Browsing Det medisinske fakultet by Author "Fagny, Maud"

Now showing items 1-4 of 4

  • Identification of Key Tissue-Specific, Biological Processes by Integrating Enhancer Information in Maize Gene Regulatory Networks 
    Fagny, Maud; Kuijjer, Marieke Lydia; Stam, Maike; Joets, Johann; Turc, Olivier; Rozière, Julien; Pateyron, Stéphanie; Venon, Anthony; Vitte, Clémentine (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Enhancers are key players in the spatio-temporal coordination of gene expression during numerous crucial processes, including tissue differentiation across development. Characterizing the transcription factors (TFs) and ...
  • Nongenic cancer-risk SNPs affect oncogenes, tumour-suppressor genes, and immune function 
    Fagny, Maud; Platig, John; Kuijjer, Marieke Lydia; Lin, Xihong; Quackenbush, John (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Background Genome-wide association studies (GWASes) have identified many noncoding germline single-nucleotide polymorphisms (SNPs) that are associated with an increased risk of developing cancer. However, how these SNPs ...
  • PUMA: PANDA Using MicroRNA Associations 
    Kuijjer, Marieke Lydia; Fagny, Maud; Marin, Alessandro; Quackenbush, John; Glass, Kimberly (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Abstract Motivation Conventional methods to analyze genomic data do not make use of the interplay between multiple factors, such as between microRNAs (miRNAs) and the messenger RNA (mRNA) ...
  • Sex Differences in Gene Expression and Regulatory Networks across 29 Human Tissues 
    Lopes-ramos, Camila; Chen, Cho-Yi; Kuijjer, Marieke Lydia; Paulson, Joseph N.; Sonawane, Abhijeet; Fagny, Maud; Platig, John; Glass, Kimberly; Quackenbush, John; DeMeo, Dawn L. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Sex differences manifest in many diseases and may drive sex-specific therapeutic responses. To understand the molecular basis of sex differences, we evaluated sex-biased gene regulation by constructing sample-specific gene ...