Browsing Institutt for molekylær biovitenskap by Author "Løset, Geir Å"

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  • Periplasmic expression of soluble single chain T cell receptors is rescued by the chaperone FkpA 
    Gunnarsen, Kristin S; Lunde, Elin; Kristiansen, Per E; Bogen, Bjarne; Sandlie, Inger; Løset, Geir Å (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2010)
    Background Efficient expression systems exist for antibody (Ab) molecules, which allow for characterization of large numbers of individual Ab variants. In contrast, such expression systems have been lacking ...
  • Stabilizing mutations increase secretion of functional soluble TCR-Ig fusion proteins 
    Lunde, Elin; Løset, Geir Å; Bogen, Bjarne; Sandlie, Inger (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2010)
    Background Whereas T cell receptors (TCRs) detect peptide/major histocompatibility complexes (pMHCs) with exquisite specificity, there are challenges regarding their expression and use as soluble detection ...