Browsing Institutt for molekylær biovitenskap by Title
Now showing items 50-69 of 121
-
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2009)FcγRIIA is a key activating receptor linking immune complex formation with cellular effector functions. FcγRIIA has 93% identity with an inhibitory receptor, FcγRIIB, which negatively regulates FcγRIIA. FcγRIIA is important ...
-
(Master thesis / Masteroppgave, 2005)Abstract Vascular endothelial cells contain typical, elongated vesicles called Weibel-Palade bodies (WPBs), which serve as a storage compartment for biologically active factors involved in hemostasis and inflammation. ...
-
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2011)Background Surface proteins are a key to a deeper understanding of the behaviour of Gram-positive bacteria interacting with the human gastro-intestinal tract. Such proteins contribute to cell wall synthesis ...
-
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2010)Background The HMGA2 gene, coding for an architectural transcription factor involved in mesenchymal embryogenesis, is frequently deranged by translocation and/or amplification in mesenchymal tumours, generally ...
-
(Master thesis / Masteroppgave, 2005)Abstract Increased pain response following injury is an important step in the process of protecting the injured site from further damage. However, pain can often be a more serious problem than the injury or disease process ...
-
(Master thesis / Hovedoppgave, 2004)Fibroblast growth factors and the four related high-affinity, tyrosine kinase fibroblast growth factor receptors are involved in the regulation of many key cellular responses in developmental and physiological processes. ...
-
(Master thesis / Hovedoppgave, 2005)In this study we have investigated by means of electron microscopy the uptake of the fragment crystallisable gamma receptor (FcãR) and its ligands (aggregated immunoglobulin G (AgIgG)) in J774 cells, a mouse macrophage ...
-
(Master thesis / Masteroppgave, 2012)The BEACH domain is common for a protein family that has expanded through eukaryotic evolution and contains eight human proteins. These proteins are generally very large and at their C-terminal ends contain a conserved set ...
-
(Doctoral thesis / Doktoravhandling, 2012)
-
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2008)Background Interaction data for a given protein may be spread across multiple databases. We set out to create a unifying index that would facilitate searching for these data and that would group together ...
-
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2011)Background The iRefIndex addresses the need to consolidate protein interaction data into a single uniform data resource. iRefR provides the user with access to this data source from an R environment. ...
-
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2011)Background The iRefIndex consolidates protein interaction data from ten databases in a rigorous manner using sequence-based hash keys. Working with consolidated interaction data comes with distinct challenges: ...
-
(Master thesis / Hovedoppgave, 2005)Genet som koder for chaperoninet GroESL1 i C. aurantiacus ble isolert fra et genomisk bibliotek av bakterien. Genet som koder for GroESL2 var tidligere isolert fra det samme biblioteket (Vanberg, Hovedfagsoppgave UiO, 2001) ...
-
(Master thesis / Hovedoppgave, 2005)Chaperoninene GroEL og GroES er en gruppe molekylære chaperoner som hittil er funnet i alle bakterier. Genene som koder for chaperoniner er vanligvis organisert i operoner på genomet. Den moderat termofile grønne glidende ...
-
(Master thesis / Hovedoppgave, 2005)Det humane genet WWOX har blitt identifisert av flere uavhengige forskningsgrupper i forbindelse med studier av strukturelle abnormaliteter av kromosom 16q i ulike krefttyper. Dette genet er lokalisert innenfor kromosom ...
-
(Master thesis / Hovedoppgave, 2004)In order to assess the biological role of the flap endonuclease 1 (Fen1), RNA interference (RNAi) was chosen as a method for FEN1 down-regulation in this study. Knock down of FEN1 was achieved both in stable transfected ...
-
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2011)Aldehyde dehydrogenase (ALDH) has recently been shown to be a marker of cancer stem-like cells (CSCs) across tumour types. The primary goals of this study were to investigate whether ALDH is expressed in liposarcomas, and ...
-
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2004)Background Microarray-based comparative genomic hybridisation (array CGH) is a technique by which variation in relative copy numbers between two genomes can be analysed by competitive hybridisation to DNA ...
-
(Master thesis / Hovedoppgave, 2004)Neurofibromatosis type 1 (NF1) is one of the most common autosomal dominant inherited disorders, and carriers are at greatly increased risk of developing malignant peripheral nerve sheath tumours (MPNST). The NF1 patients ...
-
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2005)Background Amplification of the q21-q23 region on chromosome 1 is frequently found in sarcomas and a variety of other solid tumours. Previous analyses of sarcomas have indicated the presence of at least ...