Browsing Det odontologiske fakultet by Author "Eidet, Jon Roger"

Now showing items 1-17 of 17

  • Concise Review: Comparison of Culture Membranes Used for Tissue Engineered Conjunctival Epithelial Equivalents 
    Eidet, Jon Roger; Dartt, Darlene A.; Utheim, Tor Paaske (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
    The conjunctival epithelium plays an important role in ensuring the optical clarity of the cornea by providing lubrication to maintain a smooth, refractive surface, by producing mucins critical for tear film stability and ...
  • Concise Review: Considering Optimal Temperature for Short-Term Storage of Epithelial Cells 
    Khan, Ayyad Ahmad Zartasht; Utheim, Tor Paaske; Jackson, Catherine Joan; Tønseth, Kim Alexander; Eidet, Jon Roger (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    Transplantation of novel tissue-engineered products using cultured epithelial cells is gaining significant interest. While such treatments can readily be provided at centralized medical centers, delivery to patients at ...
  • Dry Eye Disease Patients with Xerostomia Report Higher Symptom Load and Have Poorer Meibum Expressibility 
    Fostad, Ida Grunnan; Eidet, Jon Roger; Utheim, Tor Paaske; Ræder, Sten; Lagali, Neil; Messelt, Edvard Berger; Dartt, Darlene Ann (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
    The purpose of the study was to investigate if xerostomia (dry mouth) is associated with symptoms and signs of dry eye disease (DED). At the Norwegian Dry Eye Clinic, patients with symptomatic DED with different etiologies ...
  • Effect of storage temperature on cultured epidermal cell sheets stored in xenobiotic-free medium 
    Jackson, Catherine; Aabel, Peder; Eidet, Jon Roger; Messelt, Edvard Berger; Lyberg, Torstein; Von Unge, Magnus; Utheim, Tor Paaske (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
    Cultured epidermal cell sheets (CECS) are used in regenerative medicine in patients with burns, and have potential to treat limbal stem cell deficiency (LSCD), as demonstrated in animal models. Despite widespread use, ...
  • Effect of Storage Temperature on Key Functions of Cultured Retinal Pigment Epithelial Cells 
    Pasovic, Lara; Eidet, Jon Roger; Brusletto, Berit Sletbakk; Lyberg, Torstein; Utheim, Tor Paaske (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
    Purpose. Replacement of the diseased retinal pigment epithelium (RPE) with cells capable of performing the specialized functions of the RPE is the aim of cell replacement therapy for treatment of macular degenerative ...
  • Effect of Storage Temperature on Structure and Function of Cultured Human Oral Keratinocytes 
    Islam, Rakibul; Jackson, Catherine; Eidet, Jon Roger; Messelt, Edward B.; Corraya, Rima Maria; Lyberg, Torstein; Griffith, May; Dartt, Darlene A.; Utheim, Tor Paaske (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
    Purpose/Aims To assess the effect of storage temperature on the viability, phenotype, metabolism, and morphology of cultured human oral keratinocytes (HOK). Materials and Methods Cultured HOK cells were stored in HEPES- ...
  • Effect of transportation on cultured limbal epithelial sheets for worldwide treatment of limbal stem cell deficiency 
    Utheim, Øygunn Aass; Lyberg, Torstein; Eidet, Jon Roger; Ræder, Sten; Sehic, Amer; Roald, Borghild; Messelt, Edvard Berger; De La Paz, María Fidéliz; Dartt, Darlene Ann; Utheim, Tor Paaske (Journal article / Tidsskriftartikkel / PublisedVersion; Peer reviewed, 2018)
    Limbal stem cell deficiency can be treated with transplantation of cultured human limbal epithelial cells (LEC). It can be advantageous to produce LEC in centralized labs and thereafter ship them to eye clinics. The present ...
  • Effects of explant size on epithelial outgrowth, thickness, stratification, ultrastructure and phenotype of cultured limbal epithelial cells 
    Utheim, Øygunn Aass; Pasovic, Lara; Ræder, Sten; Eidet, Jon Roger; Fostad, Ida; Sehic, Amer; Roald, Borghild; de la Paz, Maria Fideliz; Lyberg, Torstein; Dartt, Darlene A.; Utheim, Tor Paaske (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    Purpose Transplantation of limbal stem cells is a promising therapy for limbal stem cell deficiency. Limbal cells can be harvested from either a healthy part of the patient’s eye or the eye of a donor. Small explants are ...
  • High Throughput Screening of Additives Using Factorial Design to Promote Survival of Stored Cultured Epithelial Sheets 
    Reppe, Sjur; Jackson, Catherine; Ringstad, Håkon; Tønseth, Kim Alexander; Bakke, Hege Gilbø; Eidet, Jon Roger; Utheim, Tor Paaske (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    There is a need to optimize storage conditions to preserve cell characteristics during transport of cultured cell sheets from specialized culture units to distant hospitals. In this study, we aimed to explore a method to ...
  • Improvement of Storage Medium for Cultured Human Retinal Pigment Epithelial Cells Using Factorial Design 
    Pasovic, Lara; Utheim, Tor Paaske; Reppe, Sjur; Khan, Ayyad Ahmad Zartasht; Jackson, Catherine; Thiede, Bernd; Berg, Jens Petter; Messelt, Edvard Berger; Eidet, Jon Roger (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    Storage of human retinal pigment epithelium (hRPE) can contribute to the advancement of cell-based RPE replacement therapies. The present study aimed to improve the quality of stored hRPE cultures by identifying storage ...
  • Optimization of Storage Temperature for Cultured ARPE-19 Cells 
    Pasovic, Lara; Utheim, Tor Paaske; Maria, Rima; Lyberg, Torstein; Messelt, Edward B.; Aabel, Peder; Chen, Dong Feng; Chen, Xiangjun; Eidet, Jon Roger (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
    Purpose. The establishment of future retinal pigment epithelium (RPE) replacement therapy is partly dependent on the availability of tissue-engineered RPE cells, which may be enhanced by the development of suitable storage ...
  • Reliability of corneal dynamic scheimpflug analyser measurements in virgin and post-PRK eyes 
    Chen, Xiangjun; Stojanovic, Aleksandar; Hua, Yanjun; Eidet, Jon Roger; Hu, Di; Wang, Jingting; Utheim, Tor Paaske (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
    Purpose To determine the measurement reliability of CorVis ST, a dynamic Scheimpflug analyser, in virgin and post-photorefractive keratectomy (PRK) eyes and compare the results between these two groups. Methods Forty ...
  • Seasonal variations in presenting symptoms and signs of dry eye disease in Norway 
    Eidet, Jon Roger; Chen, Xiangjun; Ræder, Sten; Badian, Reza; Utheim, Tor Paaske (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    Abstract The study investigated the seasonal variations of presenting symptoms and signs of dry eye disease (DED) in Norway. 652 consecutive DED patients examined between August 2012 and May 2015 in Oslo, Norway, were ...
  • Sericin-induced melanogenesis in cultured retinal pigment epithelial cells is associated with elevated levels of hydrogen peroxide and inflammatory proteins 
    Khan, Ayyad Ahmad Zartasht; Jackson, Catherine; Utheim, Tor Paaske; Reppe, Sjur; Sapkota, Dipak; Olstad, Ole Kristoffer; Thiede, Bernd; Eidet, Jon Roger (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    We previously demonstrated that the silk protein sericin promotes pigmentation of retinal pigment epithelium (RPE) by activating the NF-κB pathway. Among numerous agents, NF-κB can be activated by hydrogen peroxide. In the ...
  • Serum-Free and Xenobiotic-Free Preservation of Cultured Human Limbal Epithelial Cells 
    Utheim, Øygunn Aass; Islam, Rakibul; Lyberg, Torstein; Roald, Borghild; Eidet, Jon Roger; de la Paz, Maria; Dartt, Darlene A.; Raeder, Sten; Utheim, Tor Paaske (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
    Aim/Purpose of the Study To develop a one-week storage method, without serum and xenobiotics, that would maintain cell viability, morphology, and phenotype of cultured human limbal epithelial sheets. Materials and Methods ...
  • Storage temperature alters the expression of differentiation-related genes in cultured oral keratinocytes 
    Utheim, Tor Paaske; Islam, Rakibul; Fostad, Ida Grunnan; Eidet, Jon Roger; Sehic, Amer; Olstad, Ole Kristoffer; Dartt, Darlene A.; Messelt, Edvard Berger; Griffith, May; Pasovic, Lara (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
    Purpose Storage of cultured human oral keratinocytes (HOK) allows for transportation of cultured transplants to eye clinics worldwide. In a previous study, one-week storage of cultured HOK was found to be superior with ...
  • The silk protein sericin promotes viability of ARPE-19 and induced pluripotent stem cell-derived retinal pigment epithelial cells in vitro 
    Khan, Ayyad Ahmad Zartasht; Utheim, Tor Paaske; Moe, Morten Carsten; Aass, Hans Christian Dalsbotten; Sapkota, Dipak; Vallenari, Evan Michael; Eidet, Jon Roger (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2020)
    Purpose Maintaining mature and viable retinal pigment epithelial cells (RPE) in vitro has proven challenging. Investigating compounds that can promote RPE-viability and maturation is motivated by RPE transplantation ...