Browsing by Title
Now showing items 59294-59313 of 97529
-
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)Background The conversions of the n-3 and n-6 fatty acid of plant origin to the C20 and C22 very long chain fatty acids (LCPUFAs) is regulated by several cellular enzymes such as elongases and desaturases. ...
-
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)Today, the majority of patients with pediatric B cell precursor acute lymphoblastic leukemia (BCP-ALL, hereafter ALL) survive their disease, but many of the survivors suffer from life-limiting late effects of the treatment. ...
-
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)N-acetyl-aspartyl-glutamate (NAAG) is the most abundant dipeptide in the brain, where it acts as a neuromodulator of glutamatergic synapses by activating presynaptic metabotropic glutamate receptor 3 (mGluR3). Recent data ...
-
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)In our recent studies, we identified compound N-benzyl-2-(2,5-dioxopyrrolidin-1-yl)propanamide (AS-1) as a broad-spectrum hybrid anticonvulsant which showed potent protection across the most important animal acute seizure ...
-
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2011)We introduce the N-body simulation technique to follow structure formation in linear and nonlinear regimes for the extended quintessence models (scalar-tensor theories in which the scalar field has a self-interaction ...
-
(Master thesis / Masteroppgave, 2014)Neutrinos are very weakly interacting particles with a low mass. In fact, the mass of the neutrinos has not yet been determined by experiments or observations. Still, neutrinos are a good candidate for some of the dark ...
-
(Master thesis / Masteroppgave, 2015)Legumain er en asparaginyl endopeptidase som generelt er uttrykt i de fleste normale humane vev. Studier har imidlertid vist at proteinuttrykket av legumain er oppregulert i flere faste svulster. Høyt uttrykk av legumain ...
-
(Master thesis / Masteroppgave, 2014)LC-MS-teknologien har enda ikke utviklet seg nok til å kunne detektere intakte proteiner og deres postranslationelle modifikasjoner (PTM), fra biologiske matrikser uten prøveopparbeidelse. Derfor benyttes fortsatt ...
-
(Doctoral thesis / Doktoravhandling, 2014)Gangliosides are sialic acid-containing glycosphingolipids expressed on all vertebrate cells. They are primarily positioned in the plasma membrane, with the ceramide part anchored in the membrane and the glycan part exposed ...
-
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)We report a mild superbase-catalyzed and nitrogen-selective carboxylation of N-heteroaryls, with subsequent alkylation enabling the synthesis of drug-like O-alkyl carbamates in good yields (av. 86%). Our findings suggest ...
-
(Master thesis / Masteroppgave, 2014)Metastasis (spread of cancer cells) is the major cause of cancer related deaths. The reason why cancer cells spreads is largely unknown, but proteinases have been suggested to take part in this process. The proteinases ...
-
N-Linked Glycosylation Supports Cross-Talk between Receptor Tyrosine Kinases and Androgen Receptor (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)Prostate cancer is the second most common cause of cancer-associated deaths in men and signalling via a transcription factor called androgen receptor (AR) is an important driver of the disease. Androgen treatment is known ...
-
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)The sodium dependent bicarbonate transporter NCBE/NBCn2 is predominantly expressed in the central nervous system (CNS). The highest protein concentrations are found in the choroid plexus. The primary function of this ...
-
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)Background Early risk stratification applying cardiac biomarkers may prove useful in sudden cardiac arrest patients. We investigated the prognostic utility of early-on levels of high sensitivity cardiac troponin-T (hs-cTnT), ...
-
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)Abstract Background Elevated N‐terminal pro‐B‐type natriuretic peptide (NT‐proBNP) concentrations predict heart failure (HF) and mortality, but whether NT‐proBNP predicts ventricular arrhythmias (VA) is not clear. ...
-
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)N6-methyladenosine (m 6 A) deposition on messenger RNA (mRNA) controls embryonic stem cell (ESC) fate by regulating the mRNA stabilities of pluripotency and lineage transcription factors (TFs) [P. J. Batista et al., Cell ...
-
N6-methyladenosine (m6A) regulates signaling pathways during early embryo developmentRestricted Access (Doctoral thesis / Doktoravhandling, 2022)N6-methyladenosine (m6A) is the most abundant internal modification in eukaryotic mRNA. In recent years, a slew of interesting studies had confirmed its essential role as a post-transcriptional regulator of gene expression ...
-
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)Background More than 170 post-transcriptional RNA modifications regulate the localization, processing and function of cellular RNAs, and aberrant RNA modifications have been linked to a range of human diseases. The RNA ...
-
(Doctoral thesis / Doktoravhandling, 2016)
-
Naboeffekt i verdens elbilhovedstad Har sosial påvirkning bidratt til spredningen av elbiler i Oslo? (Master thesis / Group thesis / Hovedoppgave / Gruppeoppgave, 2018)Bakgrunn og mål. Verden står overfor store klimautfordringer. For å redusere klimagassutslipp kan implementering av grønn teknologi spille en avgjørende rolle. I Norge er overgangen til nullutslippskjøretøy en politisk ...