Browsing Høstingsarkiver by Author "O’Keefe, Ryan"

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  • A Mouse Model for the Rapid and Binomial Assessment of Putative WNT/β-Catenin Signalling Inhibitors 
    Tse, Janson; O’Keefe, Ryan; Rigopolous, Angela; Carli, Annalisa L. E.; Waaler, Jo; Krauss, Stefan Johannes Karl; Ernst, Matthias; Buchert, Michael (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    Specific signalling thresholds of the WNT/β-catenin pathway affect embryogenesis and tissue homeostasis in the adult, with mutations in this pathway frequently occurring in cancer. Excessive WNT/β-catenin activity inhibits ...