Browsing Øvrige samlinger by Author "Eyfjörd, Jórunn Erla"

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  • Somatic mutations reveal asymmetric cellular dynamics in the early human embryo 
    Ju, Young Seok; Martincorena, Inigo; Gerstung, Moritz; Petljak, Mia; Alexandrov, Ludmil B.; Rahbari, Raheleh; Wedge, David C.; Davies, Helen R.; Ramakrishna, Manasa; Fullam, Anthony; Martin, Sancha; Alder, Christopher; Patel, Nikita; Gamble, Steve; O'Meara, Sarah; Giri, DIlip D.; Sauer, Torill; Pinder, Sarah E.; Purdie, Colin A.; Borg, Åke; Stunnenberg, Henk; Van De Vijver, Marc; Tan, Benita K.T.; Caldas, Carlos; Tutt, Andrew; Ueno, Naoto T.; Van 't Veer, Laura J.; Martens, John W.M.; Sotiriou, Christos; Knappskog, Stian; Span, Paul N.; Lakhani, Sunil R.; Eyfjörd, Jórunn Erla; Børresen-Dale, Anne-Lise; Richardson, Andrea; Thompson, Alastair M.; Viari, Alain; Hurles, Matthew E.; Nik-Zainal, Serena; Campbell, Peter J.; Stratton, Michael R. (Journal article / Tidsskriftartikkel / SubmittedVersion, 2017)
    Somatic cells acquire mutations throughout the course of an individual’s life. Mutations occurring early in embryogenesis are often present in a substantial proportion of, but not all, cells in postnatal humans and thus ...