dc.date.accessioned | 2024-02-01T09:34:20Z | |
dc.date.available | 2024-02-01T09:34:20Z | |
dc.date.created | 2023-11-27T17:07:28Z | |
dc.date.issued | 2023 | |
dc.identifier.citation | Bråthen, Camilla Christin Jørgenrud, Benedicte Marie Bogstrand, Stig Tore Gjerde, Hallvard Rosseland, Leiv Arne Kristiansen, Thomas . Prevalence of use and impairment from drugs and alcohol among trauma patients: A national prospective observational study. Injury. 2023, 54(12) | |
dc.identifier.uri | http://hdl.handle.net/10852/107344 | |
dc.description.abstract | Background: Being under the influence of psychoactive substances increases the risk of involvement in and dying from a traumatic event. The study is a prospective population-based observational study that aims to determine the prevalence of use and likely impairment from psychoactive substances among patients with suspected severe traumatic injury. Method: This study was conducted at 35 of 38 Norwegian trauma hospitals from 1 March 2019 to 29 February 2020. All trauma admissions for patients aged ≥ 16 years admitted via trauma team activation during the study period were eligible for inclusion. Blood samples collected on admission were analysed for alcohol, benzodiazepines, benzodiazepine-like hypnotics (Z-drugs), opioids, stimulants, and cannabis (tetrahydrocannabinol). Results: Of the 4878 trauma admissions included, psychoactive substances were detected in 1714 (35 %) and in 771 (45 %) of these, a combination of two or more psychoactive substances was detected. Regarding the level of impairment, 1373 (28 %) admissions revealed a concentration of one or more psychoactive substances indicating likely impairment, and 1052 (22 %) highly impairment. Alcohol was found in 1009 (21 %) admissions, benzodiazepines and Z-drugs in 613 (13 %), opioids in 467 (10 %), cannabis in 352 (7 %), and stimulants in 371 (8 %). Men aged 27-43 years and patients with violence-related trauma had the highest prevalence of psychoactive substance use with respectively 424 (50 %) and 275 (80 %) testing positive for one or more compounds. Conclusion: The results revealed psychoactive substances in 35 % of trauma admissions, 80 % of which were likely impaired at the time of traumatic injury. A combination of several psychoactive substances was common, and younger males and patients with violence-related injuries were most often impaired. Injury prevention strategies should focus on high-risk groups and involve the prescription of controlled substances. We should consider toxicological screening in trauma admissions and incorporation of toxicological data into trauma registries. | |
dc.language | EN | |
dc.rights | Attribution-NonCommercial 4.0 International | |
dc.rights.uri | https://creativecommons.org/licenses/by-nc/4.0/ | |
dc.title | Prevalence of use and impairment from drugs and alcohol among trauma patients: A national prospective observational study | |
dc.title.alternative | ENEngelskEnglishPrevalence of use and impairment from drugs and alcohol among trauma patients: A national prospective observational study | |
dc.type | Journal article | |
dc.creator.author | Bråthen, Camilla Christin | |
dc.creator.author | Jørgenrud, Benedicte Marie | |
dc.creator.author | Bogstrand, Stig Tore | |
dc.creator.author | Gjerde, Hallvard | |
dc.creator.author | Rosseland, Leiv Arne | |
dc.creator.author | Kristiansen, Thomas | |
cristin.unitcode | 185,90,0,0 | |
cristin.unitname | Universitetet i Oslo | |
cristin.ispublished | true | |
cristin.fulltext | original | |
cristin.qualitycode | 1 | |
dc.identifier.cristin | 2203272 | |
dc.identifier.bibliographiccitation | info:ofi/fmt:kev:mtx:ctx&ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Injury&rft.volume=54&rft.spage=&rft.date=2023 | |
dc.identifier.jtitle | Injury | |
dc.identifier.volume | 54 | |
dc.identifier.issue | 12 | |
dc.identifier.pagecount | 9 | |
dc.identifier.doi | https://doi.org/10.1016/j.injury.2023.111160 | |
dc.type.document | Tidsskriftartikkel | |
dc.type.peerreviewed | Peer reviewed | |
dc.source.issn | 0020-1383 | |
dc.type.version | PublishedVersion | |
cristin.articleid | 111160 | |