Browsing Det odontologiske fakultet by Author "Søland, Tine Merete"
Now showing items 1-16 of 16
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Bjerkli, Inger-Heidi; Hadler-Olsen, Elin Synnøve; Nginamau, Elisabeth Sivy; Laurvik, Helene; Søland, Tine Merete; Costea, Daniela Elena; Uhlin-Hansen, Lars; Steigen, Sonja Eriksson (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)We wanted to evaluate the prognostic value of common histopathological variables in a large cohort of patients with cancer in the mobile tongue as such information can be important for treatment stratification of the ...
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Juvkam, Inga; Zlygosteva, Olga; Arous, Delmon; Galtung, Hilde; Malinen, Eirik; Søland, Tine Merete; Edin, Nina Frederike Jeppesen (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)Abstract Radiotherapy (RT) of head and neck (H&N) cancer is known to cause both early- and late-occurring toxicities. To better appraise normal tissue responses and their dependence on treatment parameters ...
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Zlygosteva, Olga; Juvkam, Inga; Arous, Delmon; Sitarz, Mateusz; Sørensen, Brita Singers; Ankjærgaard, Christina; Andersen, Claus E.; Galtung, Hilde; Søland, Tine Merete; Edin, Nina Frederike Jeppesen; Malinen, Eirik (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)Background The purpose of this study was to investigate acute normal tissue responses in the head and neck region following proton- or X-irradiation of a murine model. Materials and methods Female C57BL/6J mice were ...
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Mazagão Guerreiro, Eduarda; Øvstebø, Reidun; Thiede, Bernd; Costea, Daniela Elena; Søland, Tine Merete; Galtung, Hilde (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)Extracellular vesicles (EVs), are important for intercellular communication in both physiological and pathological processes. To explore the potential of cancer derived EVs as disease biomarkers for diagnosis, monitoring, ...
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Pandey, Sushma; Søland, Tine Merete; Bjerkli, Inger-Heidi; Sand, Lars Peter; Petersen, Fernanda Cristina; Costea, Daniela Elena; Senguven, Burcu; Sapkota, Dipak (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)Background This study aimed to evaluate the prognostic significance of expression levels of involucrin (IVL), cytokeratin (CK)-10 and -13 at different intratumor sites (tumor center and invading area) of oral tongue ...
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Zlygosteva, Olga; Juvkam, Inga; Aass, Hans Christian; Galtung, Hilde; Søland, Tine Merete; Malinen, Eirik; Edin, Nina Frederike Jeppesen (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)Cytokines are mediators of inflammation that could lead to fibrosis. The aim was to monitor cytokine levels in saliva and serum after locally fractionated radiotherapy of the head and neck in mice and investigate associations ...
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Guerreiro, Eduarda; Vestad, Beate; Steffensen, Lilly Alice; Aass, Hans Christian Dalsbotten; Saeed, Muhammad; Øvstebø, Reidun; Costea, Daniela Elena; Galtung, Hilde; Søland, Tine Merete (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)Extracellular vesicles (EVs) are a heterogeneous population of biological particles released by cells. They represent an attractive source of potential biomarkers for early detection of diseases such as cancer. However, ...
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Sapkota, Dipak; Sharma, Sunita; Søland, Tine Merete; Braz-Silva, Paulo; Teh, Muy-Teck (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)Objective Besides angiotensin converting enzyme 2 (ACE2), an active involvement of proteases (FURIN and/or TMPRSS2) is important for cellular entry of SARS-CoV-2. Therefore, a simultaneous expression profiling of entry ...
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Steigen, Sonja E; Søland, Tine Merete; Nginamau, Elisabeth Sivy; Laurvik, Helene; Costea, Daniela-Elena; Johannessen, Anne Christine; Jebsen, Peter Wilhelm; Bjerkli, Inger-Heidi; Uhlin-Hansen, Lars; Hadler-Olsen, Elin Synnøve (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)Background Numerous studies have been presented on histological grading of oral squamous cell carcinomas (OSCC) for predicting survival, but uncertainty of their usefulness rises due to discordances of results. A scoring ...
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Søland, Tine Merete; Bjerkli, Inger-Heidi; Georgsen, Jeanette B; Schreurs, Olaf Joseph Franciscus; Jebsen, Peter Wilhelm; Laurvik, Helene; Sapkota, Dipak (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)Abstract Objectives: The presence of and the causative role of high-risk human papilloma virus (HPV) is a subject of controversy in oral squamous cell carcinoma (OSCC). The disagreement can be related to the misclassification ...
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Sapkota, Dipak; Vallenari, Evan Michael; Tamatam, Dhanalakshmi; Schreurs, Olaf Joseph Franciscus; Pandey, Sushma; Søland, Tine Merete; Costea, Daniela Elena; Tokozlu, Burcu; aasheim, Hans-Christian (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)Ephrin-B1,-B2 and -B3 proteins share a high degree of sequence similarity. Investigation of these proteins as putative prognostic markers in human cancers including oral squamous cell carcinoma (OSCC) has been limited by ...
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Haugsten, Helene Rygvold; Kristoffersen, Anne Karin; Haug, Trude Marie; Søland, Tine Merete; Øvstebø, Reidun; Aass, Hans Christian; Enersen, Morten; Galtung, Hilde (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)Periodontitis is an inflammatory condition caused by bacteria and represents a serious health problem worldwide as the inflammation damages the supporting tissues of the teeth and may predispose to systemic diseases. ...
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Juvkam, Inga Solgård; Zlygosteva, Olga; Sitarz, Mateusz; Thiede, Bernd; Sørensen, Brita Singers; Malinen, Eirik; Edin, Nina Frederike Jeppesen; Søland, Tine Merete; Galtung, Hilde (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)Extracellular vesicles (EVs) are membrane-bound particles released from cells, and their cargo can alter the function of recipient cells. EVs from X-irradiated cells have been shown to play a likely role in non-targeted ...
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Søland, Tine Merete; Solhaug, Maren Bråten; Bjerkli, Inger-Heidi; Schreurs, Olaf Joseph Franciscus; Sapkota, Dipak (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)Krüppel-like factor 4 (KLF4) is a zinc-finger transcription factor involved in inflammation, cancer development, and progression. However, the relationship between KLF4, inflammation, and prognosis in oral cancer is not ...
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Sofizadeh, Narmin; Bjerkehagen, Bodil; Solheim, Tore Torsteinson; Sapkota, Dipak; Søland, Tine Merete (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)Introduction To assure knowledge and skills in diagnostic work of oral diseases a continuously updated curriculum is essential. The first aim of the present study was to evaluate the spectrum and frequency of oral ...
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Bjerkli, Inger-Heidi; Laurvik, Helene; Nginamau, Elisabeth Sivy; Søland, Tine Merete; Costea, Daniela Elena; Hov, Håkon; Uhlin-Hansen, Lars; Hadler-Olsen, Elin Synnøve; Steigen, Sonja Eriksson (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)Background The majority of oral cavity cancers arise in the oral tongue. The aim of this study was to evaluate the prognostic value of tumor budding in oral tongue squamous cell carcinoma, both as a separate variable ...