Browsing Det odontologiske fakultet by Author "Potempa, Jan"
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Olsen, Ingar; Singhrao, Sim K; Potempa, Jan (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)Periodontitis, rheumatoid arthritis (RA), atherosclerosis (AS), and Alzheimer’s disease (AD) are examples of complex human diseases with chronic inflammatory components in their etiologies. The initial trigger of inflammation ...
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Siddiqui, Huma; Yoder-Himes, Deborah Ruth; Mizgalska, Danuta; Nguyen, Ky-Anh; Potempa, Jan; Olsen, Ingar (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)Porphyromonas gingivalis is considered a major etiologic agent in adult periodontitis. Gingipains are among its most important virulence factors, but their release is unique in strain HG66. We present the genome sequence ...
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Olsen, Ingar; Potempa, Jan (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)Gingipains are the major virulence factors of Porphyromonas gingivalis, the main periodontopathogen. It is expected that inhibition of gingipain activity in vivo could prevent or slow down the progression of adult ...