Browsing Det odontologiske fakultet by Author "Dembic, Zlatko"
Now showing items 1-14 of 14
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Eftedal, Randi Krog; Vrgoc, Goran; Jotanovic, Zdravko; Dembic, Zlatko (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)We studied the genetic epidemiology of primary large‐joint (hip and knee) osteoarthritis (OA), in order to find disease risk factors by a candidate‐gene approach. We used case–control study in the Croatian Caucasian ...
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Dembic, Zlatko (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)Through novel methodologies, including both basic and clinical research, progress has been made in the therapy of solid cancer. Recent innovations in anticancer therapies, including immune checkpoint inhibitor biologics, ...
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Etokebe, Godfrey; Zienolddiny, Shanbeh; Kupanovac, Zeljko; Enersen, Morten; Balen, Sanja; Flego, Velkjo; Bulat-Kardum, Ljiljana; Radojčić-Badovinac, Anđelka; Skaug, Vidar; Bakke, Per S.; Haugen, Aage; Dembic, Zlatko (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)We analyzed for associations between a variable number of tandem repeat (VNTR) polymorphism in the Family with sequence similarity 46, member A (FAM46A) gene and a single nucleotide polymorphism (rs3117582) in the ...
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Etokebe, Godfrey; Bulat-Kardum, Ljiljana; Munthe, Ludvig Andre; Balen, Sanja; Dembic, Zlatko (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)We analyzed for association between the Family with sequence similarity 46, member A (FAM46A) gene (located on chromosome 6q14.1), BCL2-Associated Athanogene 6 (BAG6) gene (located on chromosome 6p21.3) and tuberculosis ...
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Dembic, Zlatko (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)The Integrity model proposes that the adaptive immune response defends, protects and keeps vigilance over the unity of an organism. These functions conceptually rely on three signals that can explain them. All signals have ...
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Etokebe, Godfrey; Axellson, Stefan; Svaerd, Niels Henrik; Storhaug, Kari; Dembic, Zlatko (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2008)We have developed a dual probe quantitative PCR (qPCR ) mini array enabling a more accurate analysis of the relationship between copy number variants (CNVs) and other genomic features in specific areas. We used it to map ...
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Vrbanec, Jurica; Lederer-Dembic, Petra; Bulat-Kardum, Ljiljana; Balen, Sanja; Eftedal, Randi Krog; Dembic, Zlatko (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)Regarding genetic predisposition to tuberculosis, we suggest that the maximal risk for clinical manifestation requires complementation of sub-risks divided among the hallmarks of the disease. Clinical tuberculosis would ...
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Haabeth, Ole Audun; Tveita, Anders; Fauskanger, Marte Hotvedt; Schjesvold, Fredrik Hellem; Lorvik, Kristina Berg; Hofgaard, Peter Olaf; Omholt, Hilde; Munthe, Ludvig Andre; Dembic, Zlatko; Corthay, Alexandre; Bogen, Bjarne (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)CD4+ T cells contribute to tumor eradication, even in the absence of CD8+ T cells. Cytotoxic CD4+ T cells can directly kill MHC class II positive tumor cells. More surprisingly, CD4+ T cells can indirectly eliminate tumor ...
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Dembic, Zlatko (Chapter / Bokkapittel / SubmittedVersion, 2012)The workings of the immune system, in philosophical terms, follow integrity principle, which I regard as a sum of homeostatic (integrity preservation) and analytic (integration) functions of tissues within an organism. It ...
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Kaarvatn, Marikken Heiland; Eftedal, Randi Krog; Vrbanec, Jurica; Jotanovic, Zdravko; Etokebe, Godfrey; Sanja, Balen; Ana, Kulic; Dembic, Zlatko (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2012)Breast cancer has a complex genetic susceptibility. Innate and adaptive immunity can additionally increase the genetic risk to breast cancer development. We typed polymorphisms in the genes of the interleukin(IL)-1 and ...
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Dembic, Zlatko (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)The Standard model of T cell recognition asserts that T cell receptor (TCR) specificities are positively and negatively selected during ontogeny in the thymus and that peripheral T cell repertoire has mild self‐major ...
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Armingohar, Zahra; Jørgensen, Jørgen J.; Kristoffersen, Anne Karin; Schenck, Karl; Dembic, Zlatko (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)Background: Chronic periodontitis (CP), atherosclerotic and aortic aneurysmal vascular diseases (VD) are chronic inflammatory conditions with multifactorial etiologies, including involvement of predisposing genetic factors. ...
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Cohn, Melvin; Anderson, Colin C.; Dembic, Zlatko (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)There is a sharp difference in how one views TCR structure-function behavior dependent on whether its recognition of MHC-encoded restriction elements (R) is germline selected or somatically generated. The generally accepted ...
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Eftedal, Randi Krog; Jotanovic, Zdravko; Balen, Sanja; Dembic, Zlatko (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)Aim: We studied genetic epidemiology of primary large-joint (hip and knee) osteoarthritis (OA), in order to find disease risk factors by a candidate-gene approach. We used TNFA gene SNP rs1800629 in a case-control study ...