Background The observation that specific members of the microbial intestinal community can be shared among vertebrate hosts has promoted the concept of a core microbiota whose composition is determined by ...
  • Identification of pathways directly regulated by SHORT VEGETATIVE PHASE during vegetative and reproductive development in Arabidopsis 
    Gregis, Veronica; Andrés, Fernando; Sessa, Alice; Guerra, Rosalinda F; Simonini, Sara; Mateos, Julieta L; Torti, Stefano; Zambelli, Federico; Prazzoli, Gian M; Bjerkan, Katrine N; Grini, Paul E; Pavesi, Giulio; Colombo, Lucia; Coupland, George; Kater, Martin M (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
    Background MADS-domain transcription factors play important roles during plant development. The Arabidopsis MADS-box gene SHORT VEGETATIVE PHASE (SVP) is a key regulator of two developmental phases. It ...
  • A survey of protein interaction data and multigenic inherited disorders 
    Mora, Antonio; Michalickova, Katerina; Donaldson, Ian M (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
    Background Multigenic diseases are often associated with protein complexes or interactions involved in the same pathway. We wanted to estimate to what extent this is true given a consolidated protein ...
  • Single-chain Variable Fragment Albumin Fusions Bind the Neonatal Fc Receptor (FcRn) in a Species-dependent Manner: IMPLICATIONS FOR IN VIVO HALF-LIFE EVALUATION OF ALBUMIN FUSION THERAPEUTICS 
    Andersen, Jan Terje; Cameron, J; Plumridge, A; Sleep, D; Evans, L; Sandlie, Inger (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
    Albumin has a serum half-life of 3 weeks in humans. This has been utilized to extend the serum persistence of biopharmaceuticals that are fused to albumin. In light of the fact that the neonatal Fc receptor (FcRn) is a key ...
  • Chaperone-assisted thermostability engineering of a soluble T cell receptor using phage display 
    Gunnarsen, Kristin Støen; Kristinsson, Solveig Gunn; Justesen, Sune; Frigstad, Terje; Buus, Søren; Bogen, Bjarne; Sandlie, Inger; Løset, Geir Åge (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
    We here report a novel phage display selection strategy enabling fast and easy selection of thermostabilized proteins. The approach is illustrated with stabilization of an aggregation-prone soluble single chain T cell ...
  • Selection of Nanobodies that Target Human Neonatal Fc Receptor 
    Andersen, Jan Terje; Gonzalez-Pajuelo, Maria; Foss, Stian; Landsverk, Ole J. B.; Pinto, Debora; Szyroki, Alexander; de Haard, Hans J.; Saunders, Michael; Vanlandschoot, Peter; Sandlie, Inger (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
    FcRn is a key player in several immunological and non-immunological processes, as it mediates maternal-fetal transfer of IgG, regulates the serum persistence of IgG and albumin, and transports both ligands between different ...
  • Y Chromosome analysis of prehistoric human populations in the West Liao River Valley, Northeast China 
    Cui, Yinqiu; Li, Hongjie; Ning, Chao; Zhang, Ye; Chen, Lu; Zhao, Xin; Hagelberg, Erika; Zhou, Hui (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
    Background The West Liao River valley in Northeast China is an ecologically diverse region, populated in prehistory by human populations with a wide range of cultures and modes of subsistence. To help ...
  • Climate Change and Genetic Structure of Leading Edge and Rear End Populations in a Northwards Shifting Marine Fish Species, the Corkwing Wrasse (Symphodus melops) 
    Knutsen, Halvor; Jorde, Per Erik; Blanco Gonzalez, Enrique; Robalo, Joana I.; Albretsen, Jon; Almada, Vitor C. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
    One mechanism by which marine organisms may respond to climate shifts is range shifts. The corkwing wrasse (Symphodus melops) is a temperate fish species, inhabiting the coasts of Europe, that show strong indications of ...
  • Lévy meets Poisson: A Statistical Artifact May Lead to Erroneous Recategorization of Lévy Walk as Brownian Motion 
    Gautestad, Arild O. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
    The flow of GPS data on animal space is challenging old paradigms, such as the issue of the scale-free Lévy walk versus scale-specific Brownian motion. Since these movement classes often require different protocols with ...
  • Assessing the effects of climate on host-parasite interactions: a comparative study of European birds and their parasites 
    Møller, Anders Pape; Merino, Santiago; Soler, Juan José; Antonov, Anton; Badás, Elisa P.; Calero-Torralbo, Miguel A.; de Lope, Florentino; Eeva, Tapio; Figuerola, Jordi; Flensted-Jensen, Einar; Garamszegi, László Zsolt; González-Braojos, Sonia; Gwinner, Helga; Hanssen, Sveinn Are; Heylen, Dieter; Ilmone, Petteri; Klarborg, Kurt; Korpimäki, Erkki; Martínez, Javier; Martínez-de la Puente, Josue; Marzal, Alfonso; Matthysen, Erik; Matyjasiak, Piotr; Molina-Morales, Mercedes; Moreno, Juan; Mousseau, Timothy A.; Nielsen, Jan Tøttrup; Pap, Peter László; Rivero-de Aguilar, Juan; Shurulinkov, Peter; Slagsvold, Tore; Szép, Tibor; Szöllösi, Eszter; Török, Janos; Vaclav, Radovan; Valera, Fransisco; Ziane, Nadia (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
    Background: Climate change potentially has important effects on distribution, abundance, transmission and virulence of parasites in wild populations of animals. Methodology/Principal Finding: Here we analyzed paired ...