Browsing Det odontologiske fakultet by Author "Jackson, Catherine"

Now showing items 1-11 of 11

  • A Hyaluronan Hydrogel Scaffold for Culture of Human Oral Mucosal Epithelial Cells in Limbal Stem-Cell Therapy 
    Yazdani, Mazyar; Shahdafar, Aboulghassem; Jackson, Catherine; Utheim, Tor Paaske (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    Hyaluronan (HA), a major component of the extracellular matrix, plays a key role in cell proliferation, growth, survival, polarization and differentiation. We investigated the optimization of a HA hydrogel scaffold for ...
  • Concise review: Altered versus unaltered amniotic membrane as a substrate for limbal epithelial cells 
    Utheim, Tor Paaske; Utheim, Øygunn Aass; Salvanos, Panagiotis; Jackson, Catherine; Schrader, Stefan; Geerling, Gerd; Sehic, Amer (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2018)
    Limbal stem cell deficiency (LSCD) can result from a variety of corneal disorders, including chemical and thermal burns, infections, and autoimmune diseases. The symptoms of LSCD may include irritation, epiphora, blepharospasms, ...
  • Coordinated collective migration and asymmetric cell division in confluent human keratinocytes without wounding 
    Lång, Emma Helena; Polec, Anna; Lång, Anna Ulrika; Valk, Marijke; Blicher, Pernille; Rowe, Alexander D.; Tønseth, Kim Alexander; Jackson, Catherine; Utheim, Tor Paaske; Janssen, Liesbeth M.C.; Eriksson, Jens Christian; Bøe, Stig Ove (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    Epithelial sheet spreading is a fundamental cellular process that must be coordinated with cell division and differentiation to restore tissue integrity. Here we use consecutive serum deprivation and re-stimulation to ...
  • Cultured epidermal stem cells in regenerative medicine 
    Jackson, Catherine; Tønseth, Kim Alexander; Utheim, Tor Paaske (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    Transplantation of cultured epidermal cell sheets (CES) has long been used to treat patients with burns, chronic wounds, and stable vitiligo. In patients with large area burns this can be a life-saving procedure. The ...
  • Effect of storage temperature on cultured epidermal cell sheets stored in xenobiotic-free medium 
    Jackson, Catherine; Aabel, Peder; Eidet, Jon Roger; Messelt, Edvard Berger; Lyberg, Torstein; Von Unge, Magnus; Utheim, Tor Paaske (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
    Cultured epidermal cell sheets (CECS) are used in regenerative medicine in patients with burns, and have potential to treat limbal stem cell deficiency (LSCD), as demonstrated in animal models. Despite widespread use, ...
  • Effect of Storage Temperature on Structure and Function of Cultured Human Oral Keratinocytes 
    Islam, Rakibul; Jackson, Catherine; Eidet, Jon Roger; Messelt, Edward B.; Corraya, Rima Maria; Lyberg, Torstein; Griffith, May; Dartt, Darlene A.; Utheim, Tor Paaske (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
    Purpose/Aims To assess the effect of storage temperature on the viability, phenotype, metabolism, and morphology of cultured human oral keratinocytes (HOK). Materials and Methods Cultured HOK cells were stored in HEPES- ...
  • High Throughput Screening of Additives Using Factorial Design to Promote Survival of Stored Cultured Epithelial Sheets 
    Reppe, Sjur; Jackson, Catherine; Ringstad, Håkon; Tønseth, Kim Alexander; Bakke, Hege Gilbø; Eidet, Jon Roger; Utheim, Tor Paaske (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    There is a need to optimize storage conditions to preserve cell characteristics during transport of cultured cell sheets from specialized culture units to distant hospitals. In this study, we aimed to explore a method to ...
  • Hyaluronan-Based Hydrogel Scaffolds for Limbal Stem Cell Transplantation: A Review 
    Yazdani, Mazyar; Shahdafar, Aboulghassem; Jackson, Catherine; Utheim, Tor Paaske (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    Hyaluronan (HA), also termed hyaluronic acid or hyaluronate, is a major component of the extracellular matrix. This non-sulfated glycosaminoglycan plays a key role in cell proliferation, growth, survival, polarization, and ...
  • Improvement of Storage Medium for Cultured Human Retinal Pigment Epithelial Cells Using Factorial Design 
    Pasovic, Lara; Utheim, Tor Paaske; Reppe, Sjur; Khan, Ayyad Ahmad Zartasht; Jackson, Catherine; Thiede, Bernd; Berg, Jens Petter; Messelt, Edvard Berger; Eidet, Jon Roger (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    Storage of human retinal pigment epithelium (hRPE) can contribute to the advancement of cell-based RPE replacement therapies. The present study aimed to improve the quality of stored hRPE cultures by identifying storage ...
  • Sericin-induced melanogenesis in cultured retinal pigment epithelial cells is associated with elevated levels of hydrogen peroxide and inflammatory proteins 
    Khan, Ayyad Ahmad Zartasht; Jackson, Catherine; Utheim, Tor Paaske; Reppe, Sjur; Sapkota, Dipak; Olstad, Ole Kristoffer; Thiede, Bernd; Eidet, Jon Roger (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    We previously demonstrated that the silk protein sericin promotes pigmentation of retinal pigment epithelium (RPE) by activating the NF-κB pathway. Among numerous agents, NF-κB can be activated by hydrogen peroxide. In the ...
  • Simple limbal epithelial transplantation: Current status and future perspectives: Concise review 
    Jackson, Catherine; Ernø, Inger Thea Myklebust; Ringstad, Håkon; Tønseth, Kim Alexander; Dartt, Darlene Ann; Utheim, Tor Paaske (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Damage to limbal stem cells as a result of injury or disease can lead to limbal stem cell deficiency (LSCD). This disease is characterized by decreased vision that is often painful and may progress to blindness. Clinical ...