Browsing Institutt for biovitenskap by Title

Now showing items 1328-1347 of 2924

  • How do CD4+ T cells detect and eliminate tumor cells that either lack or express MHC class II molecules? 
    Haabeth, Ole Audun; Tveita, Anders; Fauskanger, Marte Hotvedt; Schjesvold, Fredrik Hellem; Lorvik, Kristina Berg; Hofgaard, Peter Olaf; Omholt, Hilde; Munthe, Ludvig Andre; Dembic, Zlatko; Corthay, Alexandre; Bogen, Bjarne (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
    CD4+ T cells contribute to tumor eradication, even in the absence of CD8+ T cells. Cytotoxic CD4+ T cells can directly kill MHC class II positive tumor cells. More surprisingly, CD4+ T cells can indirectly eliminate tumor ...
  • How does antibody-virus affinity affect TRIM21-mediated protection?Restricted Access 
    Lode, Heidrun Elisabeth (Master thesis / Masteroppgave, 2016)
  • How does the presence of neural probes affect extracellular potentials? 
    Buccino, Alessio Paolo; Kuchta, Miroslav; Jæger, Karoline Horgmo; Ness, Torbjørn V; Berthet, Pierre; Mardal, Kent-Andre; Cauwenberghs, Gert; Tveito, Aslak (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    Objective. Mechanistic modeling of neurons is an essential component of computational neuroscience that enables scientists to simulate, explain, and explore neural activity. The conventional approach to simulation of ...
  • How formal initiatives to improve teaching can lead to more significant informal conversations and increased sharing practice 
    Eidesen, Pernille Bronken; Førland, Oddfrid T. Kårstad; Håkansson, Lena; Christiansen, Hanne H.; Dahl, Tina; Strømseng, Elise (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    University teachers grow professionally from conversations about learning and teaching with colleagues. Significant informal conversations can be facilitated through formal activities initiated from the institutional side. ...
  • How general are generalist parasites? The small mammal part of the Lyme disease transmission cycle in two ecosystems in northern Europe 
    Mysterud, Atle; Stigum, Vetle Malmer; Linløkken, Harald Kolstad; Herland, Anders; Viljugrein, Hildegunn (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2019)
    The pathogens causing Lyme disease are all vectored by generalist tick species found on a wide range of vertebrates, but spatial and annual variation in host use has rarely been quantified. We here compare the load of ...
  • How genomics can help biodiversity conservation 
    Theissinger, Kathrin; Fernandes, Carlos; Formenti, Giulio; Bista, Iliana; Berg, Paul Ragnar; Bleidorn, Christoph; Bombarely, Aureliano; Crottini, Angelica; Gallo, Guido R.; Godoy, José A.; Jentoft, Sissel; Malukiewicz, Joanna; Mouton, Alice; Oomen, Rebekah Alice; Paez, Sadye; Palsbøll, Per J.; Pampoulie, Christophe; Ruiz-López, María J.; Secomandi, Simona; Svardal, Hannes; Theofanopoulou, Constantina; de Vries, Jan; Waldvogel, Ann-Marie; Zhang, Guojie; Jarvis, Erich D.; Bálint, Miklós; Ciofi, Claudio; Waterhouse, Robert M.; Mazzoni, Camila J.; Höglund, Jacob (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    The availability of public genomic resources can greatly assist biodiversity assessment, conservation, and restoration efforts by providing evidence for scientifically informed management decisions. Here we survey the main ...
  • How hydropower induced changes in temperature, quality and quantity of water influences structure and functioning of riverine biofilms 
    Pin, Lorenzo (Doctoral thesis / Doktoravhandling, 2022)
    River ecosystems are hot-spots of biodiversity, hosting many unique species and providing key ecosystem services. Nowadays these ecosystems are threatened by multiple stressors and human impact is the paramount reason. ...
  • How sampling-based overdispersion reveals India's tiger monitoring orthodoxy 
    Gopalaswamy, Arjun M.; Karanth, K. Ullas; Delampady, Mohan; Stenseth, Nils Christian (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    Agencies responsible for recovering populations of iconic mammals may exaggerate population trends without adequate scientific evidence. Recently, such populations were termed as “political populations” in the conservation ...
  • How the spatio-temporal overlap of cod, haddock, and capelin larvae affects their recruitment in the Norwegian–Barents Sea system 
    Ferreira, Sofia; Langangen, Øystein Ole Gahr; Yaragina, Nathalia A.; Prokopchuk, Irina P.; Durant, Joël (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2024)
    The Norwegian-Barents Sea (NBS) system is very productive; however, the extent to which this productivity varies remains uncertain for many species. Cod Gadus morhua , haddock Melanogrammus aeglefinus , and capelin Mallotus ...
  • How to avoid a local epidemic becoming a global pandemic 
    Stenseth, Nils Christian; Schlatte, Rudolf; Liu, Xiaoli; Pielke, Roger; Li, Ruiyun; Chen, Bin; Bjørnstad, Ottar Nordal; Kusnezov, Dimitri; Gao, George F.; Fraser, Christophe; Whittington, Jason D; Bai, Yuqi; Deng, Ke; Gong, Peng; Guan, Dabo; Xiao, Yixiong; Xu, Bing; Johnsen, Einar Broch (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    Here, we combine international air travel passenger data with a standard epidemiological model of the initial 3 mo of the COVID-19 pandemic (January through March 2020; toward the end of which the entire world locked down). ...
  • How to take autophagy and endocytosis up a notch 
    Barth, Julia Maria Isis; Köhler, Katja (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
    The interconnection of the endocytic and autophagosomal trafficking routes has been recognized more than two decades ago with both pathways using a set of identical effector proteins and sharing the same ultimate lysosomal ...
  • How will oil pollution and climate change affect an Arctic key zooplankton?Restricted Access 
    Gravelle, Amalie Marie Bårnås (Master thesis / Masteroppgave, 2023)
  • Hsp70 (HSPA1) lysine methylation status as a potential prognostic factor in metastatic high-grade serous carcinoma 
    Jakobsson, Magnus; Moen, Anders; Davidson, Ben; Falnes, Pål (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
    Cellular proteins are subject to frequent methylation on lysine residues, introduced by specific methyltransferases, and each lysine residue can receive up to three methyl groups. Histone methylations, which are key ...
  • Human activities increase vigilance, movement and home range size of the endangered mountain nyala (Tragelaphus buxtoni) at the cost of foraging and resting 
    Worku, Ejigu Alemayehu; Atickem, Anagaw Meshesha; Bro-Jørgensen, Jakob; Bekele, Afework; Evangelista, Paul; Stenseth, Nils Chr. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    Behavioral responses in wildlife due to human activities may often go unnoticed but have significant effects on population viability. This is a particular concern with endangered species characterized by small population ...
  • Human albumin-antigen fusions with improved FcRn binding and transport propertiesRestricted Access 
    Bern, Malin C. (Master thesis / Masteroppgave, 2013)
  • Human and mouse albumin bind their respective neonatal Fc receptors differently 
    Nilsen, Jeannette; Bern, Malin C.; Sand, Kine Marita Knudsen; Grevys, Algirdas; Dalhus, Bjørn; Sandlie, Inger; Andersen, Jan Terje (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
  • A human endothelial cell-based recycling assay for screening of FcRn targeted molecules 
    Grevys, Algirdas; Nilsen, Jeannette; Sand, Kine Marita Knudsen; Daba, Muluneh Bekele; Øynebråten, Inger; Bern, Malin C.; McAdam, Martin Berner; Foss, Stian; Schlothauer, Tilman; Michaelsen, Terje Einar; Christianson, Gregory J.; Roopenian, Derry C.; Blumberg, Richard S.; Sandlie, Inger; Andersen, Jan Terje (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    Albumin and IgG have remarkably long serum half-lives due to pH-dependent FcRn-mediated cellular recycling that rescues both ligands from intracellular degradation. Furthermore, increase in half-lives of IgG and albumin-based ...
  • Human IgG lacking effector functions demonstrate lower FcRn-binding and reduced transplacental transport 
    Stapleton, Nigel M.; Armstrong-Fisher, Sylvia S.; Andersen, Jan Terje; van der Schoot, C. Ellen; Porter, Charlene; Page, Kenneth R.; Falconer, Donald; de Haas, Masja; Williamson, Lorna M.; Clark, Michael R.; Vidarsson, Gestur; Armour, Kathryn L. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    We have previously generated human IgG1 antibodies that were engineered for reduced binding to the classical Fcγ receptors (FcγRI–III) and C1q, thereby eliminating their destructive effector functions (constant region ...
  • Human IgG subclasses in intracellular antiviral immunityRestricted Access 
    Jonsson, Alexandra (Master thesis / Masteroppgave, 2018)
  • Human METTL18 is a histidine-specific methyltransferase that targets RPL3 and affects ribosome biogenesis and function 
    Malecki, Jedrzej Mieczyslaw; O'Donohue, Marie-Francoise; Kim, Yeji; Jakobsson, Magnus; Gessa, Luca; Pinto, Rita; Wu, Jie; Davydova, Erna; Moen, Anders; Olsen, Jesper V.; Thiede, Bernd; Gleizes, Pierre-Emmanuel; Leidel, Sebastian A.; Falnes, Pål (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    Abstract Protein methylation occurs primarily on lysine and arginine, but also on some other residues, such as histidine. METTL18 is the last uncharacterized member of a group of human methyltransferases (MTases) ...