dc.date.accessioned | 2023-03-12T17:21:27Z | |
dc.date.available | 2023-03-12T17:21:27Z | |
dc.date.created | 2023-01-02T17:11:21Z | |
dc.date.issued | 2022 | |
dc.identifier.citation | Rød, Emma Solberg, Vilde Stenersen, Eydis Oddsdottir Garberg, Håvard Tetlie Mjelle, Anders Batman Tølløfsrud, Per Arne Rønnestad, Arild Erland Solevåg, Anne Lee . Biochemical surveillance versus clinical observation of term infants born after prolonged rupture of membranes – A quality assurance initiative. Acta Paediatrica. 2022, 112(3), 391-397 | |
dc.identifier.uri | http://hdl.handle.net/10852/101323 | |
dc.description.abstract | Aim To examine whether biochemical surveillance vs clinical observation of term infants with prolonged rupture of membranes as a risk factor for early-onset sepsis is associated with differences in patient trajectories in maternity and neonatal intensive care units. Methods A retrospective study of live-born infants with gestational age ≥ 37 + 0 weeks born after prolonged rupture of membranes (≥24 h) in four Norwegian hospitals 2017–2019. Two hospitals used biochemical surveillance, and two used predominantly clinical observation to identify early-onset sepsis cases. Results The biochemical surveillance hospitals had more C-reactive protein measurements (p < 0.001), neonatal intensive care unit admissions (p < 0.001) and antibiotic treatment (p < 0.001). Hospitals using predominantly clinical observation initiated antibiotic treatment earlier in infants with suspected early-onset sepsis (p = 0.04) but not in infants fulfilling early-onset sepsis diagnostic criteria (p = 0.09). There was no difference in antibiotic treatment duration (p = 0.59), fraction of infants fulfilling early-onset sepsis diagnostic criteria (p = 0.49) or length of hospitalisation (p = 0.30), and no early-onset sepsis-related adverse outcomes. Conclusion The biochemical surveillance hospitals had more C-reactive protein measurements, but there was no difference in antibiotic treatment duration, early-onset sepsis cases, length of hospitalisation or adverse outcomes. Personnel resources needed for clinical surveillance should be weighed against the limitation of potentially painful procedures. | |
dc.language | EN | |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 International | |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/4.0/ | |
dc.title | Biochemical surveillance versus clinical observation of term infants born after prolonged rupture of membranes – A quality assurance initiative | |
dc.title.alternative | ENEngelskEnglishBiochemical surveillance versus clinical observation of term infants born after prolonged rupture of membranes – A quality assurance initiative | |
dc.type | Journal article | |
dc.creator.author | Rød, Emma | |
dc.creator.author | Solberg, Vilde | |
dc.creator.author | Stenersen, Eydis Oddsdottir | |
dc.creator.author | Garberg, Håvard Tetlie | |
dc.creator.author | Mjelle, Anders Batman | |
dc.creator.author | Tølløfsrud, Per Arne | |
dc.creator.author | Rønnestad, Arild Erland | |
dc.creator.author | Solevåg, Anne Lee | |
cristin.unitcode | 185,53,46,10 | |
cristin.unitname | Pediatri | |
cristin.ispublished | true | |
cristin.fulltext | original | |
cristin.qualitycode | 1 | |
dc.identifier.cristin | 2099117 | |
dc.identifier.bibliographiccitation | info:ofi/fmt:kev:mtx:ctx&ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Acta Paediatrica&rft.volume=112&rft.spage=391&rft.date=2022 | |
dc.identifier.jtitle | Acta Paediatrica | |
dc.identifier.volume | 112 | |
dc.identifier.issue | 3 | |
dc.identifier.startpage | 391 | |
dc.identifier.endpage | 397 | |
dc.identifier.doi | https://doi.org/10.1111/apa.16617 | |
dc.type.document | Tidsskriftartikkel | |
dc.type.peerreviewed | Peer reviewed | |
dc.source.issn | 0803-5253 | |
dc.type.version | PublishedVersion | |