The relationship between genetic liability, childhood maltreatment, and IQ: findings from the EU-GEI multicentric case–control study
dc.date.accessioned | 2024-01-15T18:35:14Z | |
dc.date.available | 2024-01-15T18:35:14Z | |
dc.date.created | 2023-08-16T11:01:36Z | |
dc.date.issued | 2023 | |
dc.identifier.citation | Sideli, Lucia Aas, Monica Quattrone, Diego La Barbera, Daniele La Cascia, Caterina Ferraro, Laura Alameda, Luis Velthorst, Eva Trotta, Giulia Tripoli, Giada Schimmenti, Adriano Fontana, Andrea Gayer-Anderson, Charlotte Stilo, Simona Seminerio, Fabio Sartorio, Crocettarachele Marrazzo, Giovanna Lasalvia, Antonio Tosato, Sarah Tarricone, Ilaria Berardi, Domenico D’Andrea, Giuseppe Arango, Celso Arrojo, Manuel Bernardo, Miguel Bobes, Julio Sanjuán, Julio Santos, Jose Luis Menezes, Paulo Rossi Del-Ben, Cristina Marta Jongsma, Hannah E. Jones, Peter B Kirkbride, James B. Llorca, Pierre-Michel Tortelli, Andrea Pignon, Baptiste De Haan, Lieuwe Selten, Jean-Paul Van Os, Jim Rutten, Bart P Bentall, Richard Di Forti, Marta Murray, Robin M. Morgan, Craig Fisher, Helen L. . The relationship between genetic liability, childhood maltreatment, and IQ: findings from the EU-GEI multicentric case–control study. Social Psychiatry and Psychiatric Epidemiology. 2023, 58, 1573-1580 | |
dc.identifier.uri | http://hdl.handle.net/10852/106861 | |
dc.description.abstract | Abstract This study investigated if the association between childhood maltreatment and cognition among psychosis patients and community controls was partially accounted for by genetic liability for psychosis. Patients with first-episode psychosis ( N = 755) and unaffected controls ( N = 1219) from the EU-GEI study were assessed for childhood maltreatment, intelligence quotient (IQ), family history of psychosis (FH), and polygenic risk score for schizophrenia (SZ-PRS). Controlling for FH and SZ-PRS did not attenuate the association between childhood maltreatment and IQ in cases or controls. Findings suggest that these expressions of genetic liability cannot account for the lower levels of cognition found among adults maltreated in childhood. | |
dc.language | EN | |
dc.rights | Attribution 4.0 International | |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | |
dc.title | The relationship between genetic liability, childhood maltreatment, and IQ: findings from the EU-GEI multicentric case–control study | |
dc.title.alternative | ENEngelskEnglishThe relationship between genetic liability, childhood maltreatment, and IQ: findings from the EU-GEI multicentric case–control study | |
dc.type | Journal article | |
dc.creator.author | Sideli, Lucia | |
dc.creator.author | Aas, Monica | |
dc.creator.author | Quattrone, Diego | |
dc.creator.author | La Barbera, Daniele | |
dc.creator.author | La Cascia, Caterina | |
dc.creator.author | Ferraro, Laura | |
dc.creator.author | Alameda, Luis | |
dc.creator.author | Velthorst, Eva | |
dc.creator.author | Trotta, Giulia | |
dc.creator.author | Tripoli, Giada | |
dc.creator.author | Schimmenti, Adriano | |
dc.creator.author | Fontana, Andrea | |
dc.creator.author | Gayer-Anderson, Charlotte | |
dc.creator.author | Stilo, Simona | |
dc.creator.author | Seminerio, Fabio | |
dc.creator.author | Sartorio, Crocettarachele | |
dc.creator.author | Marrazzo, Giovanna | |
dc.creator.author | Lasalvia, Antonio | |
dc.creator.author | Tosato, Sarah | |
dc.creator.author | Tarricone, Ilaria | |
dc.creator.author | Berardi, Domenico | |
dc.creator.author | D’Andrea, Giuseppe | |
dc.creator.author | Arango, Celso | |
dc.creator.author | Arrojo, Manuel | |
dc.creator.author | Bernardo, Miguel | |
dc.creator.author | Bobes, Julio | |
dc.creator.author | Sanjuán, Julio | |
dc.creator.author | Santos, Jose Luis | |
dc.creator.author | Menezes, Paulo Rossi | |
dc.creator.author | Del-Ben, Cristina Marta | |
dc.creator.author | Jongsma, Hannah E. | |
dc.creator.author | Jones, Peter B | |
dc.creator.author | Kirkbride, James B. | |
dc.creator.author | Llorca, Pierre-Michel | |
dc.creator.author | Tortelli, Andrea | |
dc.creator.author | Pignon, Baptiste | |
dc.creator.author | De Haan, Lieuwe | |
dc.creator.author | Selten, Jean-Paul | |
dc.creator.author | Van Os, Jim | |
dc.creator.author | Rutten, Bart P | |
dc.creator.author | Bentall, Richard | |
dc.creator.author | Di Forti, Marta | |
dc.creator.author | Murray, Robin M. | |
dc.creator.author | Morgan, Craig | |
dc.creator.author | Fisher, Helen L. | |
cristin.unitcode | 185,53,10,70 | |
cristin.unitname | Senter for presisjonspsykiatri | |
cristin.ispublished | true | |
cristin.fulltext | original | |
cristin.qualitycode | 2 | |
dc.identifier.cristin | 2167293 | |
dc.identifier.bibliographiccitation | info:ofi/fmt:kev:mtx:ctx&ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Social Psychiatry and Psychiatric Epidemiology&rft.volume=58&rft.spage=1573&rft.date=2023 | |
dc.identifier.jtitle | Social Psychiatry and Psychiatric Epidemiology | |
dc.identifier.volume | 58 | |
dc.identifier.issue | 10 | |
dc.identifier.startpage | 1573 | |
dc.identifier.endpage | 1580 | |
dc.identifier.doi | https://doi.org/10.1007/s00127-023-02513-0 | |
dc.type.document | Tidsskriftartikkel | |
dc.type.peerreviewed | Peer reviewed | |
dc.source.issn | 0933-7954 | |
dc.type.version | PublishedVersion |
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