dc.date.accessioned | 2013-03-12T12:33:18Z | |
dc.date.available | 2013-03-12T12:33:18Z | |
dc.date.issued | 2007 | en_US |
dc.date.submitted | 2007-02-07 | en_US |
dc.identifier.citation | Berntsen, Birgitte, Gupta, Ritika Ashok, . Daily oscillations of sweating in hyperhidrotic individuals before and after treatment with botulinum toxin A. Prosjektoppgave, University of Oslo, 2007 | en_US |
dc.identifier.uri | http://hdl.handle.net/10852/29087 | |
dc.description.abstract | Abstract
BACKGROUND: Primary focal hyperhidrosis is caused by excessive secretion by eccrine sweat glands, usually at axillae, palms and soles. The underlying mechanism is unclear. Botulinum toxin A is a highly efficient treatment for this condition. A subjective self-assessment scale has been shown to be a useful tool in assessing the variation in sweat levels before treatment. It has also been shown that treatment of hyperhidrosis with botulinum toxin A increases the patients’ quality of life. OBJECTIVES: To study the daily variations of sweating in hyperhidrotic individuals and how this affects quality of life (QOL) before and after treatment with botulinum toxin A, using a subjective self-assessment scale. METHODS: 18 patients with a history of hyperhidrosis (7 axillary, 5 palmar and 6 general) were studied. Each participant self-assessed rates of sweating for 7 days on an hourly basis using a subjective evaluation scale (SES) ranging from 0 to 10 before and one, three and six months after treatment with botulinum toxin A. The patients also recorded one VAS (Visual Analogue Scale) -QOL value before and after treatment. RESULTS: Following treatment, VAS-QOL increased in all patients (Median value before and after 5 and 9, respectively, p< 0,01), and there was also a reduction in sweating after one and three months in all patients (SES before = 4.2, SES 1 month = 0.8, SES 3 months = 0.9, p < 0.0001). After six months, the difference was not significant, but the values had not reached the pre-treatment level. Different patterns of sweating were observed before treatment, and most patients also showed the same pattern after treatment, but the values were lower. CONCLUSIONS: Successful treatment of hyperhidrosis with botulinum toxin A gives a significant increase in VAS-QOL and significantly decreases the sweat levels after one and three months. | nor |
dc.language.iso | eng | en_US |
dc.subject | hudsykdommer | |
dc.title | Daily oscillations of sweating in hyperhidrotic individuals before and after treatment with botulinum toxin A | en_US |
dc.type | Master thesis | en_US |
dc.date.updated | 2007-03-07 | en_US |
dc.creator.author | Berntsen, Birgitte | en_US |
dc.creator.author | Gupta, Ritika Ashok | en_US |
dc.subject.nsi | VDP::753 | en_US |
dc.identifier.bibliographiccitation | info:ofi/fmt:kev:mtx:ctx&ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&rft.au=Berntsen, Birgitte&rft.au=Gupta, Ritika Ashok&rft.title=Daily oscillations of sweating in hyperhidrotic individuals before and after treatment with botulinum toxin A&rft.inst=University of Oslo&rft.date=2007&rft.degree=Prosjektoppgave | en_US |
dc.identifier.urn | URN:NBN:no-14435 | en_US |
dc.type.document | Prosjektoppgave | en_US |
dc.identifier.duo | 52448 | en_US |
dc.contributor.supervisor | Anne Lene Krogstad | en_US |
dc.identifier.bibsys | 070300763 | en_US |
dc.identifier.fulltext | Fulltext https://www.duo.uio.no/bitstream/handle/10852/29087/4/Prosjektoppg.B.Berntsen%2CxR.A.Gupta.pdf | |