Browsing Høstingsarkiver by Title
Now showing items 25280-25299 of 34663
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)Supersymmetric models with R-parity violation (RPV) have become more popular following the lack of any excess of missing energy events at the 8 TeV LHC. To identify such models, the suggested searches generally rely on the ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)Background Machine learning involves strategies and algorithms that may assist bioinformatics analyses in terms of data mining and knowledge discovery. In several applications, viz. in Life Sciences, it is ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)Internal therapy with α‐emitters should be well suited for micrometastatic disease. Radium‐224 emits multiple α‐particles through its decay and has a convenient 3.6 days of half‐life. Despite its attractive properties, the ...
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(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2018)The intracellular movement and positioning of organelles and vesicles is mediated by the cytoskeleton and molecular motors. Small GTPases like Rab and Arf proteins are main regulators of intracellular transport by connecting ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)Rab proteins compose the largest family of small GTPases and control the different steps of intracellular membrane traffic. More recently, they have been shown to also regulate cell signaling, division, survival, and ...
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Rab18 regulates focal adhesion dynamics by interacting with kinectin-1 at the endoplasmic reticulum (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)The members of the Rab family of small GTPases are molecular switches that regulate distinct steps in different membrane traffic pathways. In addition to this canonical function, Rabs can play a role in other processes, ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)Rab proteins are well known regulators of intracellular trafficking; however, more and more studies point to their function also in other cellular processes, including cell migration. In this work, we have performed an ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)Abstract HER2 is a predictive biomarker for HER2-targeted therapeutics. For antibody–drug conjugates (ADCs; e.g., trastuzumab emtansine (T-DM1)), HER2 is utilized as a transport gate for cytotoxic agents into the cell. ADC ...
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(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2019)Rab proteins are master regulators of intracellular membrane trafficking, but they also contribute to cell division, signaling, polarization, and migration. The majority of the works describing the mechanisms used by Rab ...
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(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)Rab7a, a small GTPase of the Rab family, is localized to late endosomes and controls late endocytic trafficking. The discovery of several Rab7a interacting proteins revealed that Rab7a function is closely connected to ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)Autophagy (macroautophagy) is a highly conserved eukaryotic degradation pathway in which cytosolic components and organelles are sequestered by specialized autophagic membranes and degraded through the lysosomal system. ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)Lysosomal signaling facilitates the migration of immune cells by releasing calcium to activate the actin-based motor myosin II at the cell rear. However, how the actomyosin cytoskeleton physically associates to lysosomes ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)Policy innovation in unitary states relies heavily on the proclivity of local governments to identify and respond to emerging policy challenges. The article contributes by applying a framework for policy innovation normally ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)Globally, rabies remains a serious threat to public health. In particular, large number of cases continue to be detected in Africa and Asia. China has experienced three major outbreaks with the current epizootic starting ...
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Race duration and blood pressure are major predictors of exercise-induced cardiac troponin elevation (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2019)Background The underlying mechanisms of the exercise-induced increase in cardiac troponins (cTn) are poorly understood. The aim of this study was to identify independent determinants of exercise-induced cTn increase in a ...
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(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2021)Historically, laws and policies to criminalize drug use or possession were rooted in explicit racism, and they continue to wreak havoc on certain racialized communities. We are a group of bioethicists, drug experts, legal ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)Abstract Attenuation of radar waves in the subsurface can be quantified with a constant‐Q approximation through time‐frequency analysis. We implement the centroid frequency‐shift method and study Radar Imager for Mars' ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)Abstract The Radar Imager for Mars’ Subsurface Experiment (RIMFAX) is a Ground Penetrating Radar on the Mars 2020 mission’s Perseverance rover, which is planned to land near a deltaic landform in Jezero crater. RIMFAX ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)The High Luminosity LHC (HL-LHC) upgrade requires the planned Inner Tracker (ITk) of the ATLAS detector to tolerate extremely high radiation doses. Specifically, the innermost parts of the pixel system will have to withstand ...