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  • Accurate microRNA annotation of animal genomes using trained covariance models of curated microRNA complements in MirMachine 
    Umu, Sinan Ugur; Paynter, Vanessa Molin; Trondsen, Håvard; Buschmann, Tilo; Rounge, Trine Ballestad; Peterson, Kevin J.; Fromm, Bastian (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    The annotation of microRNAs depends on the availability of transcriptomics data and expert knowledge. This has led to a gap between the availability of novel genomes and high-quality microRNA complements. Using >16,000 ...
  • Achieving objective response in treatment of non-resectable neuroendocrine tumors does not predict longer time to progression compared to achieving stable disease 
    Thiis-Evensen, Espen; Poole, Amalie C; Nguyen, Hong-Thien T; Sponheim, Jon (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Background There are several treatment modalities for unresectable neuroendocrine tumors. Traditionally, the aim of these treatments has been to reduce the tumor load; referred to as objective response (OR). Less emphasis ...
  • Activated dendritic cells and monocytes in HIV immunological nonresponders: HIV-induced interferon-inducible protein-10 correlates with low future CD4+ recovery 
    Stiksrud, Birgitte; Aass, Hans Christian Dalsbotten; Lorvik, Kristina Berg; Ueland, Thor; Trøseid, Marius; Dyrhol-Riise, Anne Ma (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    Objective: To explore monocyte and dendritic cell immune responses, and their association with future CD4+ gain in treated HIV patients with suboptimal CD4+ recovery. Design: A cross-sectional study of HIV-infected, ...
  • Active antibiotic discontinuation in suspected but not confirmed early‐onset neonatal sepsis—A quality improvement initiative 
    Dretvik, Thomas Bruvoll; Solevåg, Anne Lee; Finvåg, Andreas; Størdal, Eline Hasselgård; Størdal, Ketil; Klingenberg, Claus (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Aim To study whether a simple targeted intervention could reduce unwarranted antibiotic treatment in near‐term and term neonates with suspected, but not confirmed early‐onset sepsis. Methods A quality improvement ...
  • Adherence to Guidelines for Acute Rehabilitation in the Norwegian Trauma Plan. 
    Schäfer, Christoph; Moksnes, Håkon Øgreid; Rasmussen, Mari Storli; Hellstrøm, Torgeir; Søberg, Helene L.; Røise, Olav; Røe, Cecilie; K Frisvold, Shirin; Bartnes, Kristian; Næss, Pål Aksel; Gaarder, Aslaug Christine; Helseth, Eirik; Brunborg, Cathrine; Andelic, Nada; Anke, Audny Gabriele Wagner (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    Objective: To evaluate adherence to 3 central operational recommendations for acute rehabilitation in the Norwegian trauma plan.Methods: A prospective multi-centre study of 538 adults with moderate and severe trauma with ...
  • Adherence, Competence, and Alliance as Predictors of Long-term Outcomes of Cognitive Behavioral Therapy for Youth Anxiety Disorders 
    Bjaastad, Jon Fauskanger; Gjestad, Rolf; Fjermestad, Krister Westlye; Öst, Lars Gøran; Haugland, Bente Storm Mowatt; Kodal, Arne; Heiervang, Einar Røshol; Wergeland, Gro Janne Henningsen (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    Abstract The present study investigated therapist adherence, therapist competence, and patient-therapist alliance as predictors of long-term outcomes of cognitive behavioral therapy (CBT) for anxiety disorders in youth. ...
  • Adipose Tissue Characterization With Electrical Impedance Spectroscopy and Machine Learning 
    Dapsance, Florian; Hou, Jie; Dufour, Damien; Boccara, Charlotte; Briand, Nolwenn; Martinsen, Ørjan Grøttem (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    Biological tissues have variable passive electrical properties depending on their cellular constitution. Electrical impedance spectroscopy (EIS) is commonly used to monitor cell and tissue characteristics. By measuring the ...
  • Adjustment of spurious correlations in co-expression measurements from RNA-Sequencing data 
    Hsieh, Ping-Han; Lopes-Ramos, Camila Miranda; Zucknick, Manuela; Sandve, Geir Kjetil Ferkingstad; Glass, Kimberly; Kuijjer, Marieke (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    Abstract Motivation Gene co-expression measurements are widely used in computational biology to identify coordinated expression patterns across a group of samples. Coordinated expression ...
  • Advanced in developmental organic and inorganic nanomaterial: a review 
    Khalid, Khalisanni; Tan, Xuefei; Mohd Zaid, Hayyiratul Fatimah; Tao, Yang; Lye Chew, Chien; Chu, Dinh Toi; Lam, Man Kee; Ho, Yeek-Chia; Lim, Jun Wei; Chin Wei, Lai (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    With the unique properties such as high surface area to volume ratio, stability, inertness, ease of functionalization, as well as novel optical, electrical, and magnetic behaviors, nanomaterials have a wide range of ...
  • Aggressive Treatment of Patients with Metastatic Colorectal Cancer Increases Survival: A Scandinavian Single-Center Experience 
    Brudvik, Kristoffer Watten; Bains, Simer Jit; Seeberg, Lars Thomas; Labori, Knut Jørgen; Waage, Anne; Tasken, Kjetil; Aandahl, Einar Martin; Bjørnbeth, Bjørn Atle (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
    Background. We examined overall and disease-free survivals in a cohort of patients subjected to resection of liver metastasis from colorectal cancer (CRLM) in a 10-year period when new treatment strategies were implemented. ...
  • Akutt forgiftning ved rusrelatert bruk av benzodiazepiner 
    Andersson, Jon Andreas; Brekke, Mette; Vallersnes, Odd Martin (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    BAKGRUNN Benzodiazepiner brukes også som rusmidler. Dette kan være farlig, særlig ved blandingsrus. Vi beskriver akutte forgiftninger ved rusrelatert bruk av benzodiazepiner hos pasienter på Legevakten i Oslo. MATERIALE ...
  • Alcohol abstinence and drinking among African women: data from the World Health Surveys 
    Martinez, Priscilla; Røislien, Jo; Naidoo, Nirmala; Clausen, Thomas (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2011)
    Background Alcohol use is increasing among women in Africa, and comparable information about women's current alcohol use is needed to inform national and international health policies relevant to the entire ...
  • ALK inhibition activates LC3B-independent, protective autophagy in EML4-ALK positive lung cancer cells 
    Schläfli, Anna M.; Tokarchuk, Igor; Parejo, Sarah; Jutzi, Susanne; Berezowska, Sabina; Engedal, Nikolai; Tschan, Mario P. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    Abstract ALK inhibitors effectively target EML4-ALK positive non-small cell lung cancer, but their effects are hampered by treatment resistance. In the present study, we asked whether ALK inhibition affects autophagy, and ...
  • The Amino Acid Transporters of the Glutamate/GABA-Glutamine Cycle and Their Impact on Insulin and Glucagon Secretion 
    Jenstad, Monica; Chaudhry, Farrukh Abbas (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
    Intercellular communication is pivotal in optimizing and synchronizing cellular responses to keep homeostasis and to respond adequately to external stimuli. In the central nervous system (CNS), glutamatergic and GABAergic ...
  • An EST-based approach for identifying genes expressed in the intestine and gills of pre-smolt Atlantic salmon (Salmo salar) 
    Hagen-Larsen, Heidi; Laerdahl, Jon K; Panitz, Frank; Adzhubei, Alexei; Høyheim, Bjørn (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2005)
    Background The Atlantic salmon is an important aquaculture species and a very interesting species biologically, since it spawns in fresh water and develops through several stages before becoming a smolt, ...
  • An update on the progress of isolation, culture, storage, and clinical application of human bone marrow mesenchymal stem/stromal cells 
    Chu, Dinh Toi; Phuong, Thuy Nguyen Thi; Tien, Nguyen Le Bao; Tran, Dang Khoa; Thanh, Vo Van; Quang, Thuy Luu; Truong, Dang Tien; Pham, Van-Huy; Ngoc, Vo Truong Nhu; Chu-Dinh, Thien; Kushekhar, Kushi (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Bone marrow mesenchymal stem/stromal cells (BMSCs), which are known as multipotent cells, are widely used in the treatment of various diseases via their self-renewable, differentiation, and immunomodulatory properties. ...
  • The androgen receptor controls expression of the cancerassociated sTn antigen and cell adhesion through induction of ST6GalNAc1 in prostate cancer 
    Munkley, Jennifer; Oltean, Sebastian; Vodak, Daniel; Wilson, Brian T.; Livermore, Karen E.; Zhou, Yan; Star, Eleanor; Floros, Vasileios I.; Johannessen, Bjarne; Knight, Bridget; McCullagh, Paul; McGrath, John; Crundwell, Malcolm; Skotheim, Rolf Inge; Robson, Craig N.; Leung, Hing Y.; Harries, Lorna W.; Rajan, Prabhakar; Mills, Ian Geoffrey; Elliott, David J. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
    Patterns of glycosylation are important in cancer, but the molecular mechanisms that drive changes are often poorly understood. The androgen receptor drives prostate cancer (PCa) development and progression to lethal ...
  • Androgen receptor deregulation drives bromodomain-mediated chromatin alterations in prostate cancer 
    Urbanucci, Alfonso; Barfeld, Stefan Jörg; Kytölä, Ville; Itkonen, Harri; Coleman, Ilsa M.; Vodák, Daniel; Sjöblom, Liisa; Sheng, Xia; Minner, Sarah; Burdelski, Christoph; Kivinummi, Kati K.; Kohvakka, Annika; Kregel, Steven; Takhar, Mandeep; Alshalalfa, Mohammed; Davicioni, Elai; Erho, Nicholas; Lloyd, Paul; Karnes, R. Jeffrey; Ross, Ashley E.; Schaeffer, Edward M.; Vander Griend, Donald J; Knapp, Stefan; Corey, Eva; Feng, Felix Y.; Nelson, Peter S.; Saatcioglu, Fahri; Knudsen, Karen E.; Tammela, Teuvo L.J.; Sauter, Guido; Schlomm, Thorsten; Nykter, Matti; Visakorpi, Tapio; Mills, Ian Geoffrey (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    Global changes in chromatin accessibility may drive cancer progression by reprogramming transcription factor (TF) binding. In addition, histone acetylation readers such as bromodomain-containing protein 4 (BRD4) have been ...
  • Angular and linear speed cells in the parahippocampal circuits 
    Spalla, Davide; Treves, Alessandro; Boccara, Charlotte (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    Abstract An essential role of the hippocampal region is to integrate information to compute and update representations. How this transpires is highly debated. Many theories hinge on the integration of self-motion signals ...
  • Annotated Expressed Sequence Tags (ESTs) from pre-smolt Atlantic salmon (Salmo salar) in a searchable data resource 
    Adzhubei, Alexei A; Vlasova, Anna V; Hagen-Larsen, Heidi; Ruden, Torgeir A; Laerdahl, Jon K; Høyheim, Bjørn (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2007)
    Background To identify as many different transcripts/genes in the Atlantic salmon genome as possible, it is crucial to acquire good cDNA libraries from different tissues and developmental stages, their ...