• Chen, Xiangjun; Badian, Reza A.; Hynne, Håvard; Amdal, Cecilie Delphin; Herlofson, Bente Brokstad; Utheim, Øygunn Aass; Westgaard, Kristine Løken; Fineide, Fredrik; Jensen, Janicke Liaaen; Utheim, Tor Paaske (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    Patients undergoing intensity-modulated radiotherapy (IMRT) for head and neck cancer may have increased incidence of dry eye disease and the exact mechanism is unclear. The present study aims to assess tear film and meibomian ...
  • Hynne, Håvard (Doctoral thesis / Doktoravhandling, 2022)
    Dry mouth and dry eyes are common findings, especially in subjects on multiple medications. Primary Sjögren's syndrome (pSS) also causes dry mouth and dry eyes, and radiotherapy due to head and neck cancer (HNC) is known ...
  • Aqrawi, Lara A.; Chen, Xiangjun; Hynne, Håvard; Amdal, Cecilie Delphin; Reppe, Sjur; Aass, Hans Christian Dalsbotten; Rykke, Morten; Hove, Lene Hystad; Young, Alix; Herlofson, Bente Brokstad; Westgaard, Kristine Løken; Utheim, Tor Paaske; Galtung, Hilde; Jensen, Janicke Liaaen (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Although radiotherapy is a common form of treatment for head and neck cancer, it may lead to tissue damage in the salivary and lacrimal glands, possibly affecting cytokine expression in the gland fluid of treated individuals. ...
  • Frigaard, Julie Mari; Hynne, Håvard; Jensen, Janicke Liaaen (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    Dry mouth is a common complaint with unmet treatment needs, reflected by the fact that more than 500 trials are registered on ClinicalTrials.gov. Comparisons across studies, however, are difficult as inclusion criteria ...
  • Frigaard, Julie Mari; Hynne, Håvard; Randsborg, Karoline; Mellin-Olsen, Tonje; Young, Alix; Rykke, Morten; Singh, Preet Bano; Hove, Lene Hystad; Hofgaard, Anne Kristine; Jensen, Janicke Liaaen (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    Background Patients suffering from psychiatric disorders face many difficulties due to their condition, medications and lifestyle. Oral health and nutrition may be affected, further complicating their lives. Our aim was ...
  • Chen, Xiangjun; Badian, Reza; Hynne, Håvard; Tashbayev, Behzod; Hove, Lene Hystad; Jensen, Janicke Liaaen; Utheim, Tor Paaske (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    Analyses of meibography may help in the diagnosis, prevention, and management of meibomian gland dysfunction (MGD). However, there is currently a paucity of data regarding meibography analyses in the young elderly populations ...
  • Westgaard, Kristine Løken; Hynne, Håvard; Amdal, Cecilie Delphin; Young, Alix; Singh, Preet Bano; Chen, Xiangjun; Rykke, Morten; Hove, Lene Hystad; Aqrawi, Lara A.; Utheim, Tor Paaske; Herlofson, Bente Brokstad; Jensen, Janicke Liaaen (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    A broader understanding of oral and ocular late effects in head and neck cancer (HNC) patients who underwent intensity-modulated radiotherapy (IMRT) may provide valuable information in follow-up and improve quality of life. ...
  • Hynne, Håvard; Aqrawi, Lara A.; Jensen, Janicke Liaaen; Thiede, Bernd; Palm, Øyvind; Amdal, Cecilie Delphin; Westgaard, Kristine Løken; Herlofson, Bente Brokstad; Utheim, Tor Paaske; Galtung, Hilde (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    Patients with head and neck cancer (HNC) and patients with primary Sjögren’s syndrome (pSS) may exhibit similar symptoms of dry mouth and dry eyes, as a result of radiotherapy (RT) or a consequence of disease progression. ...
  • Hynne, Håvard; Mørk Sandås, Elise; Elgstøen, Katja B. Prestø; Rootwelt, Helge; Utheim, Tor Paaske; Galtung, Hilde; Jensen, Janicke Liaaen (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    The etiology of dry mouth conditions is multi-faceted. Patients radiated after head and neck cancer (HNC) and those with primary Sjögren’s syndrome (pSS) share many of the same symptoms despite different causes. With the ...
  • Fineide, Fredrik; Tashbayev, Behzod; Elgstøen, Katja B. Prestø; Sandås, Elise Mørk; Rootwelt, Helge; Hynne, Håvard; Chen, Xiangjun; Ræder, Sten; Vehof, Jelle; Dartt, Darlene Ann; Jensen, Janicke Liaaen; Utheim, Tor Paaske (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    Accurate diagnosis of dry eye disease (DED) is challenging, and even today there is no gold standard biomarker of DED. Hypothesis-free global metabolomic studies of tears from DED patients have great potential to discover ...
  • Hynne, Håvard; Tashbayev, Behzod; Diep, My Tien; Sødal, Anne Thea Tveit; Badian, Reza A.; Chen, Xiangjun; Lai, Xiaoran; Utheim, Tor Paaske; Hove, Lene Hystad; Jensen, Janicke Liaaen (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    In the present study, the relationship between dry eyes and dry mouth was explored in 150 65-year-old subjects randomly selected from the general population in Oslo, Norway. The number of drugs, including xerogenic drugs, ...