Browsing Molekylærbiologi by Title
Now showing items 108-127 of 146
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(Master thesis / Masteroppgave, 2012)Previous studies indicate that central sensitization may be an underlying mechanism of hyperalgesia and development of persistent pain. However, some individuals may have a higher risk of long lasting pain than others, ...
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(Master thesis / Masteroppgave, 2010)Malignant peripheral nerve sheath tumour (MPNST) is a rare and highly aggressive malignancy with high frequency of both local recurrence and distant metastasis. About half of all cases arise in individuals with the hereditary ...
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PTM-crosstalk in c-Myb : Analysis of interdependence between posttranslational modifications in the negative regulatory domain of the oncoprotein c-Myb.Restricted Access (Master thesis / Masteroppgave, 2009)
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(Master thesis / Hovedoppgave, 2007)There is a fine balance between Ag presentation and by the destruction of Ag peptides. In a “Troybody” vaccine design it is of great importance that the introduced epitopes are properly excised from the Ab molecule. Specific ...
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(Master thesis / Masteroppgave, 2011)Gb3 (Gal α1-4, Gal β1-4, Glc β1-1, Ceramide) is a neutral glycosphingolipid specifically expressed in several human tissues, and is recognised as a receptor for Shiga toxins. Gb3 has been demonstrated to be upregulated in ...
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(Master thesis / Masteroppgave, 2005)Androgen ablation during the initial stages of prostate cancer causes regression of the tumor due to an increase in apoptosis and reduced cellular proliferation. However, some prostate cancer cells survive in the androgen ...
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(Master thesis / Masteroppgave, 2008)The crucian carp (Carassius carassius) inhabits lakes and ponds in Northern Europe, where it is able to survive anoxia that often occurs for months during the long winter. Several physiological adaptations, including the ...
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(Master thesis / Masteroppgave, 2011)In addition to providing morphological support, the actin cytoskeleton is involved in cell motility, endocytosis and intracellular transport. Cytoskeletal interaction with the membrane is an essential part of these processes ...
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(Master thesis / Masteroppgave, 2008)Animals store most excess energy as fat in specialized cells called adipocytes which form the major part of adipose tissue. Since obesity, which has reached epidemic proportions in the last decades, is the result of excess ...
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The Role of SNX8 in Retrograde Transport of Shiga Toxin : SNX8 facilitated transport of Shiga toxin is regulated by PKCdelta and p38alfaRestricted Access (Master thesis / Masteroppgave, 2010)Sorting nexin 8 (SNX8) belongs to the sorting nexin protein family. Members of this family are known to be involved in endocytosis and endosomal sorting. It was recently reported that SNX8 regulates retrograde transport ...
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(Master thesis / Masteroppgave, 2012)Colorectal cancer (CRC) is a common type of cancer, and at present the TNM staging system is the only tool in routine clinical use for predicting patient outcome and making treatment decisions. Nuclear expression of the ...
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(Master thesis / Masteroppgave, 2006)Sequence-specific double-stranded small interfering RNAs (siRNAs) may effectively silence gene expression via a mechanism called RNA interference (RNAi). The focus of this study was mainly identification of active siRNA ...
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(Master thesis / Masteroppgave, 2005)Abstract The intention of this study was to identify and characterize signal pathways of the mesenchymal stem cell line hMSC-TERT which are being influenced by different mediators of inflammation. The purpose was also to ...
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(Master thesis / Masteroppgave, 2007)Colorectal cancer is one of the most common cancer types, and a leading cause of cancer-related deaths. Cases can be divided into two main molecular phenotypes: those with chromosomal instability (CIN) and those with ...
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Soluble and membrane bound peptide-MHC class II complexes as ligands for a specific T-cell receptor (Master thesis / Masteroppgave, 2007)Abstracts 1. Production of soluble peptide-MHC class II-Ig fusion proteins The aim of the study is to construct soluble variants of the murine MHC class II molecule I-Ed in complex with two tumor-specific peptides. ...
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(Master thesis / Masteroppgave, 2008)Epitelcellelinjen ”Madin-Darby canine kidney (MDCK)” er en velstudert polarisert cellelinje som danner tette cellelag med separate apikale og basolaterale membrandoméner. Proteoglykaner sorteres til både den apikale og den ...
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(Master thesis / Masteroppgave, 2011)
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(Master thesis / Masteroppgave, 2010)Fatty-acid amide hydrolase (FAAH) is an enzyme that metabolizes several endocannabinoids and fatty acid amides. A functional variant of the gene encoding FAAH, which reduces the enzymatic activity, has been associated with ...
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(Master thesis / Masteroppgave, 2010)Six transmembrane protein of prostate 2 (STAMP2) is a six transmembrane domain protein in the STAMP/STEAP family. It is primarily found in the prostate, visceral adipose tissue, and bone marrow, and is overexpressed in ...
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(Master thesis / Prosjektoppgave, 2012)Abstract Endonuclease V (EndoV) is highly conserved from prokaryotes to eukaryotes. Endonuclease V in E. coli functions in repair of DNA damages caused by deamination of adenine and guanine in particular. E. coli EndoV ...