Browsing Høstingsarkiver by Title

Now showing items 4049-4068 of 34663

  • C-type lectin receptors Mcl and Mincle control development of multiple sclerosis-like neuroinflammation 
    N'Diaye, Marie; Brauner, Susanna; Flytzani, Sevasti; Kular, Lara; Warnecke, Andreas; Adzemovic, Milena Z.; Piket, Eliane; Min, Jin-Hong; Edwards, Will; Mela, Filia; Choi, Hoi Ying; Magg, Vera; James, Tojo; Lindén, Magdalena; Reichardt, Holger M.; Daws, Michael Rory; Van Horssen, Jack; Kockum, Ingrid; Harris, Robert A.; Olsson, Tomas; Guerreiro-Cacais, Andre O.; Jagodic, Maja (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Pattern recognition receptors (PRRs) are crucial for responses to infections and tissue damage; however, their role in autoimmunity is less clear. Herein we demonstrate that 2 C-type lectin receptors (CLRs) Mcl and Mincle ...
  • C-type lectin-like CD161 is not a co-signalling receptor in gluten-reactive CD4 + T cells 
    Wyrozemski, Lukasz Adam; Sollid, Ludvig Magne; Qiao, Shuo Wang (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2020)
    C‐type lectin‐like CD161, a class II transmembrane protein, is a surface receptor expressed by NK cells and T cells. In coeliac disease, CD161 was expressed more frequently on gluten‐reactive CD4 + T cells compared to other ...
  • C-X-C ligand 16 is an independent predictor of cardiovascular death and morbidity in acute coronary syndromes 
    Andersen, Thomas; Ueland, Thor; Ghukasyan Lakic, Tatevik; Åkerblom, Axel; Bertilsson, Maria; Aukrust, Pål; Michelsen, Annika E; James, Stefan K.; Becker, Richard C.; Storey, Robert F.; Wallentin, Lars; Siegbahn, Agneta; Kontny, Frederic (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2019)
    Objective: The chemokine CXCL16 (C-X-C motif ligand 16) is a scavenger receptor for OxLDL (oxidized low-density lipoproteins) and involved in inflammation at sites of atherosclerosis. This study aimed to investigate the ...
  • C. elegans as an Animal Model to Study the Intersection of DNA Repair, Aging and Neurodegeneration 
    Naranjo-Galindo, Francisco José; Ai, Ruixue; Fang, Evandro Fei; Nilsen, Hilde Loge; SenGupta, Tanima (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    Since its introduction as a genetic model organism, Caenorhabditis elegans has yielded insights into the causes of aging. In addition, it has provided a molecular understanding of mechanisms of neurodegeneration, one of ...
  • C/2014 UN271 (Bernardinelli-Bernstein): The Nearly Spherical Cow of Comets 
    Bernardinelli, Pedro H.; Bernstein, Gary M.; Montet, Benjamin T.; Weryk, Robert; Wainscoat, Richard; Aguena, Michel; Allam, Sahar; Andrade-Oliveira, F.; Annis, J.; Avila, S.; Bertin, E.; Brooks, D.; Burke, David L.; Carnero Rosell, Aurelio; Carrasco Kind, Matias; Carretero, Jorge; Cawthon, R.; Conselice, Christopher; Costanzi, M.; da Costa, L. N.; Pereira, Maria Elidaiana da Silva; De Vicente, J.; Diehl, Herman T.; Everett, S.; Ferrero, Ismael; Flaugher, B.; Frieman, J.; García-Bellido, Juan; Gaztañaga, Enrique; Gerdes, David W.; Gruen, Daniel; Gruendl, Robert A.; Gschwend, J.; Gutierrez, G.; Hinton, Samuel R.; Hollowood, Devon L.; Honscheid, Klaus; James, D. J.; Kuehn, Kyler; Kuropatkin, Nikolay; Lahav, Ofer; Maia, Marcio A. G.; Marshall, Jennifer L.; Menanteau, Felipe; Miquel, Ramon; Morgan, Robert; Ogando, Ricardo L. C.; Paz-Chinchón, Francisco; Pieres, Adriano; Plazas Malagón, A. A.; Rodriguez-Monroy, M.; Romer, A. K.; Roodman, A.; Sanchez, E.; Schubnell, M.; Serrano, S.; Sevilla-Noarbe, Ignacio; Smith, M.; Soares-Santos, Marcelle; Suchyta, E.; Swanson, Molly E. C.; Tarlé, Gregory; To, Chun-Hao; Troxel, M. A.; Varga, T. N.; Walker, A. R.; Zhang, Y. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
  • C57BL/6J mice as a polygenic developmental model of diet-induced obesity 
    Chu, Dinh Toi; Malinowska, Elzbieta; Jura, Magdalena; Kozak, Leslie P (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    Susceptibility to obesity changes during the course of life. We utilized theC57BL/6J (B6) and 129S mouse as a genetic model for variation in diet-induced obesity to define the adiposity phenotypes from birth to maturity ...
  • C77G in PTPRC (CD45) is no risk allele for ovarian cancer, but associated with less aggressive disease 
    Landskron, Johannes; Kraggerud, Sigrid M.; Wik, Elisabeth; Dørum, Anne; Bjørnslett, Merete Pauline; Melum, Espen; Helland, Øystein; Bjørge, Line; Lothe, Ragnhild A; Salvesen, Helga; Tasken, Kjetil (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    The pan lymphocyte marker CD45 exists in various isoforms arising from alternative splicing of the exons 4, 5 and 6. While naïve T cells express CD45RA translated from an mRNA containing exon 4, exons 4–6 are spliced out ...
  • C9orf72, age at onset, and ancestry help discriminate behavioral from language variants in FTLD cohorts 
    Costa, Beatrice; Manzoni, Claudia; Bernal-Quiros, Manual; Kia, Demis A.; Aguilar, Miquel; Alvarez, Ignacio; Alvarez, Victoria; Andreassen, Ole Andreas; Anfossi, Maria; Bagnoli, Silvia; Benussi, Luisa; Bernardi, Livia; Binetti, Giuliano; Blackburn, Daniel; Boada, Mercè; Borroni, Barbara; Bowns, Lucy; Bråthen, Geir; Bruni, Amalia C; Chiang, Huei-Hsin; Clarimon, Jordi; Colville, Shuna; Conidi, Maria E; Cope, Tom E; Cruchaga, Carlos; Cupidi, Chiara; Di Battista, Maria Elena; Diehl-Schmid, Janine; Diez-Fairen, Monica; Dols-Icardo, Oriol; Durante, Elisabetta; Flisar, Dusan; Frangipane, Francesca; Galimberti, Daniela; Gallo, Maura; Gallucci, Mauricio; Ghidoni, Roberta; Graff, Caroline; Grafman, Jordan H; Grossman, Murray; Hardy, John; Hernández, Isabel; Holloway, Guy J T; Huey, Edward D; Illán-Gala, Ignacio; Karydas, Anna; Khoshnood, Behzad; Kramberger, Milica G.; Kristiansen, Mark K; Sando, Sigrid Botne (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Objective: We sought to characterize C9orf72 expansions in relation to genetic ancestry and age at onset (AAO) and to use these measures to discriminate the behavioral from the language variant syndrome in a large pan-European ...
  • C@PA: Computer-Aided Pattern Analysis to Predict Multitarget ABC Transporter Inhibitors 
    Namasivayam, Vigneshwaran; Silbermann, Katja; Wiese, Michael; Pahnke, Jens; Stefan, Sven Marcel (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    Based on literature reports of the last two decades, a computer-aided pattern analysis (C@PA) was implemented for the discovery of novel multitarget ABCB1 (P-gp), ABCC1 (MRP1), and ABCG2 (BCRP) inhibitors. C@PA included ...
  • CA2 beyond social memory: Evidence for a fundamental role in hippocampal information processing 
    Lehr, Andrew; Kumar, Arvind; Tezlaff, Christian; Hafting, Torkel; Fyhn, Marianne; Stöber, Tristan Manfred (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    Hippocampal region CA2 has received increased attention due to its importance in social recognition memory. While its specific function remains to be identified, there are indications that CA2 plays a major role in a variety ...
  • Ca2+ ions decrease adhesion between two (104) calcite surfaces as probed by Atomic Force Microscopy 
    Dziadkowiec, Joanna; Ban, Matea; Javadi, Shaghayegh; Jamtveit, Bjørn; Røyne, Anja (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    Solution composition-sensitive disjoining pressure acting between the mineral surfaces in fluid-filled granular rocks and materials controls their cohesion, facilitates the transport of dissolved species, and may sustain ...
  • Ca2+ signals in astrocytes facilitate spread of epileptiform activity 
    Heuser, Kjell; Nome, Cecilie; Pettersen, Klas; Åbjørsbråten, Knut Sindre; Jensen, Vidar; Tang, Wannan; Sprengel, Rolf; Taubøll, Erik; Nagelhus, Erlend Arnulf; Enger, Rune (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    Epileptic seizures are associated with increased astrocytic Ca2+ signaling, but the fine spatiotemporal kinetics of the ictal astrocyte–neuron interplay remains elusive. By using 2-photon imaging of awake head-fixed mice ...
  • Ca2+-mediated activation of ERK in hepatocytes by norepinephrine and prostaglandin F2α: role of calmodulin and src kinases 
    Melien, Øyvind; Nilssen, Laila S; Dajani, Olav F; Larsen Sand, Kristin; Iversen, Jens-Gustav; Sandnes, Dagny L; Christoffersen, Thoralf (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2002)
    Background Previous studies have shown that several agents that stimulate heptahelical G-protein coupled receptors activate the extracellular signal regulated kinases ERK1 (p44mapk) and ERK2 (p42mapk) in ...
  • Cabazitaxel-loaded Poly(2-ethylbutyl cyanoacrylate) nanoparticles improve treatment efficacy in a patient derived breast cancer xenograft. 
    Fusser, Markus; Øverbye, Anders; Pandya, Abhilash D.; Mørch, Ýrr Asbjørg; Borgos, Sven Even F.; Kildal, Wanja; Snipstad, Sofie; Sulheim, Einar; Fleten, Karianne Giller; Askautrud, Hanne Arenberg; Engebraaten, Olav; Flatmark, Kjersti; Iversen, Tore Geir; Sandvig, Kirsten; Skotland, Tore; Mælandsmo, Gunhild Mari (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    The effect of poly(2-ethyl-butyl cyanoacrylate) nanoparticles containing the cytotoxic drug cabazitaxel was studied in three breast cancer cell lines and one basal-like patient-derived xenograft model grown in the mammary ...
  • Cabazitaxel-loaded poly(alkyl cyanoacrylate) nanoparticles: Toxicity and changes in the proteome of breast, colon and prostate cancer cells. 
    Øverbye, Anders; Torgersen, Maria Lyngaas; Sønstevold, Tonje; Iversen, Tore Geir; Mørch, Ýrr Asbjørg; Skotland, Tore; Sandvig, Kirsten (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2021)
    Nanoparticles composed of poly(alkyl cyanoacrylate) (PACA) have shown great promise due to their biodegradability and high drug loading capacity. Development of optimal PACA nanocarriers requires detailed analysis of the ...
  • CADA: a teacher-facing learning analytics dashboard to foster teachers’ awareness of students’ participation and discourse patterns in online discussions 
    Kaliisa, Rogers; Dolonen, Jan Arild (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    Despite the potential of learning analytics (LA) to support teachers’ everyday practice, its adoption has not been fully embraced due to the limited involvement of teachers as co-designers of LA systems and interventions. ...
  • Caesarean section among referred and self-referred birthing women: a cohort study from a tertiary hospital, northeastern Tanzania 
    Sørbye, Ingvil K; Vangen, Siri; Oneko, Olola; Sundby, Johanne; Bergsjø, Per (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2011)
    Background The inequity in emergency obstetric care access in Tanzania is unsatisfactory. Despite an existing national obstetric referral system, many birthing women bypass referring facilities and go ...
  • Caesarean section and the association with migraine: a retrospective register-linked HUNT population cohort study 
    Kristoffersen, Espen Saxhaug; Børte, Sigrid; Hagen, Knut; Zwart, John-Anker; Winsvold, Bendik K S (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Objectives To evaluate the association between caesarean section and migraine in a population-based register-linked cohort study. Setting Data from the population-based Nord-Trøndelag Health Studies (HUNT2 and HUNT3) were ...
  • Caesarean section in Palestine using the Robson Ten Group Classification System: A population-based birth cohort study 
    Zimmo, Mohammed; Laine, Katariina; Hassan, Sahar J. A.; Böttcher, Bettina; Fosse, Erik; Ali, Hadil; Zimmo, Kaled; Falk, Ragnhild Sørum; Lieng, Marit; Vikanes, Åse (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    Objective: To analyse the current situation of caesarean section in Palestine using the Robson Ten Group Classification System (TGCS). Methods: The contributions of each group to the study population and to the overall ...
  • Calcar screws and adequate reduction reduced the risk of fixation failure in proximal humeral fractures treated with a locking plate: 190 patients followed for a mean of 3 years 
    Oppebøen, Sjur; Wikerøy, Annette K B; Fuglesang, Hendrik F S; Dolatowski, Filip C; Randsborg, Per-Henrik (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    Background Fixation of proximal humeral fractures (PHF) with locking plates has gained popularity over conservative treatment, but surgery may be complicated with infection, non-union, avascular necrosis ...