Browsing Høstingsarkiver by Author "Åsberg, Anders"
Now showing items 1-20 of 81
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Tsarpali, Vasiliki; Midtvedt, Karsten; Lønning, Kjersti; Bernklev, Tomm; Åsberg, Anders; Fawad, Haris; Lippe, Nanna von der; Reisæter, Anna Varberg; Røysland, Kjetil; Heldal, Kristian (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)Kidney transplantation (KT) is considered the best treatment for end-stage kidney disease (ESKD). In the increasing elderly ESKD population, KT should be reserved for carefully selected candidates who are expected to ...
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Hovd, Markus Herberg; Robertsen, Ida; Woillard, Jean-Baptiste; Åsberg, Anders (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)In combination with Bayesian estimates based on a population pharmacokinetic model, limited sampling strategies (LSS) may reduce the number of samples required for individual pharmacokinetic parameter estimations. Such ...
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Jager, Kitty J; Åsberg, Anders; Collart, Frédéric; Couchoud, Cécile; Evans, Marie; Finne, Patrik; Peride, Ilena; Rychlik, Ivan; Massy, Ziad A. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)BACKGROUND Traditionally, renal registries collect and report population-based epidemiological data on patients with kidney failure who are treated by kidney replacement therapy (KRT), i.e. dialysis or transplantation. ...
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Stillemans, Gabriel; Paquot, Adrien; Muccioli, Giulio G.; Hoste, Emilia; Panin, Nadtha; Åsberg, Anders; Balligand, Jean-Luc; Haufroid, Vincent; Elens, Laure (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)The purpose of this study was to investigate the potential clinical relevance of estimating the apparent clearance (CL/F) of atorvastatin through population pharmacokinetic (PopPK) modeling with samples collected in a ...
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Onsøien, Mari Olsen; Midtvedt, Karsten; Reisæter, Anna Varberg; Aasarød, Knut; Waldum-Grevbo, Bård; Vikse, Bjørn Egil; Eriksen, Bjørn Odvar; Åsberg, Anders (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)Background. Hypertension in kidney transplant (KTx) recipients is common, affecting both patient and graft survival. Annual data from the Norwegian Renal Registry reveal that <50% of adult (>18 y) KTx recipients reach ...
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Blom, Kjersti Benedicte; Bergo, Kaja Knudsen; Espe, Emil Knut Stenersen; Rosseland, Vigdis; Grøtta, Ole Jørgen; Mjøen, Geir; Åsberg, Anders; Bergan, Stein; Sanner, Helga; Bergersen, Tone Kristin; Bjørnerheim, Reidar; Skauby, Morten Heier; Seljeflot, Ingebjørg; Waldum-Grevbo, Bård; Dahle, Dag Olav; Sjaastad, Ivar; Birkeland, Jon Arne (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2020)Purpose: Until recently, it has been believed that donating a kidney not represents any risk for development of cardiovascular disease. However, a recent Norwegian epidemiological study suggests that kidney donors have an ...
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Vethe, Nils Tore; Åsberg, Anders; Andersen, Anders Mikal; Skauby, Ragnhild Kristine Heier; Bergan, Stein; Midtvedt, Karsten (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)Aims Finger‐prick sampling has emerged as an attractive tool for therapeutic drug monitoring and associated diagnostics. We aimed to validate the clinical performance of using two volumetric devices (Capitainer® qDBS and ...
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Krogstad, Veronica; Peric, Alexandra; Robertsen, Ida; Kringen, Marianne K.; Vistnes, Maria; Hjelmesæth, Jøran; Sandbu, Rune; Johnson, Line Kristin; Angeles, Philip Carlo Soriano; Jansson-Löfmark, Rasmus; Karlsson, Cecilia; Andersson, Shalini; Åsberg, Anders; Andersson, Tommy B.; Christensen, Hege Staaland (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)Obesity is associated with comorbidities of which pharmacological treatment is needed. Physiological changes associated with obesity may influence the pharmacokinetics of drugs, but the effect of body weight on drug ...
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Kvitne, Kine Eide; Hole, Kristine; Krogstad, Veronica; Wollmann, Birgit Malene Tovik; Wegler, Christine; Johnson, Line Kristin; Hertel, Jens Kristoffer; Artursson, Per; Karlsson, Cecilia; Andersson, Shalini; Andersson, Tommy B.; Sandbu, Rune; Hjelmesæth, Jøran Sture; Skovlund, Eva; Christensen, Hege; Jansson-Löfmark, Rasmus; Åsberg, Anders; Molden, Espen; Robertsen, Ida (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)Abstract Purpose Variability in cytochrome P450 3A4 (CYP3A4) metabolism is mainly caused by non-genetic factors, hence providing a need for accurate phenotype biomarkers. Although 4β-hydroxycholesterol ...
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Størset, Elisabet; Hole, Kristine; Midtvedt, Karsten; Bergan, Stein; Molden, Espen; Åsberg, Anders (Journal article / Tidsskriftartikkel / SubmittedVersion, 2017)Aims: Tacrolimus is a cornerstone in modern immunosuppressive therapy after kidney transplantation. Tacrolimus dosing is challenged by considerable pharmacokinetic variability, both between patients and over time after ...
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Vinknes, Kathrine Jørgensen; Olsen, Thomas; Zare, Hasse Khiabani; Bastani, Nasser Ezzatkhah; Stolt, Emma Theresia Kjelland; Dahl, Anja Falkenhaug; Cox, Roger D.; Refsum, Helga; Åsberg, Anders; Elshorbagy, Amany (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)Abstract Aim To investigate whether mesna—sodium‐2‐mercaptoethane sulfonate) can reduce diet‐induced fat gain in mice, and to assess the safety of single ascending mesna doses in humans to find the dose associated with ...
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Blom, Kjersti Benedicte; Kro, Grete Anette Birkeland; Midtvedt, Karsten; Jenssen, Trond; Reisæter, Anna Varberg; Rollag, Halvor; Hartmann, Anders; Sagedal, Solbjørg; Sjaastad, Ivar; Tylden, Garth Daryl; Njølstad, Gro; Nilsen, Einar; Christensen, Andreas; Åsberg, Anders; Birkeland, Jon Arne (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)Background. Following kidney transplantation (KT), cytomegalovirus (CMV) infection remains an important challenge. Both prophylactic and preemptive antiviral protocols are used for CMV high-risk kidney recipients (donor ...
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Helanterä, Ilkka; Snyder, Jon; Åsberg, Anders; Cruzado, Josep María; Bell, Samira; Legendre, Christophe; Tedesco-Silva, Helio; Barcelos, Giovanna Tedesco; Geissbühler, Yvonne; Prieto, Luisa; Christian, Jennifer B.; Scalfaro, Erik; Dreyer, Nancy A. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)While great progress has been made in transplantation medicine, long-term graft failure and serious side effects still pose a challenge in kidney transplantation. Effective and safe long-term treatments are needed. Therefore, ...
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Kvitne, Kine Eide; Hovd, Markus; Johnsen, Line Kristin; Wegler, Christine; Karlsson, Cecilia; Artursson, Per; Andersson, Shalini; Sandbu, Rune; Hjelmesæth, Jøran Sture; Skovlund, Eva; Jansson-Löfmark, Rasmus; Christensen, Hege; Åsberg, Anders; Robertsen, Ida (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)Background and Objective Several drugs on the market are substrates for P-glycoprotein (P-gp), an efflux transporter highly expressed in barrier tissues such as the intestine. Body weight, weight loss, and a Roux-en-Y ...
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Drug disposition protein quantification in matched human jejunum and liver from donors with obesity Wegler, Christine; Wisniewski, Jacek R.; Robertsen, Ida; Christensen, Hege; Hertel, Jens Kristoffer; Hjelmesæth, Jøran Sture; Jansson-Löfmark, Rasmus; Åsberg, Anders; Andersson, Tommy B; Artursson, Per (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)Mathematical models, such as physiologically based pharmacokinetic (PBPK) models, are used to predict e.g., drug disposition and toxicity. However, populations differ in the abundance of proteins involved in these processes. ...
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Strøm Halden, Thea Anine; Kvitne, Kine Eide; Midtvedt, Karsten; Rajakumar, Laavanyaah; Robertsen, Ida; Brox, Jan; Bollerslev, Jens; Hartmann, Anders; Åsberg, Anders; Jenssen, Trond Geir (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2019)OBJECTIVE Sodium–glucose cotransporter 2 (SGLT2) inhibitors have lately become the recommended treatment in patients with type 2 diabetes and high cardiovascular risk. Patients with posttransplant diabetes mellitus (PTDM) ...
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Witczak, Bartlomiej J; Pischke, Søren E.; Reisæter, Anna V.; Midtvedt, Karsten; Ludviksen, Judith K; Heldal, Kristian; Jenssen, Trond; Hartmann, Anders; Åsberg, Anders; Mollnes, Tom E. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)Background The major reason for graft loss is chronic tissue damage, as interstitial fibrosis and tubular atrophy (IF/TA), where complement activation may serve as a mediator. The association of complement activation in a ...
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Robertsen, Ida; Falck, Pål; Andreassen, Arne K; Næss, Nina K; Lunder, Niclas; Christensen, Hege; Gullestad, Lars; Åsberg, Anders (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)Background In the early phases following heart transplantation a main challenge is to reduce the impact of acute rejections. Previous studies indicate that intracellular ciclosporin A (CsA) concentration ...
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Langberg, Nina Elisabeth Borthen; Jenssen, Trond Geir; Haugen, Anders; Mjøen, Geir; Birkeland, Kåre Inge; Åsberg, Anders; Hartmann, Anders; Dahle, Dag Olav (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)Background. Endothelial dysfunction is an early and potentially reversible stage in the atherosclerotic process. We assessed endothelial dysfunction noninvasively in kidney transplant recipients (KTRs) and evaluated ...
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Heldal, Kristian; Midtvedt, Karsten; Hartmann, Anders; Reisæter, Anna Varberg; Heldal, Torbjørn Fossum; Bergan, Stein; Salvador, Cathrin Lytomt; Åsberg, Anders (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2018)Several equations have been developed for estimated glomerular filtration rate (eGFR) in patients with chronic kidney disease (CKD), but none were developed based on data from elderly kidney transplant recipients (KTR). ...