Browsing Institutt for biovitenskap by Title

Now showing items 1560-1579 of 2170

  • Productivity in the Barents Sea - Response to recent climate variability 
    Dalpadado, Padmini; Arrigo, Kevin R.; Hjøllo, Solfrid Sætre; Rey, Francisco; Ingvaldsen, Randi; Sperfeld, Erik; van Dijken, Gert L.; Stige, Leif Christian; Olsen, Are; Ottersen, Geir (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
    The temporal and spatial dynamics of primary and secondary biomass/production in the Barents Sea since the late 1990s are examined using remote sensing data, observations and a coupled physical-biological model. Field ...
  • Profiling of the small RNA populations in human testicular germ cell tumors shows global loss of piRNAs 
    Rounge, Trine Ballestad; Furu, Kari; Skotheim, Rolf Inge; Haugen, Trine B.; Grotmol, Tom; Enerly, Espen (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
    Background: Small non-coding RNAs play essential roles in gene regulation, however, the interplay between RNA groups, their expression levels and deregulations in tumorigenesis requires additional exploration. In particular, ...
  • Programmering i biovitenskapelige problemstillinger 
    Håland, Lars Erik Revheim (Master thesis / Masteroppgave, 2019)
    Programmering får en stadig sterkere rolle i de ulike realfagene. Dette ser vi gjennom fagfornyelsen i norsk grunn- og videregående skole, og på behovet i næringslivet. Universitetet i Oslo er blant de første i Norge til ...
  • Proposal to conserve the name Umbilicaria spodochroa (lichenized Ascomycota) with a conserved type and with that spelling 
    Hestmark, Geir (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
  • Prostate cancer and the unfolded protein response 
    Storm, Margrethe Larsdatter; Sheng, Xia; Arnoldussen, Yke Jildouw; Saatcioglu, Fahri (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
    The endoplasmic reticulum (ER) is an essential organelle that contributes to several key cellular functions, including lipogenesis, gluconeogenesis, calcium storage, and organelle biogenesis. The ER also serves as the major ...
  • Protease activated receptors (PAR)‐1 and ‐2 mediate cellular effects of factor VII activating protease (FSAP). 
    Byskov, Kristina; M. le Gall, Sylvain; Thiede, Bernd; Camerer, Eric; Kanse, Sandip (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Factor VII activating protease (FSAP) is a circulating serine protease implicated in thrombosis, atherosclerosis, stroke, and cancer. Using an overexpression strategy, we have systematically investigated the role of protease ...
  • Protection against Shiga Toxins 
    Kavaliauskiene, Simona; Anne Berit Dyve, Lingelem; Skotland, Tore; Sandvig, Kirsten (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    Shiga toxins consist of an A-moiety and five B-moieties able to bind the neutral glycosphingolipid globotriaosylceramide (Gb3) on the cell surface. To intoxicate cells efficiently, the toxin A-moiety has to be cleaved by ...
  • A protein kinase A-ezrin complex regulates connexin 43 gap junction communication in liver epithelial cells 
    Dukic, Aleksandra; Haugen, Linda Hofstad; Pidoux, Guillaume; Leithe, Edward; Bakke, Oddmund; Tasken, Kjetil (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
    Communication between adjacent cells can occur via gap junctions (GJ) composed of connexin (Cx) hexamers that allow passage of small molecules. One of the most widely and highly expressed Cxs in human tissues is Cx43, shown ...
  • Protein methylation in mitochondria 
    Malecki, Jedrzej Mieczyslaw; Davydova, Erna; Falnes, Pål (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    Many proteins are modified by posttranslational methylation, introduced by a number of methyltransferases (MTases). Protein methylation plays important roles in modulating protein function and thus in optimizing and ...
  • Protein Tyrosine Phosphatase Receptor Type G (PTPRG) controls Fibroblast Growth Factor Receptor (FGFR) 1 activity and influences sensitivity to FGFR kinase inhibitors 
    Kostas, Michal Janusz; Haugsten, Ellen Margrethe; Zhen, Yan; Sørensen, Vigdis; Szybowska, Patrycja Maria; Fiorito, Elisa; Lorenz, Susanne; Jones, Nina; De Souza, Gustavo Antonio; Wiedlocha, Antoni; Wesche, Jørgen (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    Recently, FGFR1 was found to be overexpressed in osteosarcoma and represents an important target for precision medicine. However, because targeted cancer therapy based on FGFR inhibitors has so far been less efficient than ...
  • Protein-coated nanostructured surfaces affect the adhesion of Escherichia coli 
    Kallas, Pawel; Valen, Håkon; Hulander, Mats; Gadegaard, Nikolaj; Stormonth-Darling, John; O'Reilly, Padraic; Thiede, Bernd; Andersson, Martin; Haugen, Håvard Jostein (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    Developing new implant surfaces with anti-adhesion bacterial properties used for medical devices remains a challenge. Here we describe a novel study investigating nanotopography influences on bacterial adhesion on surfaces ...
  • Proteogenomics analysis unveils a TFG-RET gene fusion and druggable targets in papillary thyroid carcinomas 
    Krishnan, Aswini; Berthelet, Jean; Renaud, Emilie; Rosigkeit, Sebastian; Distler, Ute; Stawiski, Eric; Wang, Jing; Modrusan, Zora; Fiedler, Marc; Bienz, Mariann; Tenzer, Stefan; Schad, Arno; Roth, Wilfried; Thiede, Bernd; Seshagiri, Somasekar; Musholt, Thomas J.; Rajalingam, Krishnaraj (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Papillary thyroid cancer (PTC) is the most common type of endocrine malignancy. By RNA-seq analysis, we identify a RET rearrangement in the tumour material of a patient who does not harbour any known RAS or BRAF mutations. ...
  • Proteoglycan synthesis in conserved oligomeric Golgi subunit deficient HEK293T cells is affected differently, depending on the lacking subunit 
    Adusumalli, Ravi; Åsheim, Hans-Christian; Lupashin, Vladimir; blackburn, jessica b; Prydz, Kristian (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    The Conserved Oligomeric Golgi (COG) complex is an eight subunit protein complex associated with Golgi membranes. Genetic defects affecting individual COG subunits cause congenital disorders of glycosylation (CDGs), due ...
  • Proteomic and histopathological characterisation of sicca subjects and primary Sjögren’s syndrome patients reveals promising tear, saliva and extracellular vesicle disease biomarkers 
    Aqrawi, Lara A; Galtung, Hilde K; Guerreiro, Eduarda M; Øvstebø, Reidun; Thiede, Bernd; Utheim, Tor P; Chen, Xiangjun; Utheim, Øygunn A; Palm, Øyvind; Skarstein, Kathrine; Jensen, Janicke L (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    Background Mononuclear cell infiltration of exocrine glands, production of Ro/SSA and La/SSB autoantibodies, along with oral and ocular dryness, are characteristic features of primary Sjögren’s syndrome ...
  • Proteomic Profiling of Saliva and Tears in Radiated Head and Neck Cancer Patients as Compared to Primary Sjögren’s Syndrome Patients 
    Hynne, Håvard; Aqrawi, Lara A.; Jensen, Janicke Liaaen; Thiede, Bernd; Palm, Øyvind; Amdal, Cecilie Delphin; Westgaard, Kristine Løken; Herlofson, Bente Brokstad; Utheim, Tor Paaske; Galtung, Hilde (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    Patients with head and neck cancer (HNC) and patients with primary Sjögren’s syndrome (pSS) may exhibit similar symptoms of dry mouth and dry eyes, as a result of radiotherapy (RT) or a consequence of disease progression. ...
  • Proteomics and lipidomics analyses reveal modulation of lipid metabolism by perfluoroalkyl substances in liver of Atlantic cod (Gadus morhua) 
    Dale, Karina; Yadetie, Fekadu; Müller, Mette Helen Bjørge; Pampanin, Daniela Maria; Gilabert, Alejandra; Zhang, Xiaokang; Tairova, Zhanna; Haarr, Ane; Lille-Langøy, Roger; Lyche, Jan Ludvig; Porte, Cinta; Karlsen, Odd Andre; Goksøyr, Anders (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    The aim of the present study was to investigate effects of defined mixtures of polycyclic aromatic hydrocarbons (PAHs) and perfluoroalkyl substances (PFASs), at low, environmentally relevant (1× = L), or high (20× = H) ...
  • Protist Diversity and Seasonal Dynamics in Skagerrak Plankton Communities as Revealed by Metabarcoding and Microscopy 
    Gran-Stadniczenko, Sandra; Egge, Elianne; Hostyeva, Vladyslava; Logares, Ramiro; Eikrem, Wenche; Edvardsen, Bente (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    Protist community composition and seasonal dynamics are of major importance for the production of higher trophic levels, such as zooplankton and fish. Our aim was to reveal how the protist community in the Skagerrak changes ...
  • Proton Compared to X-Irradiation Induces Different Protein Profiles in Oral Cancer Cells and Their Derived Extracellular Vesicles 
    Juvkam, Inga Solgård; Zlygosteva, Olga; Sitarz, Mateusz; Thiede, Bernd; Sørensen, Brita Singers; Malinen, Eirik; Edin, Nina Frederike Jeppesen; Søland, Tine Merete; Galtung, Hilde (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    Extracellular vesicles (EVs) are membrane-bound particles released from cells, and their cargo can alter the function of recipient cells. EVs from X-irradiated cells have been shown to play a likely role in non-targeted ...
  • Protozoan ALKBH8 Oxygenases Display both DNA Repair and tRNA Modification Activities 
    Zdzalik, Daria; Vågbø, Cathrine Broberg; Kirpekar, F; Davydova, Erna; Puścian, Alicja; Maciejewska, Agnieszka M.; Krokan, Hans Einar; Klungland, Arne; Tudek, Barbara; Van den Born, Erwin; Falnes, Pål (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
    The ALKBH family of Fe(II) and 2-oxoglutarate dependent oxygenases comprises enzymes that display sequence homology to AlkB from E. coli, a DNA repair enzyme that uses an oxidative mechanism to dealkylate methyl and etheno ...
  • PRP-19, a conserved pre-mRNA processing factor and E3 ubiquitin ligase, inhibits the nuclear accumulation of GLP-1/Notch intracellular domain. 
    Gutnik, Silvia; Thomas, Yann; Guo, Yanwu; Stoecklin, Janosch; Neagu, Anca; Pintard, Lionel; Merlet, Jorge; Ciosk, Rafal (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    The Notch signalling pathway is a conserved and widespread signalling paradigm, and its misregulation has been implicated in numerous disorders, including cancer. The output of Notch signalling depends on the nuclear ...