dc.date.accessioned | 2024-05-07T09:11:31Z | |
dc.date.available | 2024-05-07T09:11:31Z | |
dc.date.created | 2023-04-24T11:46:04Z | |
dc.date.issued | 2023 | |
dc.identifier.citation | Aastveit, Marthe Elisabeth Cunen, Celine Marie Løken Hjort, Nils Lid . A new framework for semi-Markovian parametric multi-state models with interval censoring. Statistical Methods in Medical Research. 2023, 32(6), 1053-1246 | |
dc.identifier.uri | http://hdl.handle.net/10852/110744 | |
dc.description.abstract | There are few computational and methodological tools available for the analysis of general multi-state models with interval censoring. Here, we propose a general framework for parametric inference with interval censored multi-state data. Our framework can accommodate any parametric model for the transition times, and covariates may be included in various ways. We present a general method for constructing the likelihood, which we have implemented in a ready-to-use R package, smms, available on GitHub. The R package also computes the required high-dimensional integrals in an efficient manner. Further, we explore connections between our modelling framework and existing approaches: our models fall under the class of semi-Markovian multi-state models, but with a different, and sparser parameterisation than what is often seen. We illustrate our framework through a dataset monitoring heart transplant patients. Finally, we investigate the effect of some forms of misspecification of the model assumptions through simulations. | |
dc.description.abstract | A new framework for semi-Markovian parametric multi-state models with interval censoring | |
dc.language | EN | |
dc.title | A new framework for semi-Markovian parametric multi-state models with interval censoring | |
dc.title.alternative | ENEngelskEnglishA new framework for semi-Markovian parametric multi-state models with interval censoring | |
dc.type | Journal article | |
dc.creator.author | Aastveit, Marthe Elisabeth | |
dc.creator.author | Cunen, Celine Marie Løken | |
dc.creator.author | Hjort, Nils Lid | |
cristin.unitcode | 185,15,13,25 | |
cristin.unitname | Statistikk og Data Science | |
cristin.ispublished | true | |
cristin.qualitycode | 2 | |
dc.identifier.cristin | 2142833 | |
dc.identifier.bibliographiccitation | info:ofi/fmt:kev:mtx:ctx&ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Statistical Methods in Medical Research&rft.volume=32&rft.spage=1053&rft.date=2023 | |
dc.identifier.jtitle | Statistical Methods in Medical Research | |
dc.identifier.volume | 32 | |
dc.identifier.issue | 6 | |
dc.identifier.startpage | 1100 | |
dc.identifier.endpage | 1123 | |
dc.identifier.doi | https://doi.org/10.1177/09622802231160550 | |
dc.type.document | Tidsskriftartikkel | |
dc.type.peerreviewed | Peer reviewed | |
dc.source.issn | 0962-2802 | |
dc.type.version | AcceptedVersion | |