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Now showing items 1-100 of 2794
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Background
National guidelines emphasize healthy eating to promote wellbeing and prevention of non-communicable diseases. The perceived healthiness of food is determined by many factors affecting food ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
Atlases of the rat brain are widely used as reference for orientation, planning of experiments, and as tools for assigning location to experimental data. Improved quality and use of magnetic resonance imaging (MRI) and ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Nutrigenetic research examines the effects of inter-individual differences in genotype on responses to nutrients and other food components, in the context of health and of nutrient requirements. A practical application of ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Background
Beyond survival of nowadays >80%, modern childhood cancer treatment strives to preserve long-term health and quality of life. However, the majority of today’s survivors suffer from short- and ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
To validate estimated intakes of carotenoid-rich foods from a web-based food recall (WebFR) using carotenoids in blood as an objective reference method.
Cross-sectional validation study using carotenoids in plasma to ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
Background
A wide range of diseases show some degree of clustering in families; family history is therefore an important aspect for clinicians when making risk predictions. Familial aggregation is often ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Background
The phenotypic stability of mixed connective tissue disease (MCTD) is not clear, and knowledge about disease activity and remission is scarce. We aimed to establish the occurrence of evolution ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Long-term impact of intrauterine fetal death on quality of life and depression: a case–control study
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2012)
Background
Intrauterine fetal death (IUFD) is a serious incidence that has been shown to impact mothers’ psychological well-being in the short-term. Long-term quality of life (QOL) and depression after IUFD ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
Background: Signalling proteins often contain several well defined and conserved protein domains. Structural analyses of such domains by nuclear magnetic spectroscopy or X-ray crystallography may greatly inform the function ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
Objectives: (1) To investigate the experiences of women with a previous stillbirth and their appraisal of the care they received at the hospital. (2) To assess the long-term level of post-traumatic stress symptoms (PTSS) ...
(Doctoral thesis / Doktoravhandling, 2010)
Over the past decades many western countries have witnessed an epidemic rise in obesity, insulin resistance and type 2 diabetes. There clearly is a link between increased fat storage and decreased insulin sensitivity leading ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
Background
Diet has a great impact on the risk of developing features of metabolic syndrome (MetS), type 2 diabetes mellitus (T2DM), and cardiovascular diseases (CVD). We evaluated whether a long-term ...
(Master thesis / Masteroppgave, 2009)
Regular physical activity has beneficial effects on health. The relations between exercise and health are not fully understood. Myokines are secretory peptides of skeletal muscle origin with auto-, para- or endocrine ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
Background Recent studies suggest that lactation has long-term effects on risk for cardiovascular disease in women, but the effects on cardiovascular mortality are less well known. Method In a Norwegian population-based ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
Objective: Examine responses given to questions addressing whether pregnancy had caused women with nausea and vomiting (NVP) or symptom-free (SF) to alter their food habits in the first trimester in order to better understand ...
(Doctoral thesis / Doktoravhandling, 2018)
På samme måte som søppel dannes fra vårt daglige forbruk, produserer cellene i kroppen vår avfallsprodukter som transporteres til cellens resykleringsstasjon (lysosomet), hvor det brytes ned og gjenvinnes. Dette skjer via ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
The purpose of this study was to validate estimated energy intake from a web-based food recall, designed for children and adolescents. We directly compared energy intake to estimates of total energy expenditure, calculated ...
(Doctoral thesis / Doktoravhandling, 2008)
I fire vitenskaplige arbeider, har vi studert data fra det Norske mammografi programmet (brystkreft screening programmet), med moderne statistiske metoder og kraftige datamaskiner. I det første arbeidet ser vi at risikoen ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
Intercellular communication is pivotal in optimizing and synchronizing cellular responses to keep homeostasis and to respond adequately to external stimuli. In the central nervous system (CNS), glutamatergic and GABAergic ...
(Doctoral thesis / Doktoravhandling, 2007)
Chronic fatigue syndrome (CFS) is a disabling disease with unknown pathophysiology, but recent evidence suggests autonomic dysfunction. We have therefore explored cardiovascular and thermoregulatory autonomic responses. ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
Background
More than 14 % of Ugandan children are orphaned and many live in children’s homes. Ugandan authorities have targeted adolescent girls as a priority group for nutrition interventions as safeguarding ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
Background
Fish consumption may prevent or improve metabolic health. The aim of this study was to identify associations between fish consumption, both fatty and lean, and metabolic syndrome and its ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
Background
Early adulthood is a period associated with poor diet and rapid weight gain. This is also an age of transition, including environmental, social and lifestyle changes which may be associated with ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Background
Policy frameworks focusing on policy implementation may vary in terms of their scope, included constructs, relationships between the constructs, and context factors. Although multiple policy ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
Background
Doctor –certified sick leave is prevalent in the health and social sector. We examined whether the higher risk of doctor-certified sick leave in women in health and social occupations compared ...
(Doctoral thesis / Doktoravhandling, 2016)
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
Background
Fish consumption may have a role in reducing the prevalence of metabolic syndrome (MetS). The aim of this study was to identify associations between fish consumption and MetS and its components, ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
Background
Understanding the determinants associated with prediabetes and type 2 diabetes in coronary patients may help to individualize treatment and modelling interventions. We sought to identify ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Background
The endovascular treatment procedure in tandem occlusions (TO) is complex compared to single occlusion (SO) and optimal management remains uncertain. The aim of this study was to identify clinical ...
(Doctoral thesis / Doktoravhandling, 2016)
GABA and glutamate transporter proteins are important in relation to epilepsy because they represent the mechanisms that keep the extracellular concentrations of GABA and dicarboxylic amino acids low. GABA and glutamate ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
Background
Multi-item rating scales for depression informs about the level of depression, but does not allow individuals to state by self-evaluation whether they feel depressed or not. The insider perspective ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
The comet assay has developed over the past 30 years and today, a variety of different DNA lesions and DNA repair can be measured by different versions of the assay (Collins, 2004). In the final step of the method, an image ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2005)
RNA interference (RNAi) has become an invaluable tool for functional genomics. A critical use of this tool depends on an understanding of the factors that determine the specificity and activity of the active agent, small ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
Patients’ knowledge about psoriasis and its treatment has been randomly studied previously. The aim of the study is to investigate patients’ knowledge about psoriasis in relation to undergoing patient education in the ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
Background Fruit and vegetable intake has been found to reduce the risk of cardiovascular disease, certain types of cancer and diabetes mellitus. It is possible that antioxidants play a large part in this protective effect. ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
Genome-wide sequencing technologies enable investigations of the structural properties of the genome in various spatial dimensions. Here, we review computational techniques developed to model the three-dimensional genome ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Background
Previous studies suggest that persistent exposure to social stress in mammals may be associated with multiple physiological effects. Here, we examine the effects of social stress in rats, i.e. repeated social ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
α2-adrenoceptor-activation lowers central sympathetic output, peripheral, vesicular norepinephrine release, epinephrine secretion and modulates vascular tension. We previously demonstrated that α2-adrenoceptor-mediated ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
α2-Adrenoceptors lower central sympathetic output and peripheral catecholamine release, and thus may prevent sympathetic hyperactivity and hypertension. α2AR also influence vascular tension. These α2AR are malfunctioning ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
Peripheral norepinephrine release is facilitated by presynaptic β-adrenoceptors (AR), believed to involve the β2-subtype exclusively. However, β1-selective blockers are the most commonly used β-blockers in hypertension. ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2011)
Sympathetic hyperactivity and parasympathetic insufficiency characterize blood pressure (BP) control in genetic hypertension. This shift is difficult to investigate in anesthetized rats. Here we present a pharmacological ...
(Doctoral thesis / Doktoravhandling, 2015)
The thesis describes the electrical activity in nerve cells (motoneurons) that control the deep back muscles in humans. The experiments were conducted using thin wire electrodes that were implanted deep in the spinal muscles ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
Biomarkers of nutrient intake or nutrient status are important objective measures of foods/nutrients as one of the most important environmental factors people are exposed to. It is very difficult to obtain accurate data ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
Background Few studies have focused on fatigue in myasthenia gravis (MG), and fatigue in relation to the autonomic system has never been systematically explored in these patients. The study aimed to document the prevalence ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
The system N transporter SN1 (also known as SNAT3) is enriched on perisynaptic astroglial cell membranes. SN1 mediates electroneutral and bidirectional glutamine transport, and regulates the intracellular as well as the ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
Knowledge of illness perception may aid the identification of groups of patients with a higher risk of coping
poorly with the demands of their illness. This study aims to investigate associations between illness perception, ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
Here, the influence of β3-adrenoceptors on catecholamine release in normotensive and spontaneously hypertensive rats was analyzed. Blood pressure was recorded through a femoral artery catheter, and cardiac output by ascending ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
Background: Cobalamin and folate are essential micronutrients and are important in DNA and RNA synthesis, cell proliferation, growth, hematopoiesis, and cognitive function. However, data on cobalamin and folate status are ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2016)
Background Changes in electroencephalography (EEG) voltage range are used to monitor the depth of anaesthesia, as well as predict outcome after hypoxia-ischaemia in neonates. Xenon is being investigated as a potential ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
Neonatal hypoxic‐ischemic encephalopathy (HIE) is associated with alterations in cerebral blood flow (CBF) as a result of perinatal asphyxia. The extent to which CBF changes contribute to injury, and whether treatments ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
Objective In women, the risk for non-communicable diseases increases after menopause. We aimed to identify major dietary patterns and study their associations with nutrient intake, sociodemographic factors and risk factors ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
Background: Compared to food patterns, nutrient patterns have been rarely used particularly at international level. We studied, in the context of a multi-center study with heterogeneous data, the methodological challenges ...
(Doctoral thesis / Doktoravhandling, 2017)
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Background
Lack of Hepatitis C virus (HCV) incidence data in (Norwegian) high-risk groups impedes the ability to make informed decisions on prevention measures. Thus we rely on modelling to estimate the ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
In the dairy breeding industry, prediction of bull fertility in artificial insemination (AI) is important for efficient and economically sustainable production. However, it is challenging to identify bulls with superior ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2014)
Blood pressure is a critical determinant of cardiovascular morbidity and mortality. It is affected by environmental factors, but has a strong heritable component. Despite recent large genome-wide association studies, few ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
The three-dimensional (3D) structure of the genome is important for orchestration of gene expression and cell differentiation. While mapping genomes in 3D has for a long time been elusive, recent adaptations of high-throughput ...
(Doctoral thesis / Doktoravhandling, 2020)
The three-dimensional (3D) organization of chromatin in the mammalian cell nucleus plays an important role in the regulation of gene expression. In her Ph.D. thesis, Anna Frida Forsberg has investigated the impact of ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
Objective: Neurocognitive impairment is commonly reported at onset of psychotic disorders. However, the long-term neurocognitive course remains largely uninvestigated in first episode psychosis (FEP) and the relationship ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2007)
Background
This is a six-year prospective follow-up of a former cross sectional study of suicide attempters in a sample of treatment-seeking substance-dependent patients. The aims were to explore the frequency ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2007)
Background
Communication training builds on the assumption that understanding of the concepts related to professional communication facilitates the training. We know little about whether students' knowledge ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
Background
Self-evaluations of mental health problems may be a useful complement to diagnostic assessment, but are less frequently used. This study investigated the prevalence of self-evaluated current and ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Background
There is a lack of comprehensive patient-datasets regarding prevalence of severe hypertriglyceridemia (sHTG; triglycerides ≥10 mmol/L), frequency of co-morbidities, gene mutations, and gene ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2009)
Vaccines using dendritic cells (DCs) harboring leukemic antigens to stimulate T cells is a possible treatment of acute myeloid leukemia (AML). Limitations of breaking tolerance to leukemic cells and lack of specific ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
Aquaporin-4 (AQP4) water channels are concentrated in astrocytic endfoot membranes at the brain–blood and brain–cerebrospinal fluid interfaces. The mechanisms underpinning the polarized distribution of AQP4 are poorly ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2012)
Rheumatoid arthritis (RA) is a long-term disease that leads to inflammation of the joints and surrounding tissues. Natural killer(NK) cells are an important part of the innate immune system and are responsible for the first ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
Crucian carp are unusual among vertebrates in surviving extended periods in the complete absence of molecular oxygen. During this time cardiac output is maintained though these mechanisms are not well understood. Using a ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
Background: There is a need for valid and comprehensive measures of parental influence on children’s energy balance-related behaviours (EBRB). Such measures should be based on a theoretical framework, acknowledging the ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2011)
Background: Polychlorinated biphenyls (PCBs) are a class of organic compounds that bioaccumulate due to their chemical stability and lipophilic properties. Humans are prenatally exposed via trans-placental transfer, through ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
The T cell specific adapter protein (TSAd) is expressed in activated T cells and NK cells. While TSAd is beginning to emerge as a critical regulator of Lck and Itk activity in T cells, its role in NK cells has not yet been ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
Nondirective meditation techniques are practiced with a relaxed focus of attention that permits spontaneously occurring thoughts, images, sensations, memories, and emotions to emerge and pass freely, without any expectation ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2012)
The process of radiationless energy transfer from a chromophore in an excited electronic state (the donor ) to another chromophore (an acceptor ), in which the energy released by the donor effects an electronic transition, ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
The ALKBH family of Fe(II) and 2-oxoglutarate dependent oxygenases comprises enzymes that display sequence homology to AlkB from E. coli, a DNA repair enzyme that uses an oxidative mechanism to dealkylate methyl and etheno ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
Background
Using high-dimensional penalized regression we studied genome-wide DNA-methylation in bone biopsies of 80 postmenopausal women in relation to their bone mineral density (BMD). The women showed ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
Objective To compare cognitive function in adolescents with chronic fatigue with cognitive function in healthy controls (HC).
Study design Cross-sectional study.
Setting Paediatric department at Oslo University Hospital, ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
In the comet assay single cells are analyzed with respect to their level of DNA damage. Discrimination of the individual cell or cell type based on DNA content, with concomitant scoring of the DNA damage, is useful since ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
Lipids through regulation of chronic inflammation play key roles in the development of various diseases. Here, we report that a mixed population of human primary monocytes migrated towards LPC, as well as oxidized linoleic ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
Background
Young patients with acute poisoning by substances of abuse have increased mortality rates in the long term. In Oslo, Norway, most of these patients are treated at the Oslo Accident and Emergency ...
(Doctoral thesis / Doktoravhandling, 2018)
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
Objective
Earlier studies documenting the effect of candidate genes on recovery have seldom taken into consideration the impact of emotional distress. Thus, we aimed to assess the modifying effect of emotional ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2012)
To explore contemporary (from 1990) utilization and practice of electroconvulsive therapy (ECT) worldwide. Systematic search (limited to studies published 1990 and after) was undertaken in the databases Medline, Embase, ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
Lifestyle factors are responsible for a considerable portion of cancer incidence worldwide, but credible estimates from the World Health Organization and the International Agency for Research on Cancer (IARC) suggest that ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
Objective
We have previously found that 9% of patients treated for acute poisoning by substances of abuse in a primary care emergency outpatient setting presented with a new poisoning within a week. We now ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2012)
Dietary fat is normally in TAG form, but diacylglycerol (DAG) is a natural component of edible oils. Studies have shown that consumption of DAG results in metabolic characteristics that are distinct from those of TAG, which ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
BACKGROUND: The UP4FUN intervention is a family-involved school-based intervention aiming at reducing and breaking up sitting time at home (with special emphasis on screen time), and breaking up sitting time in school among ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
Monocytes play multiple roles in the immune system, and are active in both acute and chronic diseases. Patients exposed to bacterial infections depend on monocytes in defense reactions, but excessive immune reactions may ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
Background
Several studies have documented the variety of post-stroke psychosocial challenges, which are complex, multifaceted, and affect a patient’s rehabilitation and recovery. Due to the consequences ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
Background
Europe has a growing population of ethnic minority groups whose dietary behaviours are potentially of public health concern. To promote healthier diets, the factors driving dietary behaviours ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
Background
The existence of socioeconomic differences in dietary behaviors is well documented. However, studies exploring the mechanisms behind these differences among adolescents using comprehensive and ...
(Journal article / Tidsskriftartikkel / SubmittedVersion, 2015)
We recently characterized physiologically a pontine reticulospinal (pRS) projection in the neonatal mouse that mediates synaptic effects on spinal motoneurons via parallel uncrossed and crossed pathways (Sivertsen et al. ...
(Doctoral thesis / Doktoravhandling, 2016)
It is widely recognized that diet has an important effect on our health. A healthy and varied diet has the potential to reduce the risk of a number of non-communicable diseases. The traditional approach in nutrition ...
(Journal article / Tidsskriftartikkel / PublishedVersion, 2017)
Distinct DNA methylation profiles in bone and blood of osteoporotic and healthy postmenopausal women
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
DNA methylation affects expression of associated genes and may contribute to the missing genetic effects from genome-wide association studies of osteoporosis. To improve insight into the mechanisms of postmenopausal ...
Role of LSDP5 i diet induced obese and insulin resistant mice Restricted Access
(Master thesis / Masteroppgave, 2008)
(Master thesis / Masteroppgave, 2012)
(Doctoral thesis / Doktoravhandling, 2008)
Signalmolekylene i hjernen kan enten stimulere eller hemme nabocellene. Det viktigste stimulerende signalmolekylet er glutamat. Holten og medarbeidere legger i denne avhandlingen fram data som bekrefter at også aspartat ...