Browsing Institutt for informatikk by Author "Fyhn, Marianne"

Now showing items 1-9 of 9

  • Alterations in schizophrenia-associated genes can lead to increased power in delta oscillations 
    Mäki-Marttunen, Tuomo; Krull, Florian; Bettella, Francesco; Hagen, Espen; Næss, Solveig; Ness, Torbjørn V; Moberget, Torgeir; Elvsåshagen, Torbjørn; Metzner, Christoph; Devor, Anna; Edwards, Andrew G.; Fyhn, Marianne; Djurovic, Srdjan; Dale, Anders; Andreassen, Ole Andreas; Einevoll, Gaute (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    Genome-wide association studies have implicated many ion channels in schizophrenia pathophysiology. Although the functions of these channels are relatively well characterized by single-cell studies, the contributions of ...
  • Biophysical Psychiatry—How Computational Neuroscience Can Help to Understand the Complex Mechanisms of Mental Disorders. 
    Mäki-Marttunen, Tuomo; Kaufmann, Tobias; Elvsåshagen, Torbjørn; Devor, Anna; Djurovic, Srdjan; Westlye, Lars Tjelta; Linne, Marja-Leena; Rietschel, Marcella; Schubert, Dirk; Borgwardt, Stefan; Efrim-Budisteanu, Magdalena; Bettella, Francesco; Halnes, Geir; Hagen, Espen; Næss, Solveig; Ness, Torbjørn V; Moberget, Torgeir; Metzner, Christoph; Edwards, Andrew G.; Fyhn, Marianne; Dale, Anders M.; Einevoll, Gaute T.; Andreassen, Ole Andreas (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    The brain is the most complex of human organs, and the pathophysiology underlying abnormal brain function in psychiatric disorders is largely unknown. Despite the rapid development of diagnostic tools and treatments in ...
  • CA2 beyond social memory: Evidence for a fundamental role in hippocampal information processing 
    Lehr, Andrew; Kumar, Arvind; Tezlaff, Christian; Hafting, Torkel; Fyhn, Marianne; Stöber, Tristan Manfred (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    Hippocampal region CA2 has received increased attention due to its importance in social recognition memory. While its specific function remains to be identified, there are indications that CA2 plays a major role in a variety ...
  • Combining biophysical modeling and deep learning for multielectrode array neuron localization and classification 
    Buccino, Alessio Paolo; Kordovan, Michael; Ness, Torbjørn V; Merkt, Benjamin; Häfliger, Philipp; Fyhn, Marianne; Cauwenberghs, Gert; Rotter, Stefan; Einevoll, Gaute (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    Neural circuits typically consist of many different types of neurons, and one faces a challenge in disentangling their individual contributions in measured neural activity. Classification of cells into inhibitory and ...
  • Differential Expression and Cell-Type Specificity of Perineuronal Nets in Hippocampus, Medial Entorhinal Cortex and Visual Cortex Examined in the Rat and Mouse 
    Lensjø, Kristian Kinden; Christensen, Ane Charlotte; Tennøe, Simen; Fyhn, Marianne; Hafting, Torkel (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    Perineuronal nets (PNNs) are specialized extracellular matrix (ECM) structures that condense around the soma and proximal dendrites of subpopulations of neurons. Emerging evidence suggests that they are involved in regulating ...
  • Experimental Pipeline (Expipe): A Lightweight Data Management Platform to Simplify the Steps From Experiment to Data Analysis 
    Lepperød, Mikkel Elle; Dragly, Svenn-Arne; Buccino, Alessio Paolo; Mobarhan, Milad; Malthe-Sørenssen, Anders; Hafting, Torkel; Fyhn, Marianne (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    As experimental neuroscience is moving toward more integrative approaches, with a variety of acquisition techniques covering multiple spatiotemporal scales, data management is becoming increasingly challenging for neuroscience ...
  • Open source modules for tracking animal behavior and closed-loop stimulation based on Open Ephys and Bonsai 
    Buccino, Alessio Paolo; Lepperød, Mikkel Elle; Dragly, Svenn-Arne; Häfliger, Philipp; Fyhn, Marianne; Hafting, Torkel (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    Objective: A major goal in systems neuroscience is to determine the causal relationship between neural activity and behavior. To this end, methods that combine monitoring neural activity, behavioral tracking, and targeted ...
  • Optogenetic pacing of medial septum parvalbumin-positive cells disrupts temporal but not spatial firing in grid cells 
    Lepperød, Mikkel Elle; Christensen, Ane Charlotte; Lensjø, Kristian Kinden; Buccino, Alessio Paolo; Yu, Jai; Fyhn, Marianne; Hafting, Torkel (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    Grid cells in the medial entorhinal cortex (MEC) exhibit remarkable spatial activity patterns with spikes coordinated by theta oscillations driven by the medial septal area (MSA). Spikes from grid cells progress relative ...
  • Selective neuromodulation and mutual inhibition within the CA3-CA2 system can prioritize sequences for replay 
    Støber, Tristan; Lehr, Andrew B; Hafting, Torkel; Kumar, Arvind; Fyhn, Marianne (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    To make optimal use of previous experiences, important neural activity sequences must be prioritized during hippocampal replay. Integrating insights about the interplay between CA3 and CA2, we propose a conceptual framework ...