Browsing Høstingsarkiver by Author "Øvstebø, Reidun"
Now showing items 1-20 of 22
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Unhammer Njerve, Ida; Åkra, Sissel; Weiss, Thomas W.; Solheim, Svein; Øvstebø, Reidun; Aass, Hans Christian; Byrkjeland, Rune; Arnesen, Harald; Seljeflot, Ingebjørg (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
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Mazagão Guerreiro, Eduarda; Øvstebø, Reidun; Thiede, Bernd; Costea, Daniela Elena; Søland, Tine Merete; Galtung, Hilde (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)Extracellular vesicles (EVs), are important for intercellular communication in both physiological and pathological processes. To explore the potential of cancer derived EVs as disease biomarkers for diagnosis, monitoring, ...
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Øvstebø, Reidun; Pedersen, Geir Arild Feigum; Wilberg, Theresa; Røssberg, Jan Ivar; Dahl, Hanne-Sofie Johnsen; Kvarstein, Elfrida Hartveit (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)Objective This study examines how therapist emotional response/countertransference (CT) develops during treatment for patients with personality disorders (PDs) and how pre-treatment patient factors (severity of personality ...
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Aas, Vigdis; Øvstebø, Reidun; Brusletto, Berit; Aspelin, Trude; Siebke, Anne-Marie; Qureshi, Saba; Eid, Desima Shitandi Otundo; Olstad, Ole Kristoffer; Nyman, Tuula Anneli; Foss Haug, Kari Bente (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)Lifestyle disorders like obesity, type 2 diabetes (T2D), and cardiovascular diseases can be prevented and treated by regular physical activity. During exercise, skeletal muscles release signaling factors that communicate ...
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Hellum, Marit Synnøve; Franco-Lie, I; Øvstebø, Reidun; Hauge, Truls; Henriksson, Carola (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)Circulating microvesicles (MVs) are suggested to be important contributors to cancer-associated thrombosis due to the presence of surface-bound procoagulant molecules like tissue factor (TF) and phosphatidylserine (PS). ...
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Guerreiro, Eduarda; Vestad, Beate; Steffensen, Lilly Alice; Aass, Hans Christian Dalsbotten; Saeed, Muhammad; Øvstebø, Reidun; Costea, Daniela Elena; Galtung, Hilde; Søland, Tine Merete (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)Extracellular vesicles (EVs) are a heterogeneous population of biological particles released by cells. They represent an attractive source of potential biomarkers for early detection of diseases such as cancer. However, ...
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Brusletto, Berit Sletbakk; Løberg, Else Marit; Hellerud, Bernt C; Goverud, Ingeborg Løstegaard; Berg, Jens Petter; Olstad, Ole Kristoffer; Gopinathan, Unni; Brandtzæg, Petter; Øvstebø, Reidun (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)Background: Patients developing meningococcal septic shock reveal levels of Neisseria meningitidis (106-108/mL) and endotoxin (101-103 EU/mL) in the circulation and organs, leading to acute cardiovascular, pulmonary and ...
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Piehler, Armin P; Grimholt, Runa M; Øvstebø, Reidun; Berg, Jens P (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2010)Background Gene expression in lipopolysaccharide (LPS)-stimulated monocytes is mainly studied by quantitative real-time reverse transcription PCR (RT-qPCR) using GAPDH (glyceraldehyde 3-phosphate dehydrogenase) ...
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Aqrawi, Lara A; Galtung, Hilde K; Vestad, Beate; Øvstebø, Reidun; Thiede, Bernd; Rusthen, Shermin; Young, Alix; Guerreiro, Eduarda M; Utheim, Tor P; Chen, Xiangjun; Utheim, Øygunn A; Palm, Øyvind; Jensen, Janicke L (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)Background There is a long-lasting need for non-invasive, more accurate diagnostic techniques when evaluating primary Sjögren’s syndrome (pSS) patients. Incorporation of additional diagnostics involving ...
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Haugsten, Helene Rygvold; Kristoffersen, Anne Karin; Haug, Trude Marie; Søland, Tine Merete; Øvstebø, Reidun; Aass, Hans Christian; Enersen, Morten; Galtung, Hilde (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)Periodontitis is an inflammatory condition caused by bacteria and represents a serious health problem worldwide as the inflammation damages the supporting tissues of the teeth and may predispose to systemic diseases. ...
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Gopinathan, Unni; Redalen, Kathrine; Siebke, Anne-Marie; Kierulf, Peter; Brandtzæg, Petter Bae; Ree, Anne Hansen; Berg, Jens Petter; Øvstebø, Reidun (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)N. meningitidis induces extensive gene expression changes in human monocytes, suggesting that complex networks of signaling pathways are activated during meningococcal sepsis. These effects are modulated by the anti-inflammatory ...
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Mihret, Wude; Brusletto, Berit Sletbakk; Øvstebø, Reidun; Siebke, Anne-Marie; Norheim, Gunnstein; Merid, Yared; Kassu, Afework; Abebe, Workeabeba; Ayele, Samuel; Silamsaw, Mezgebu; Yamuah, Lawrence; Aseffa, Abraham; Petros, Beyene; Caugant, Dominique A; Brandtzaeg, Petter (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)Neisseria meningitidis infections in sub-Saharan Africa usually present with distinct symptoms of meningitis but very rarely as fulminant septicemia when reaching hospitals. In Europe, development of persistent meningococcal ...
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Brusletto, Berit; Hellerud, Bernt C; Øvstebø, Reidun; Brandtzæg, Petter (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)Background Neisseria meningitidis (Nm) is the cause of epidemic meningitis and fulminant meningococcal septicemia. The clinical presentations and outcome of meningococcal septic shock is closely related to the circulating ...
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Non-Coding RNA in Salivary Extracellular Vesicles: A New Frontier in Sjögren's Syndrome Diagnostics? Cross, Tanya; Haug, Kari Bente Foss; Brusletto, Berit; Ommundsen, Stine Kamilla; Trøseid, Anne-Marie Siebke; Aspelin, Trude; Olstad, Ole Kristoffer; Aass, Hans Christian; Galtung, Hilde; Utheim, Tor Paaske; Jensen, Janicke Liaaen; Øvstebø, Reidun (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)Sjögren’s syndrome is an autoimmune rheumatic disease characterized by inflammation of the salivary and lacrimal glands, often manifesting as dry mouth and dry eyes. To simplify diagnostics of primary Sjögren’s syndrome ...
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Vestad, Beate; Nyman, Tuula A.; Hove-Skovsgaard, Malene; Stensland, Maria; Hoel, Hedda Benedicte; Siebke, Anne-Marie; Aspelin, Trude; Aass, Hans Christian Dalsbotten; Puhka, Maija; Hov, Johannes R.; Nielsen, Susanne Dam; Øvstebø, Reidun; Trøseid, Marius (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)Abstract HIV and type 2 diabetes (T2D) are both associated with gut microbiota alterations, low-grade endotoxemia and increased cardiovascular risk. We investigated the potential role of plasma extracellular vesicles (EVs) ...
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Aqrawi, Lara A; Galtung, Hilde K; Guerreiro, Eduarda M; Øvstebø, Reidun; Thiede, Bernd; Utheim, Tor P; Chen, Xiangjun; Utheim, Øygunn A; Palm, Øyvind; Skarstein, Kathrine; Jensen, Janicke L (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)Background Mononuclear cell infiltration of exocrine glands, production of Ro/SSA and La/SSB autoantibodies, along with oral and ocular dryness, are characteristic features of primary Sjögren’s syndrome ...
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Vestad, Beate; Llorente, Alicia; Neurauter, Axl; Phuyal, Santosh; Kierulf, Bente; Kierulf, Peter; Skotland, Tore; Sandvig, Kirsten; Foss, Kari Bente; Øvstebø, Reidun (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)Current methods for characterisation of extracellular vesicles (EVs) need further standardisation in order to obtain an acceptable level of data comparability. Size and concentration of EVs can be determined by nanoparticle ...
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Brusletto, Berit S; Hellerud, Bernt C; Løberg, Else M; Goverud, Ingeborg L; Vege, Åshild; Berg, Jens P; Brandtzaeg, Petter; Øvstebø, Reidun (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)Background The pathophysiology and outcome of meningococcal septic shock is closely associated with the plasma level of N. meningitidis lipopolysaccharides (LPS, endotoxin) and the circulating level of ...
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Brusletto, Berit Sletbakk; Hellerud, Bernt C; Olstad, Ole Kristoffer; Øvstebø, Reidun; Brandtzæg, Petter (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)Background: Fulminant meningococcal sepsis with shock and multiple organ failure is associated with a massive systemic inflammatory response involving solid organs. We have previously established a porcine model of the ...
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Gopinathan, Unni; Øvstebø, Reidun; Brusletto, Berit S; Olstad, Ole K; Kierulf, Peter; Brandtzaeg, Petter; Berg, Jens P (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)Background Biological interpretation of DNA microarray data may differ depending on underlying assumptions and statistical tests of bioinformatics tools used. We used Gene Set Enrichment Analysis (GSEA) and ...