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(Master thesis / Masteroppgave, 2006)Cancer of the large bowel may be looked upon as a model of stepwise tumor development, as it has morphological distinct benign and malignant stages paralleling a preferential order of genetic and epigenetic aberrations. ...
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(Master thesis / Masteroppgave, 2006)SUMMARY Blood coagulation may lead to venous thromboembolism (VTE). Tissue factor pathway inhibitor (TFPI) is an important inhibitor of blood coagulation, however, the clinical significance or frequency of TFPI deficiency ...
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(Master thesis / Masteroppgave, 2006)Cystic fibrosis (CF) is an inherited, recessive disease that primarily affects the pancreas of the digestive system and the lungs of the respiratory system. The disease is caused by mutations in the gene encoding the CFTR ...
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(Master thesis / Masteroppgave, 2006)Autoimmune diseases are the drawback of having a potent immune defence. Type 1 diabetes and myasthenia gravis are examples of such diseases, where disease development is both complex and multifactorial. In general, both ...
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(Master thesis / Masteroppgave, 2006)Denne mastergradsoppgaven beskriver etablering av en eksperimentell plattform for identifisering av nødvendige og tilstrekkelige komponenter i teratocarcinoma NCCIT celleekstrakt for reprogrammering av 293T celler. ...
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(Master thesis / Masteroppgave, 2006)This thesis reports an in vitro reprogramming approach with pig thymocyte extracts to induce expression of two lymphoid-specific recombination activating enzyme genes, RAG1 and RAG2, in human kidney epithelial 293T cells. ...
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(Master thesis / Masteroppgave, 2007)Identifikasjonen av proteinet hNCU-G1 er basert på interaksjonen med hCRBP1-promoterens FP1-element (+66-+99), som ble gjort ved EMSA-studier. Videre studier avslørte at hNCU-G1 kunne fungere som en transkripsjonsfaktor ...
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(Master thesis / Masteroppgave, 2007)Human bone marrow multipotent mesenchymal stromal cells (hBM-MSC) represent an appealing source of adult stem cells for cell therapy and tissue engineering. Since hBM-MSC are present at low frequency in the bone marrow, ...
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(Master thesis / Masteroppgave, 2007)Prostate cancer is the most common non-skin cancer and the third leading cause of cancer death in men in developed countries. No effective cure has yet been found to treat the hormone refractory state of PCa. In addition ...
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(Master thesis / Masteroppgave, 2007)In the 5`UTR of transcripts of the Chlamydomonas chloroplast gene rbcL secondary structures in the shape of two stem loops, one large and one small, have been identified. The large stem loop has been found to mediate folding ...
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(Master thesis / Masteroppgave, 2007)Sammendrag hNCU-G1 ble først identifisert som et protein som interagerte med FP1 i hCRBP-promoteren. Videre studier viste at hNCU-G1 var i stand til å fungere som transkripsjonsfaktor fra denne promoteren. Strukturelle ...
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(Master thesis / Masteroppgave, 2007)Colorectal cancer is one of the most common cancer types, and a leading cause of cancer-related deaths. Cases can be divided into two main molecular phenotypes: those with chromosomal instability (CIN) and those with ...
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(Master thesis / Masteroppgave, 2007)Amplification of several regions of chromosome 8q is frequently detected in breast tumors, and several genes located on this chromosome arm show increased expression in the tumors. One of these genes encodes ã-glutamyl ...
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(Master thesis / Masteroppgave, 2007)The E. coli AlkB protein reverses methylation damage from DNA and RNA by oxidative demethylation, a reaction dependent on Fe(II) and 2-oxoglutarate. Based on sequence similarity, eight human AlkB homologues, denoted hABH1-8, ...
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(Master thesis / Masteroppgave, 2007)Hematopoiesis is the process by which the hematopoietic stem cells differentiate into a variety of specialized cells (mature blood cells). The development of the definitive hematopoietic cell lineages is regulated by a ...
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Soluble and membrane bound peptide-MHC class II complexes as ligands for a specific T-cell receptor (Master thesis / Masteroppgave, 2007)Abstracts 1. Production of soluble peptide-MHC class II-Ig fusion proteins The aim of the study is to construct soluble variants of the murine MHC class II molecule I-Ed in complex with two tumor-specific peptides. ...
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(Master thesis / Masteroppgave, 2007)Abstract. The c-Myb transcription factor plays a central role in regulation of growth, differentiation and survival of hematopoietic cells. Despite being studied for many years, the understanding of how c-Myb functions ...
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(Master thesis / Masteroppgave, 2007)Most vertebrates depend on an uninterrupted supply of oxygen to maintain the energy production. Some species, like the crucian carp (Carassius carassius) can survive hypoxia for an extended period. This fish is an expert ...
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(Master thesis / Masteroppgave, 2007)The gene rbcL in the Chlamydomonas chloroplast codes for a mRNA of about 1.6 kb including a 5`UnTranslated Region (5`UTR) of 92 bp.The beginning of the 5`UTR has two stem-loops as part of its secondary structure. A ...
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(Master thesis / Masteroppgave, 2007)hNCU-G1 ble for første gang identifisert som transkripsjonsfaktor for humant CRBP1. Det baserte seg på EMSA forsøk der man så at det interagerte med FP1 (+66, +99) element i denne promotoren. hNCU-G1 har fire LXXLL motiver ...