Browsing Det medisinske fakultet by Author "Fei, Liangru"

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  • Comprehensive characterization of the embryonic factor LEUTX 
    Gawriyski, Lisa; Jouhilahti, Eeva-Mari; Yoshihara, Masahito; Fei, Liangru; Weltner, Jere; Airenne, Tomi T.; Trokovic, Ras; Bhagat, Shruti; Tervaniemi, Mari H.; Murakawa, Yasuhiro; Salokas, Kari; Liu, Xiaonan; Miettinen, Sini; Bürglin, Thomas R.; Sahu, Biswajyoti; Otonkoski, Timo; Johnson, Mark S.; Katayama, Shintaro; Varjosalo, Markku; Kere, Juha (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    The paired-like homeobox transcription factor LEUTX is expressed in human preimplantation embryos between the 4- and 8-cell stages, and then silenced in somatic tissues. To characterize the function of LEUTX, we performed ...
  • Transposable elements as tissue-specific enhancers in cancers of endodermal lineage 
    Karttunen, Konsta; Patel, Divyesh; Xia, Jihan; Fei, Liangru; Palin, Kimmo; Aaltonen, Lauri; Sahu, Biswajyoti (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    Abstract Transposable elements (TE) are repetitive genomic elements that harbor binding sites for human transcription factors (TF). A regulatory role for TEs has been suggested in embryonal development and diseases such ...