dc.date.accessioned | 2024-01-31T17:22:26Z | |
dc.date.available | 2024-01-31T17:22:26Z | |
dc.date.created | 2024-01-04T13:32:19Z | |
dc.date.issued | 2023 | |
dc.identifier.citation | Bhatnagar, Rahul Berge, Kristian Røysland, Ragnhild Høiseth, Arne Didrik Brynildsen, Jon Christensen, Geir Omland, Torbjørn Røsjø, Helge Rørvik Lyngbakken, Magnus Nakrem . Cardiac Troponin T and NT-proBNP for Prediction of 30-Day Readmission or Death in Patients with Acute Dyspnea: Data from the Akershus Cardiac Examination 2 Study. Cardiology. 2023, 148(6), 506-516 | |
dc.identifier.uri | http://hdl.handle.net/10852/107301 | |
dc.description.abstract | Introduction: N-terminal pro-B-type natriuretic peptide (NT-proBNP) and cardiac troponin T (cTnT) measurements are recommended in patients with acute dyspnea. We aimed to assess the prognostic merit of cTnT compared to NT-proBNP for 30-day readmission or death in patients hospitalized with acute dyspnea. Methods: We measured cTnT and NT-proBNP within 24 h in 314 patients hospitalized with acute dyspnea and adjudicated the cause of the index admission. Time to first event of readmission or death ≤30 days after hospital discharge was recorded, and cTnT and NT-proBNP measurements were compared head-to-head. Results: Patients who died (12/314) or were readmitted (71/314) within 30 days had higher cTnT concentrations (median: 32.6, Q1–Q3: 18.4–74.2 ng/L vs. median: 19.4, Q1–Q3: 8.4–36.1 ng/L; p for comparison <0.001) and NT-proBNP concentrations (median: 1,753.6, Q1–Q3: 464.2–6,862.0 ng/L vs. median 984, Q1–Q3 201–3,600 ng/L; for comparison p = 0.027) compared to patients who survived and were not readmitted. cTnT concentrations were associated with readmission or death within 30 days after discharge both in the total cohort (adjusted hazard ratio [aHR]: 1.64, 95% confidence interval [CI]: 1.30–2.05) and in patients with heart failure (HF) (aHR: 1.58, 95% CI: 1.14–2.18). In contrast, NT-proBNP concentrations were not associated with short-term events, neither in the total cohort (aHR: 1.10, 95% CI: 0.94–1.30) nor in patients with adjudicated HF (aHR: 1.06, 95% CI: 0.80–1.40). Conclusion: cTnT concentrations are associated with 30-day readmission or death in patients hospitalized with acute dyspnea, as well as in patients adjudicated HF. | |
dc.language | EN | |
dc.rights | Attribution 4.0 International | |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | |
dc.title | Cardiac Troponin T and NT-proBNP for Prediction of 30-Day Readmission or Death in Patients with Acute Dyspnea: Data from the Akershus Cardiac Examination 2 Study | |
dc.title.alternative | ENEngelskEnglishCardiac Troponin T and NT-proBNP for Prediction of 30-Day Readmission or Death in Patients with Acute Dyspnea: Data from the Akershus Cardiac Examination 2 Study | |
dc.type | Journal article | |
dc.creator.author | Bhatnagar, Rahul | |
dc.creator.author | Berge, Kristian | |
dc.creator.author | Røysland, Ragnhild | |
dc.creator.author | Høiseth, Arne Didrik | |
dc.creator.author | Brynildsen, Jon | |
dc.creator.author | Christensen, Geir | |
dc.creator.author | Omland, Torbjørn | |
dc.creator.author | Røsjø, Helge Rørvik | |
dc.creator.author | Lyngbakken, Magnus Nakrem | |
cristin.unitcode | 185,53,82,0 | |
cristin.unitname | Klinikk for indremedisin og lab fag | |
cristin.ispublished | true | |
cristin.fulltext | original | |
cristin.qualitycode | 1 | |
dc.identifier.cristin | 2220634 | |
dc.identifier.bibliographiccitation | info:ofi/fmt:kev:mtx:ctx&ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Cardiology&rft.volume=148&rft.spage=506&rft.date=2023 | |
dc.identifier.jtitle | Cardiology | |
dc.identifier.volume | 148 | |
dc.identifier.issue | 6 | |
dc.identifier.startpage | 506 | |
dc.identifier.endpage | 516 | |
dc.identifier.doi | https://doi.org/10.1159/000533266 | |
dc.type.document | Tidsskriftartikkel | |
dc.type.peerreviewed | Peer reviewed | |
dc.source.issn | 0008-6312 | |
dc.type.version | PublishedVersion | |