dc.date.accessioned | 2013-03-12T12:37:23Z | |
dc.date.available | 2017-06-06T22:30:41Z | |
dc.date.issued | 2012 | en_US |
dc.date.submitted | 2012-04-01 | en_US |
dc.identifier.citation | Hasseleid, Bernt Filip K. Surgery for convexity meningiomas. Prosjektoppgave, University of Oslo, 2012 | en_US |
dc.identifier.uri | http://hdl.handle.net/10852/29351 | |
dc.description.abstract | Background:
Recently the relevance of Simpsons resection grade as a prognostic factor for recurrence of WHO grade I meningiomas was challenged, contradicting many previous scientific reports and traditional neurosurgical teaching.
Objective:
To study whether the predictive value of Simpson resection grade with respect to meningioma recurrence and overall survival is outdated or still valid.
Material & Methods:
All patients ≥16 years who underwent primary craniotomies for convexity meningiomas at the Oslo University affiliated hospitals (Rikshospitalet and Ullevål University Hospital) in the period 01.01.1990 – 27.01.2011 were included. Overall survival (OS) and retreatment-free survival (RFS) rates were related to patient- and surgery-specific factors.
Results:
Included in the study were 391 consecutive patients. Median age was 60.1 years (range 19 - 92). Female-to-male ratio was 2.1:1. WHO grade was grade I in 352 (90.3%), grade II in 22 (5.6%) and grade III in 16 (4.1%). Follow-up was 100%. Median follow-up time was 7.1 years (range 0.0 – 20.9 years) and total observation time was 3147 patient-years. The 1-, 5- and 10-year OS were 96%, 89% and 78%, respectively. Age, gender, WHO-grade and Simpson grade were significantly associated with OS. The 1-, 5- and 10-year RFS were 99%%, 94% and 90%, respectively. Simpson resection grade and WHO grade were significantly associated with RFS. Odds ratio for recurrence after Simpson resection grade 2/3 and 4/5 were 5.2 and 26.1 times higher than after Simpson grade 1 resection, respectively.
Conclusions:
Simpson grade 1 resection should still be the goal for convexity meningiomas. | eng |
dc.language.iso | eng | en_US |
dc.subject | kirurgi | |
dc.title | Surgery for convexity meningiomas : Simpson grade 1 resection should still be the goal | en_US |
dc.type | Master thesis | en_US |
dc.date.updated | 2012-10-09 | en_US |
dc.creator.author | Hasseleid, Bernt Filip K | en_US |
dc.subject.nsi | VDP::780 | en_US |
dc.identifier.bibliographiccitation | info:ofi/fmt:kev:mtx:ctx&ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&rft.au=Hasseleid, Bernt Filip K&rft.title=Surgery for convexity meningiomas&rft.inst=University of Oslo&rft.date=2012&rft.degree=Prosjektoppgave | en_US |
dc.identifier.urn | URN:NBN:no-31262 | en_US |
dc.type.document | Prosjektoppgave | en_US |
dc.identifier.duo | 153515 | en_US |
dc.contributor.supervisor | Eirik Helseth | en_US |
dc.identifier.fulltext | Fulltext https://www.duo.uio.no/bitstream/handle/10852/29351/2/Prosjekt-Hasseleid.pdf | |