Hide metadata

Narcolepsy risk loci outline role of T cell autoimmunity and infectious triggers in narcolepsy

dc.date.accessioned2024-02-20T18:12:33Z
dc.date.available2024-02-20T18:12:33Z
dc.date.created2023-08-15T10:36:12Z
dc.date.issued2023
dc.identifier.citationOllila, Hanna M. Sharon, Eilon Lin, Ling Sinnott-Armstrong, Nasa Ambati, Aditya Yogeshwar, Selina M. Hillary, Ryan P. Jolanki, Otto Faraco, Juliette Einen, Mali Luo, Guo Zhang, Jing Han, Fang Yan, Han Dong, Xiao Song Li, Jing Zhang, Jun Hong, Seung-Chul Kim, Tae Won Dauvilliers, Yves Barateau, Lucie Lammers, Gert Jan Fronczek, Rolf Mayer, Geert Santamaria, Joan Arnulf, Isabelle Knudsen, Stine Bredahl, May Kristin Lyamouri Thorsby, Per Medbøe Plazzi, Giuseppe Pizza, Fabio Moresco, Monica Crowe, Catherine Van den Eeden, Stephen K. Lecendreux, Michel Bourgin, Patrice Kanbayashi, Takashi Martínez-Orozco, Francisco J. Peraita-Adrados, Rosa Benetó, Antonio Montplaisir, Jacques Desautels, Alex Huang, Yu-Shu Als, Thomas Damm Ziemann, Adam Abbasi, Ali Lehtonen, Anne Lertratanakul, Apinya Riley-Gillis, Bridget Rahimov, Fedik Jacob, Howard Waring, Jeffrey Liu, Mengzhen Smaoui, Nizar Popovic, Relja Platt, Adam Matakidou, Athena Challis, Benjamin Paul, Dirk Lassi, Glenda Tachmazidou, Ioanna Hakanen, Antti Schleutker, Johanna Pitkänen, Nina Terho, Perttu Virolainen, Petri Mannermaa, Arto Kosma, Veli-Matti Chen, Chia-Yen Runz, Heiko John, Sally Lahdenperä, Sanni Loomis, Stephanie Eaton, Susan Okafo, George Salminen-Mankonen, Heli Jung, Marc Lawless, Nathan Ding, Zhihao Maranville, Joseph Hochfeld, Marla Plenge, Robert Biswas, Shameek Kanai, Masahiro Maasha, Mutaamba Zhou, Wei Tuovila, Outi Pakkanen, Raimo Laukkanen, Jari Kuopio, Teijo Aittomäki, Kristiina Mäkitie, Antti Pujol, Natalia Laisk, Triin Aalto-Setälä, Katriina Mäkelä, Johanna Hautalahti, Marco Smith, Sarah Southerington, Tom Kangasniemi, Eeva Palin, Henna Kähönen, Mika Siltanen, Sanna Laitinen, Tarja Vaura, Felix Suvisaari, Jaana Niiranen, Teemu Salomaa, Veikko Partanen, Jukka Arvas, Mikko Ritari, Jarmo Hyvärinen, Kati Choy, David Teng, Edmond Strauss, Erich Chen, Hao Chen, Hubert Schutzman, Jennifer Hunkapiller, Julie McCarthy, Mark Bowers, Natalie Pendergrass, Rion Lu, Tim Chu, Audrey Kulkarni, Diptee Xu, Fanli Betts, Joanna Eicher, John Gordillo, Jorge Esparza Addis, Laura McCarthy, Linda Mishra, Rajashree Kumar, Janet Ehm, Margaret G. Auro, Kirsi Pulford, David Pitkäranta, Anne Loukola, Anu Punkka, Eero Linna, Malla-Maria Carpén, Olli Raivio, Taneli Turunen, Joni A. Mäkelä, Tomi P. Salminen, Aino Aarnisalo, Antti Gordin, Daniel Rice, David Isometsä, Erkki Salminen, Eveliina Joensuu, Heikki Kalliala, Ilkka Mattson, Johanna Sinisalo, Juha Koskela, Jukka Eklund, Kari Hannula-Jouppi, Katariina Aaltonen, Lauri Taskinen, Marja-Riitta Färkkilä, Martti Raivio, Minna Heikinheimo, Oskari Kauppi, Paula Nieminen, Pekka Tienari, Pentti Pussinen, Pirkko Pikkarainen, Sampsa Ollila, Terhi Tuomi, Tiinamaija Hiltunen, Timo Meretoja, Tuomo Salo, Tuula Palotie, Ulla Palomäki, Antti Aittokallio, Jenni Rinne, Juha Metsärinne, Kaj Elenius, Klaus Pirilä, Laura Koulu, Leena Voutilainen, Markku Lahesmaa, Riitta Kallionpää, Roosa Peltonen, Sirkku Willberg, Tytti Gursoy, Ulvi Jokimaa, Varpu Palotie, Aarno Kytölä, Anastasia Ganna, Andrea Jalanko, Anu Liu, Aoxing Lehisto, Arto Ghazal, Awaisa Kilpeläinen, Elina Widen, Elisabeth Saarentaus, Elmo Pitkänen, Esa Ollila, Hanna Laivuori, Hannele Heyne, Henrike Shen, Huei-Yi Kaprio, Jaakko Rämö, Joel Karjalainen, Juha Mehtonen, Juha Pitkänen, Jyrki Pärn, Kalle Donner, Kati Kivinen, Katja Lahtela, L. Elisa Niemi, Mari E. Kaunisto, Mari Kals, Mart Reeve, Mary Pat Aavikko, Mervi Mars, Nina Dada, Oluwaseun Alexander Della Briotta Parolo, Pietro Palta, Priit Weldatsadik, Rigbe Kajanne, Risto Rodosthenous, Rodos Ripatti, Samuli Ruotsalainen, Sanni Strausz, Satu Hassan, Shabbeer Padmanabhuni, Shanmukha Sampath Luo, Shuang Lemmelä, Susanna Tukiainen, Taru Sipilä, Timo P. Kiiskinen, Tuomo Llorens, Vincent Daly, Mark Lee, Jiwoo Tsuo, Kristin Kurki, Mitja Elliott, Amanda Havulinna, Aki Partanen, Juulia Yang, Robert Reilly, Dermot Porello, Alessandro Hart, Amy Waterworth, Dawn Khramtsova, Ekaterina He, Karen Guan, Meijian Li, Qingqin S. Vuoti, Sauli Green, Eric Graham, Robert Mozaffari, Sahar Huertas-Vazquez, Adriana Loboda, Andrey Fox, Caroline Farias, Fabiana Sul, Jae-Hoon Miller, Jason Raghavan, Neha Longerich, Simonne Kettunen, Johannes Serpi, Raisa Hinttala, Reetta Mantere, Tuomo Remes, Anne Rahikkala, Elisa Huhtakangas, Johanna Tasanen, Kaisa Huilaja, Laura Morin-Papunen, Laure Niinimäki, Maarit Vääräsmäki, Marja Uimari, Outi Karihtala, Peeter Piltonen, Terhi Harju, Terttu Blomster, Timo Anttonen, Vuokko Soininen, Hilkka Kaarniranta, Kai Suominen, Liisa Pelkonen, Margit Siponen, Maria Kiviniemi, Mikko Kaipiainen-Seppänen, Oili Auvinen, Päivi Mäntylä, Päivi Kälviäinen, Reetta Julkunen, Valtteri O’Donnell, Chris Obeidat, Ma´en Renaud, Nicole Ngo, Debby Mouded, Majd Mendelson, Mike Mälarstig, Anders Lehtonen, Heli Parkkinen, Jaakko Kalpala, Kirsi Miller, Melissa Bing, Nan McDonough, Stefan Hu, Xinli Wu, Ying Jussila, Airi Auranen, Annika Bizaki-Vallaskangas, Argyro Uusitalo, Hannu Peltola, Jukka Hernesniemi, Jussi Kaukinen, Katri Kotaniemi-Talonen, Laura Isomäki, Pia Salmi, Teea Kurra, Venla Sipilä, Kirsi Toivola, Auli Järvensivu, Elina Kaiharju, Essi Mattsson, Hannele Kristiansson, Kati Männikkö, Lotta Laukkanen, Markku Perola, Markus Brunfeldt, Minna Laiho, Päivi Wong, Regis Koskelainen, Sami Lähteenmäki, Sini Soini, Sirpa Paajanen, Teemu Kilpi, Terhi Hiekkalinna, Tero Sistonen, Tuuli Chatelain, Clément Raipal, Deepak Klinger, Katherine Lessard, Samuel Åberg, Fredrik Hiltunen, Mikko Heikkinen, Sami Kankaanranta, Hannu Palotie, Tuula Hovatta, Iiris Palin, Kimmo Välimäki, Niko Toppila-Salmi, Sanna Laakkonen, Eija Sliz, Eeva Silven, Heidi Pylkäs, Katri Karjalainen, Minna Arffman, Riikka Savukoski, Susanna Tyrmi, Jaakko Rivas, Manuel Siirtola, Harri Vähätalo, Iida Garcia-Tabuenca, Javier Niemi, Marianna Helminen, Mika Luukkaala, Tiina Jennum, Poul Nevsimalova, Sona Kemlink, David Iranzo, Alex Overeem, Sebastiaan Wierzbicka, Aleksandra Geisler, Peter Sonka, Karel Honda, Makoto Högl, Birgit Stefani, Ambra Coelho, Fernando Morgadinho Mantovani, Vilma Feketeova, Eva Wadelius, Mia Eriksson, Niclas Smedje, Hans Hallberg, Pär Hesla, Per Egil Rye, David Pelin, Zerrin Ferini-Strambi, Luigi Bassetti, Claudio L. Mathis, Johannes Khatami, Ramin Aran, Adi Nampoothiri, Sheela Olsson, Tomas Kockum, Ingrid Partinen, Markku Perola, Markus Kornum, Birgitte R. Rueger, Sina Winkelmann, Juliane Miyagawa, Taku Toyoda, Hiromi Khor, Seik-Soon Shimada, Mihoko Tokunaga, Katsushi Rivas, Manuel Pritchard, Jonathan K. Risch, Neil Kutalik, Zoltan O’Hara, Ruth Hallmayer, Joachim Ye, Chun Jimmie Mignot, Emmanuel J. . Narcolepsy risk loci outline role of T cell autoimmunity and infectious triggers in narcolepsy. Nature Communications. 2023, 14(1)
dc.identifier.urihttp://hdl.handle.net/10852/108361
dc.description.abstractAbstract Narcolepsy type 1 (NT1) is caused by a loss of hypocretin/orexin transmission. Risk factors include pandemic 2009 H1N1 influenza A infection and immunization with Pandemrix®. Here, we dissect disease mechanisms and interactions with environmental triggers in a multi-ethnic sample of 6,073 cases and 84,856 controls. We fine-mapped GWAS signals within HLA (DQ0602, DQB1*03:01 and DPB1*04:02) and discovered seven novel associations (CD207, NAB1, IKZF4-ERBB3, CTSC, DENND1B, SIRPG, PRF1). Significant signals at TRA and DQB1*06:02 loci were found in 245 vaccination-related cases, who also shared polygenic risk. T cell receptor associations in NT1 modulated TRAJ*24, TRAJ*28 and TRBV*4-2 chain-usage. Partitioned heritability and immune cell enrichment analyses found genetic signals to be driven by dendritic and helper T cells. Lastly comorbidity analysis using data from FinnGen, suggests shared effects between NT1 and other autoimmune diseases. NT1 genetic variants shape autoimmunity and response to environmental triggers, including influenza A infection and immunization with Pandemrix®.
dc.languageEN
dc.rightsAttribution 4.0 International
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.titleNarcolepsy risk loci outline role of T cell autoimmunity and infectious triggers in narcolepsy
dc.title.alternativeENEngelskEnglishNarcolepsy risk loci outline role of T cell autoimmunity and infectious triggers in narcolepsy
dc.typeJournal article
dc.creator.authorOllila, Hanna M.
dc.creator.authorSharon, Eilon
dc.creator.authorLin, Ling
dc.creator.authorSinnott-Armstrong, Nasa
dc.creator.authorAmbati, Aditya
dc.creator.authorYogeshwar, Selina M.
dc.creator.authorHillary, Ryan P.
dc.creator.authorJolanki, Otto
dc.creator.authorFaraco, Juliette
dc.creator.authorEinen, Mali
dc.creator.authorLuo, Guo
dc.creator.authorZhang, Jing
dc.creator.authorHan, Fang
dc.creator.authorYan, Han
dc.creator.authorDong, Xiao Song
dc.creator.authorLi, Jing
dc.creator.authorZhang, Jun
dc.creator.authorHong, Seung-Chul
dc.creator.authorKim, Tae Won
dc.creator.authorDauvilliers, Yves
dc.creator.authorBarateau, Lucie
dc.creator.authorLammers, Gert Jan
dc.creator.authorFronczek, Rolf
dc.creator.authorMayer, Geert
dc.creator.authorSantamaria, Joan
dc.creator.authorArnulf, Isabelle
dc.creator.authorKnudsen, Stine
dc.creator.authorBredahl, May Kristin Lyamouri
dc.creator.authorThorsby, Per Medbøe
dc.creator.authorPlazzi, Giuseppe
dc.creator.authorPizza, Fabio
dc.creator.authorMoresco, Monica
dc.creator.authorCrowe, Catherine
dc.creator.authorVan den Eeden, Stephen K.
dc.creator.authorLecendreux, Michel
dc.creator.authorBourgin, Patrice
dc.creator.authorKanbayashi, Takashi
dc.creator.authorMartínez-Orozco, Francisco J.
dc.creator.authorPeraita-Adrados, Rosa
dc.creator.authorBenetó, Antonio
dc.creator.authorMontplaisir, Jacques
dc.creator.authorDesautels, Alex
dc.creator.authorHuang, Yu-Shu
dc.creator.authorAls, Thomas Damm
dc.creator.authorZiemann, Adam
dc.creator.authorAbbasi, Ali
dc.creator.authorLehtonen, Anne
dc.creator.authorLertratanakul, Apinya
dc.creator.authorRiley-Gillis, Bridget
dc.creator.authorRahimov, Fedik
dc.creator.authorJacob, Howard
dc.creator.authorWaring, Jeffrey
dc.creator.authorLiu, Mengzhen
dc.creator.authorSmaoui, Nizar
dc.creator.authorPopovic, Relja
dc.creator.authorPlatt, Adam
dc.creator.authorMatakidou, Athena
dc.creator.authorChallis, Benjamin
dc.creator.authorPaul, Dirk
dc.creator.authorLassi, Glenda
dc.creator.authorTachmazidou, Ioanna
dc.creator.authorHakanen, Antti
dc.creator.authorSchleutker, Johanna
dc.creator.authorPitkänen, Nina
dc.creator.authorTerho, Perttu
dc.creator.authorVirolainen, Petri
dc.creator.authorMannermaa, Arto
dc.creator.authorKosma, Veli-Matti
dc.creator.authorChen, Chia-Yen
dc.creator.authorRunz, Heiko
dc.creator.authorJohn, Sally
dc.creator.authorLahdenperä, Sanni
dc.creator.authorLoomis, Stephanie
dc.creator.authorEaton, Susan
dc.creator.authorOkafo, George
dc.creator.authorSalminen-Mankonen, Heli
dc.creator.authorJung, Marc
dc.creator.authorLawless, Nathan
dc.creator.authorDing, Zhihao
dc.creator.authorMaranville, Joseph
dc.creator.authorHochfeld, Marla
dc.creator.authorPlenge, Robert
dc.creator.authorBiswas, Shameek
dc.creator.authorKanai, Masahiro
dc.creator.authorMaasha, Mutaamba
dc.creator.authorZhou, Wei
dc.creator.authorTuovila, Outi
dc.creator.authorPakkanen, Raimo
dc.creator.authorLaukkanen, Jari
dc.creator.authorKuopio, Teijo
dc.creator.authorAittomäki, Kristiina
dc.creator.authorMäkitie, Antti
dc.creator.authorPujol, Natalia
dc.creator.authorLaisk, Triin
dc.creator.authorAalto-Setälä, Katriina
dc.creator.authorMäkelä, Johanna
dc.creator.authorHautalahti, Marco
dc.creator.authorSmith, Sarah
dc.creator.authorSoutherington, Tom
dc.creator.authorKangasniemi, Eeva
dc.creator.authorPalin, Henna
dc.creator.authorKähönen, Mika
dc.creator.authorSiltanen, Sanna
dc.creator.authorLaitinen, Tarja
dc.creator.authorVaura, Felix
dc.creator.authorSuvisaari, Jaana
dc.creator.authorNiiranen, Teemu
dc.creator.authorSalomaa, Veikko
dc.creator.authorPartanen, Jukka
dc.creator.authorArvas, Mikko
dc.creator.authorRitari, Jarmo
dc.creator.authorHyvärinen, Kati
dc.creator.authorChoy, David
dc.creator.authorTeng, Edmond
dc.creator.authorStrauss, Erich
dc.creator.authorChen, Hao
dc.creator.authorChen, Hubert
dc.creator.authorSchutzman, Jennifer
dc.creator.authorHunkapiller, Julie
dc.creator.authorMcCarthy, Mark
dc.creator.authorBowers, Natalie
dc.creator.authorPendergrass, Rion
dc.creator.authorLu, Tim
dc.creator.authorChu, Audrey
dc.creator.authorKulkarni, Diptee
dc.creator.authorXu, Fanli
dc.creator.authorBetts, Joanna
dc.creator.authorEicher, John
dc.creator.authorGordillo, Jorge Esparza
dc.creator.authorAddis, Laura
dc.creator.authorMcCarthy, Linda
dc.creator.authorMishra, Rajashree
dc.creator.authorKumar, Janet
dc.creator.authorEhm, Margaret G.
dc.creator.authorAuro, Kirsi
dc.creator.authorPulford, David
dc.creator.authorPitkäranta, Anne
dc.creator.authorLoukola, Anu
dc.creator.authorPunkka, Eero
dc.creator.authorLinna, Malla-Maria
dc.creator.authorCarpén, Olli
dc.creator.authorRaivio, Taneli
dc.creator.authorTurunen, Joni A.
dc.creator.authorMäkelä, Tomi P.
dc.creator.authorSalminen, Aino
dc.creator.authorAarnisalo, Antti
dc.creator.authorGordin, Daniel
dc.creator.authorRice, David
dc.creator.authorIsometsä, Erkki
dc.creator.authorSalminen, Eveliina
dc.creator.authorJoensuu, Heikki
dc.creator.authorKalliala, Ilkka
dc.creator.authorMattson, Johanna
dc.creator.authorSinisalo, Juha
dc.creator.authorKoskela, Jukka
dc.creator.authorEklund, Kari
dc.creator.authorHannula-Jouppi, Katariina
dc.creator.authorAaltonen, Lauri
dc.creator.authorTaskinen, Marja-Riitta
dc.creator.authorFärkkilä, Martti
dc.creator.authorRaivio, Minna
dc.creator.authorHeikinheimo, Oskari
dc.creator.authorKauppi, Paula
dc.creator.authorNieminen, Pekka
dc.creator.authorTienari, Pentti
dc.creator.authorPussinen, Pirkko
dc.creator.authorPikkarainen, Sampsa
dc.creator.authorOllila, Terhi
dc.creator.authorTuomi, Tiinamaija
dc.creator.authorHiltunen, Timo
dc.creator.authorMeretoja, Tuomo
dc.creator.authorSalo, Tuula
dc.creator.authorPalotie, Ulla
dc.creator.authorPalomäki, Antti
dc.creator.authorAittokallio, Jenni
dc.creator.authorRinne, Juha
dc.creator.authorMetsärinne, Kaj
dc.creator.authorElenius, Klaus
dc.creator.authorPirilä, Laura
dc.creator.authorKoulu, Leena
dc.creator.authorVoutilainen, Markku
dc.creator.authorLahesmaa, Riitta
dc.creator.authorKallionpää, Roosa
dc.creator.authorPeltonen, Sirkku
dc.creator.authorWillberg, Tytti
dc.creator.authorGursoy, Ulvi
dc.creator.authorJokimaa, Varpu
dc.creator.authorPalotie, Aarno
dc.creator.authorKytölä, Anastasia
dc.creator.authorGanna, Andrea
dc.creator.authorJalanko, Anu
dc.creator.authorLiu, Aoxing
dc.creator.authorLehisto, Arto
dc.creator.authorGhazal, Awaisa
dc.creator.authorKilpeläinen, Elina
dc.creator.authorWiden, Elisabeth
dc.creator.authorSaarentaus, Elmo
dc.creator.authorPitkänen, Esa
dc.creator.authorOllila, Hanna
dc.creator.authorLaivuori, Hannele
dc.creator.authorHeyne, Henrike
dc.creator.authorShen, Huei-Yi
dc.creator.authorKaprio, Jaakko
dc.creator.authorRämö, Joel
dc.creator.authorKarjalainen, Juha
dc.creator.authorMehtonen, Juha
dc.creator.authorPitkänen, Jyrki
dc.creator.authorPärn, Kalle
dc.creator.authorDonner, Kati
dc.creator.authorKivinen, Katja
dc.creator.authorLahtela, L. Elisa
dc.creator.authorNiemi, Mari E.
dc.creator.authorKaunisto, Mari
dc.creator.authorKals, Mart
dc.creator.authorReeve, Mary Pat
dc.creator.authorAavikko, Mervi
dc.creator.authorMars, Nina
dc.creator.authorDada, Oluwaseun Alexander
dc.creator.authorDella Briotta Parolo, Pietro
dc.creator.authorPalta, Priit
dc.creator.authorWeldatsadik, Rigbe
dc.creator.authorKajanne, Risto
dc.creator.authorRodosthenous, Rodos
dc.creator.authorRipatti, Samuli
dc.creator.authorRuotsalainen, Sanni
dc.creator.authorStrausz, Satu
dc.creator.authorHassan, Shabbeer
dc.creator.authorPadmanabhuni, Shanmukha Sampath
dc.creator.authorLuo, Shuang
dc.creator.authorLemmelä, Susanna
dc.creator.authorTukiainen, Taru
dc.creator.authorSipilä, Timo P.
dc.creator.authorKiiskinen, Tuomo
dc.creator.authorLlorens, Vincent
dc.creator.authorDaly, Mark
dc.creator.authorLee, Jiwoo
dc.creator.authorTsuo, Kristin
dc.creator.authorKurki, Mitja
dc.creator.authorElliott, Amanda
dc.creator.authorHavulinna, Aki
dc.creator.authorPartanen, Juulia
dc.creator.authorYang, Robert
dc.creator.authorReilly, Dermot
dc.creator.authorPorello, Alessandro
dc.creator.authorHart, Amy
dc.creator.authorWaterworth, Dawn
dc.creator.authorKhramtsova, Ekaterina
dc.creator.authorHe, Karen
dc.creator.authorGuan, Meijian
dc.creator.authorLi, Qingqin S.
dc.creator.authorVuoti, Sauli
dc.creator.authorGreen, Eric
dc.creator.authorGraham, Robert
dc.creator.authorMozaffari, Sahar
dc.creator.authorHuertas-Vazquez, Adriana
dc.creator.authorLoboda, Andrey
dc.creator.authorFox, Caroline
dc.creator.authorFarias, Fabiana
dc.creator.authorSul, Jae-Hoon
dc.creator.authorMiller, Jason
dc.creator.authorRaghavan, Neha
dc.creator.authorLongerich, Simonne
dc.creator.authorKettunen, Johannes
dc.creator.authorSerpi, Raisa
dc.creator.authorHinttala, Reetta
dc.creator.authorMantere, Tuomo
dc.creator.authorRemes, Anne
dc.creator.authorRahikkala, Elisa
dc.creator.authorHuhtakangas, Johanna
dc.creator.authorTasanen, Kaisa
dc.creator.authorHuilaja, Laura
dc.creator.authorMorin-Papunen, Laure
dc.creator.authorNiinimäki, Maarit
dc.creator.authorVääräsmäki, Marja
dc.creator.authorUimari, Outi
dc.creator.authorKarihtala, Peeter
dc.creator.authorPiltonen, Terhi
dc.creator.authorHarju, Terttu
dc.creator.authorBlomster, Timo
dc.creator.authorAnttonen, Vuokko
dc.creator.authorSoininen, Hilkka
dc.creator.authorKaarniranta, Kai
dc.creator.authorSuominen, Liisa
dc.creator.authorPelkonen, Margit
dc.creator.authorSiponen, Maria
dc.creator.authorKiviniemi, Mikko
dc.creator.authorKaipiainen-Seppänen, Oili
dc.creator.authorAuvinen, Päivi
dc.creator.authorMäntylä, Päivi
dc.creator.authorKälviäinen, Reetta
dc.creator.authorJulkunen, Valtteri
dc.creator.authorO’Donnell, Chris
dc.creator.authorObeidat, Ma´en
dc.creator.authorRenaud, Nicole
dc.creator.authorNgo, Debby
dc.creator.authorMouded, Majd
dc.creator.authorMendelson, Mike
dc.creator.authorMälarstig, Anders
dc.creator.authorLehtonen, Heli
dc.creator.authorParkkinen, Jaakko
dc.creator.authorKalpala, Kirsi
dc.creator.authorMiller, Melissa
dc.creator.authorBing, Nan
dc.creator.authorMcDonough, Stefan
dc.creator.authorHu, Xinli
dc.creator.authorWu, Ying
dc.creator.authorJussila, Airi
dc.creator.authorAuranen, Annika
dc.creator.authorBizaki-Vallaskangas, Argyro
dc.creator.authorUusitalo, Hannu
dc.creator.authorPeltola, Jukka
dc.creator.authorHernesniemi, Jussi
dc.creator.authorKaukinen, Katri
dc.creator.authorKotaniemi-Talonen, Laura
dc.creator.authorIsomäki, Pia
dc.creator.authorSalmi, Teea
dc.creator.authorKurra, Venla
dc.creator.authorSipilä, Kirsi
dc.creator.authorToivola, Auli
dc.creator.authorJärvensivu, Elina
dc.creator.authorKaiharju, Essi
dc.creator.authorMattsson, Hannele
dc.creator.authorKristiansson, Kati
dc.creator.authorMännikkö, Lotta
dc.creator.authorLaukkanen, Markku
dc.creator.authorPerola, Markus
dc.creator.authorBrunfeldt, Minna
dc.creator.authorLaiho, Päivi
dc.creator.authorWong, Regis
dc.creator.authorKoskelainen, Sami
dc.creator.authorLähteenmäki, Sini
dc.creator.authorSoini, Sirpa
dc.creator.authorPaajanen, Teemu
dc.creator.authorKilpi, Terhi
dc.creator.authorHiekkalinna, Tero
dc.creator.authorSistonen, Tuuli
dc.creator.authorChatelain, Clément
dc.creator.authorRaipal, Deepak
dc.creator.authorKlinger, Katherine
dc.creator.authorLessard, Samuel
dc.creator.authorÅberg, Fredrik
dc.creator.authorHiltunen, Mikko
dc.creator.authorHeikkinen, Sami
dc.creator.authorKankaanranta, Hannu
dc.creator.authorPalotie, Tuula
dc.creator.authorHovatta, Iiris
dc.creator.authorPalin, Kimmo
dc.creator.authorVälimäki, Niko
dc.creator.authorToppila-Salmi, Sanna
dc.creator.authorLaakkonen, Eija
dc.creator.authorSliz, Eeva
dc.creator.authorSilven, Heidi
dc.creator.authorPylkäs, Katri
dc.creator.authorKarjalainen, Minna
dc.creator.authorArffman, Riikka
dc.creator.authorSavukoski, Susanna
dc.creator.authorTyrmi, Jaakko
dc.creator.authorRivas, Manuel
dc.creator.authorSiirtola, Harri
dc.creator.authorVähätalo, Iida
dc.creator.authorGarcia-Tabuenca, Javier
dc.creator.authorNiemi, Marianna
dc.creator.authorHelminen, Mika
dc.creator.authorLuukkaala, Tiina
dc.creator.authorJennum, Poul
dc.creator.authorNevsimalova, Sona
dc.creator.authorKemlink, David
dc.creator.authorIranzo, Alex
dc.creator.authorOvereem, Sebastiaan
dc.creator.authorWierzbicka, Aleksandra
dc.creator.authorGeisler, Peter
dc.creator.authorSonka, Karel
dc.creator.authorHonda, Makoto
dc.creator.authorHögl, Birgit
dc.creator.authorStefani, Ambra
dc.creator.authorCoelho, Fernando Morgadinho
dc.creator.authorMantovani, Vilma
dc.creator.authorFeketeova, Eva
dc.creator.authorWadelius, Mia
dc.creator.authorEriksson, Niclas
dc.creator.authorSmedje, Hans
dc.creator.authorHallberg, Pär
dc.creator.authorHesla, Per Egil
dc.creator.authorRye, David
dc.creator.authorPelin, Zerrin
dc.creator.authorFerini-Strambi, Luigi
dc.creator.authorBassetti, Claudio L.
dc.creator.authorMathis, Johannes
dc.creator.authorKhatami, Ramin
dc.creator.authorAran, Adi
dc.creator.authorNampoothiri, Sheela
dc.creator.authorOlsson, Tomas
dc.creator.authorKockum, Ingrid
dc.creator.authorPartinen, Markku
dc.creator.authorPerola, Markus
dc.creator.authorKornum, Birgitte R.
dc.creator.authorRueger, Sina
dc.creator.authorWinkelmann, Juliane
dc.creator.authorMiyagawa, Taku
dc.creator.authorToyoda, Hiromi
dc.creator.authorKhor, Seik-Soon
dc.creator.authorShimada, Mihoko
dc.creator.authorTokunaga, Katsushi
dc.creator.authorRivas, Manuel
dc.creator.authorPritchard, Jonathan K.
dc.creator.authorRisch, Neil
dc.creator.authorKutalik, Zoltan
dc.creator.authorO’Hara, Ruth
dc.creator.authorHallmayer, Joachim
dc.creator.authorYe, Chun Jimmie
dc.creator.authorMignot, Emmanuel J.
cristin.unitcode185,53,46,10
cristin.unitnamePediatri
cristin.ispublishedtrue
cristin.fulltextoriginal
cristin.qualitycode2
dc.identifier.cristin2166996
dc.identifier.bibliographiccitationinfo:ofi/fmt:kev:mtx:ctx&ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Nature Communications&rft.volume=14&rft.spage=&rft.date=2023
dc.identifier.jtitleNature Communications
dc.identifier.volume14
dc.identifier.issue1
dc.identifier.pagecount0
dc.identifier.doihttps://doi.org/10.1038/s41467-023-36120-z
dc.type.documentTidsskriftartikkel
dc.type.peerreviewedPeer reviewed
dc.source.issn2041-1723
dc.type.versionPublishedVersion
cristin.articleid2709


Files in this item

Name:
Ollila_et_al_2023.pdf
Size:
4.288Mb
Format:
application/
View/Open

Appears in the following Collection

Hide metadata

Attribution 4.0 International
This item's license is: Attribution 4.0 International