Browsing Institutt for informatikk by Author "Tønnessen, Theis"

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  • Identifying pathogenic processes by integrating microarray data with prior knowledge 
    Nygård, Ståle; Reitan, Trond; Clancy, Trevor; Nygaard, Vegard; Bjørnstad, Johannes; Skrbic, Biljana; Tønnessen, Theis; Christensen, Geir; Hovig, Eivind (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
    Background It is of great importance to identify molecular processes and pathways that are involved in disease etiology. Although there has been an extensive use of various high-throughput methods for this ...
  • The extracellular matrix proteoglycan lumican improves survival and counteracts cardiac dilatation and failure in mice subjected to pressure overload 
    Mohammadzadeh, Naiyereh; Lunde, Ida Gjervold; Andenæs, Kine; Strand, Mari Elen; Aronsen, Jan Magnus; Skrbic, Biljana; Marstein, Henriette; Bandlien, Caroline; Nygård, Ståle; Gorham, Joshua; Sjaastad, Ivar; Chakravarti, Shukti; Christensen, Geir Arve; Engebretsen, Kristin V Thunheim; Tønnessen, Theis (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    Left ventricular (LV) dilatation is a key step in transition to heart failure (HF) in response to pressure overload. Cardiac extracellular matrix (ECM) contains fibrillar collagens and proteoglycans, important for maintaining ...